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Magnetic resonance imaging (MRI) is a cornerstone of clinical neuroimaging, yet conventional MRIs provide qualitative information heavily dependent on scanner hardware and acquisition settings. While quantitative MRI (qMRI) offers intrinsic…
The performance and diagnostic utility of magnetic resonance imaging (MRI) in pregnancy is fundamentally constrained by fetal motion. Motion of the fetus, which is unpredictable and rapid on the scale of conventional imaging times, limits…
Accurate tissue segmentation of thick-slice fetal brain magnetic resonance (MR) scans is crucial for both reconstruction of isotropic brain MR volumes and the quantification of fetal brain development. However, this task is challenging due…
Head motion is an omnipresent confounder of magnetic resonance image (MRI) analyses as it systematically affects morphometric measurements, even when visual quality control is performed. In order to estimate subtle head motion, that remains…
Brain segmentation is a fundamental first step in neuroimage analysis. In the case of fetal MRI, it is particularly challenging and important due to the arbitrary orientation of the fetus, organs that surround the fetal head, and…
We present a microstructure imaging technique for estimating compartment-specific T2 and T2* simultaneously in the human brain. Microstructure imaging with diffusion MRI (dMRI) has enabled the modelling of intra-neurite and extra-neurite…
Recent studies on T1-assisted MRI reconstruction for under-sampled images of other modalities have demonstrated the potential of further accelerating MRI acquisition of other modalities. Most of the state-of-the-art approaches have achieved…
We propose a deep learning-based approach that integrates MRI sequence parameters to improve the accuracy and generalizability of quantitative image synthesis from clinical weighted MRI. Our physics-driven neural network embeds MRI sequence…
The quality of fetal MRI is significantly affected by unpredictable and substantial fetal motion, leading to the introduction of artifacts even when fast acquisition sequences are employed. The development of 3D real-time fetal pose…
Fetal MRI is heavily constrained by unpredictable and substantial fetal motion that causes image artifacts and limits the set of viable diagnostic image contrasts. Current mitigation of motion artifacts is predominantly performed by fast,…
Parallel imaging is a commonly used technique to accelerate magnetic resonance imaging (MRI) data acquisition. Mathematically, parallel MRI reconstruction can be formulated as an inverse problem relating the sparsely sampled k-space…
While typical qualitative T1-weighted magnetic resonance images reflect scanner and protocol differences, quantitative T1 mapping aims to measure T1 independent of these effects. Changes in T1 in the brain reflect structural changes in…
Purpose: T2* quantification from gradient echo magnetic resonance imaging is particularly affected by subject motion due to the high sensitivity to magnetic field inhomogeneities, which are influenced by motion and might cause signal loss.…
Longitudinal fetal brain atlas is a powerful tool for understanding and characterizing the complex process of fetus brain development. Existing fetus brain atlases are typically constructed by averaged brain images on discrete time points…
Hippocampal subfield segmentation requires high-resolution T2w turbo spin echo (TSE) MRI, yet this sequence is susceptible to motion artifacts, leading to substantial data loss. We developed a conditional generative model (MRecover) that…
Quantitative T1rho mapping has shown promise in clinical and research studies. However, it suffers from long scan times. Deep learning-based techniques have been successfully applied in accelerated quantitative MR parameter mapping.…
Ultra-high resolution 7 tesla (7T) magnetic resonance imaging (MRI) provides detailed anatomical views, offering better signal-to-noise ratio, resolution and tissue contrast than 3T MRI, though at the cost of accessibility. We present an…
Magnetic resonance imaging (MRI) is a crucial medical imaging modality. However, long acquisition times remain a significant challenge, leading to increased costs, and reduced patient comfort. Recent studies have shown the potential of…
Purpose: This study demonstrated an MR signal multitask learning method for 3D simultaneous segmentation and relaxometry of human brain tissues. Materials and Methods: A 3D inversion-prepared balanced steady-state free precession sequence…
Fetal brain MRI is becoming an increasingly relevant complement to neurosonography for perinatal diagnosis, allowing fundamental insights into fetal brain development throughout gestation. However, uncontrolled fetal motion and…