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Related papers: Exploring Quantum Annealing for Coarse-Grained Pro…

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We review theoretical approaches, experiments and numerical simulations that have been recently proposed to investigate the folding problem in single-domain proteins. From a theoretical point of view, we emphasize the energy landscape…

Biological Physics · Physics 2008-10-20 Ivan Junier , Felix Ritort

In this work we investigate the capabilities of a hybrid quantum-classical procedure to explore the solution space using the D-Wave $2000Q^{TM}$ Quantum Annealer device. Here we study the ability of the Quantum hardware to solve the Number…

Quantum Physics · Physics 2020-03-10 Luca Asproni , Davide Caputo , Blanca Silva , Giovanni Fazzi , Marco Magagnini

Quantum phenomena have the potential to speed up the solution of hard optimization problems. For example quantum annealing, based on the quantum tunneling effect, has recently been shown to scale exponentially better with system size as…

Quantum Physics · Physics 2017-04-27 Simon E. Nigg , Niels Loerch , Rakesh P. Tiwari

Owing to the computational complexity of electronic structure algorithms running on classical digital computers, the range of molecular systems amenable to simulation remains tightly circumscribed even after many decades of work. Quantum…

Quantum Physics · Physics 2022-05-18 Alexis Ralli , Michael I. Williams , Peter V. Coveney

The utility of satisfiability (SAT) as an application focused hard computational problem is well established. We explore the potential of quantum annealing to enhance classical SAT solving, especially where sampling from the space of all…

Quantum Physics · Physics 2016-12-22 Kristen L. Pudenz , Gregory S. Tallant , Todd R. Belote , Steven H. Adachi

Advances in quantum algorithms suggest a tentative scaling advantage on certain combinatorial optimization problems. Recent work, however, has also reinforced the idea that barren plateaus render variational algorithms ineffective on large…

Quantum Physics · Physics 2025-03-14 Tim Bode , Krish Ramesh , Tobias Stollenwerk

We propose a modified MSA algorithm on quantum annealers with applications in areas of bioinformatics and genetic sequencing. To understand the human genome, researchers compare extensive sets of these genetic sequences -- or their protein…

Quantum Physics · Physics 2024-03-28 Melody Lee

The application of quantum annealing to the optimization of continuous-variable functions is a relatively unexplored area of research. We test the performance of quantum annealing applied to a one-dimensional continuous-variable function…

Quantum Physics · Physics 2023-10-06 Shunta Arai , Hiroki Oshiyama , Hidetoshi Nishimori

Quantum annealers are an alternative approach to quantum computing which make use of the adiabatic theorem to efficiently find the ground state of a physically realizable Hamiltonian. Such devices are currently commercially available and…

Quantum Physics · Physics 2021-02-24 Justin Copenhaver , Adam Wasserman , Birgit Wehefritz-Kaufmann

This work focuses on quantum methods for cryptanalysis of schemes based on the integer factorization problem and the discrete logarithm problem. We demonstrate how to practically solve the largest instances of the factorization problem by…

Cryptography and Security · Computer Science 2024-10-08 Olgierd Żołnierczyk

Quantum annealers are specialized quantum computers for solving combinatorial optimization problems using special characteristics of quantum computing (QC), such as superposition, entanglement, and quantum tunneling. Theoretically, quantum…

Software Engineering · Computer Science 2024-07-29 Xinyi Wang , Asmar Muqeet , Tao Yue , Shaukat Ali , Paolo Arcaini

Quantum annealing aims at solving optimization problems efficiently by preparing the ground state of an Ising spin-Hamiltonian quantum mechanically. A prerequisite of building a quantum annealer is the implementation of programmable…

Quantum Gases · Physics 2020-11-10 Xingze Qiu , Peter Zoller , Xiaopeng Li

Quantum Annealing, or Quantum Stochastic Optimization, is a classical randomized algorithm which provides good heuristics for the solution of hard optimization problems. The algorithm, suggested by the behaviour of quantum systems, is an…

Quantum Physics · Physics 2011-07-06 Diego de Falco , Dario Tamascelli

Recently, Lechner, Hauke and Zoller [Science Advances, 1(9)e1500838, (2015)] have proposed a quantum annealing architecture, in which a classical spin glass with all-to-all connectivity is simulated by a spin glass with geometrically local…

Quantum Physics · Physics 2016-05-25 Fernando Pastawski , John Preskill

Over the past decade, the usefulness of quantum annealing hardware for combinatorial optimization has been the subject of much debate. Thus far, experimental benchmarking studies have indicated that quantum annealing hardware does not…

Optimization and Control · Mathematics 2022-10-11 Byron Tasseff , Tameem Albash , Zachary Morrell , Marc Vuffray , Andrey Y. Lokhov , Sidhant Misra , Carleton Coffrin

Quantum annealing approximately solves combinatorial optimization problems by leveraging the principles of adiabatic quantum systems. In this approach, the system's Hamiltonian evolves from an initial general state to a problem-specific…

NP-hard optimization problems scale very rapidly with problem size, becoming unsolvable with brute force methods, even with supercomputing resources. Typically, such problems have been approximated with heuristics. However, these methods…

Quantum Physics · Physics 2018-03-21 Gideon Bass , Casey Tomlin , Vaibhaw Kumar , Pete Rihaczek , Joseph Dulny

Quantum machine learning is one of the fields where quantum computers are expected to bring advantages over classical methods. However, the limited size of current computers restricts the exploitation of the full potential of quantum…

Quantum Physics · Physics 2025-11-10 Juan C. Boschero , Ward van der Schoot , Niels M. P. Neumann

Recent advances bring within reach the viability of solving combinatorial problems using a quantum annealing algorithm implemented on a purpose-built platform that exploits quantum properties. However, the question of how to tune the…

Data Structures and Algorithms · Computer Science 2014-10-21 Andrew D. King , Catherine C. McGeoch

Mainstream machine-learning techniques such as deep learning and probabilistic programming rely heavily on sampling from generally intractable probability distributions. There is increasing interest in the potential advantages of using…

Quantum Physics · Physics 2018-01-29 Marcello Benedetti , John Realpe-Gómez , Rupak Biswas , Alejandro Perdomo-Ortiz