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A major limitation of current generations of quantum annealers is the sparse connectivity of manufactured qubits in the hardware graph. This technological limitation generated considerable interest, motivating efforts to design efficient…

Quantum annealing provides a powerful platform for simulating magnetic materials and realizing statistical physics models, presenting a compelling alternative to classical Monte Carlo methods. We demonstrate that quantum annealers can…

We evaluate the application of quantum annealing (QA) to a real-world combinatorial optimisation problem-room scheduling for sports camps at the Australian Institute of Sport-using both classical and quantum approaches. Due to current…

Quantum Physics · Physics 2025-09-08 Krzysztof Giergiel , Y. Sam Yang , Anthony B. Murphy

We address the problem of checking query containment, a foundational problem in database research. Although extensively studied in theory research, optimization opportunities arising from query containment are not fully leveraged in…

Databases · Computer Science 2026-03-17 Luisa Gerlach , Tobias Köppl , René Zander , Nicole Schweikardt , Stefanie Scherzinger

Motivated by recent progress in quantum hardware and algorithms researchers have developed quantum heuristics for optimization problems, aiming for advantages over classical methods. To date, quantum hardware is still error-prone and…

Quantum Physics · Physics 2026-04-27 Friedrich Wagner , Frauke Liers

Diagnosing the minimal set of faults capable of explaining a set of given observations, e.g., from sensor readouts, is a hard combinatorial optimization problem usually tackled with artificial intelligence techniques. We present the mapping…

Achieving densely connected hardware graphs is a challenge for most quantum computing platforms today, and a particularly crucial one for the case of quantum annealing applications. In this context, we present a scalable architecture for…

Quantum Physics · Physics 2025-06-02 Ana Palacios , Artur Garcia-Saez , Bruno Julia-Diaz , Marta P. Estarellas

Many researches have been working on the protein folding problem from more than half century. Protein folding is indeed one of the major unsolved problems in science. In this work, we discuss a model for the simulation of protein…

Optimization and Control · Mathematics 2008-11-20 A. Mucherino , O. Seref , P. M. Pardalos

The application in cryptography of quantum algorithms for prime factorization fostered the interest in quantum computing. However, quantum computers, and particularly quantum annealers, can also be helpful to construct secure cryptographic…

Quantum Physics · Physics 2021-01-27 Feng Hu , Lucas Lamata , Chao Wang , Xi Chen , Enrique Solano , Mikel Sanz

Deep learning models are used in critical applications, in which mistakes can have serious consequences. Therefore, it is crucial to understand how and why models generate predictions. This understanding provides useful information to check…

Quantum annealing is an innovative idea and method for avoiding the increase of the calculation cost of the combinatorial optimization problem. Since the combinatorial optimization problems are ubiquitous, quantum annealing machine with…

Statistical Mechanics · Physics 2020-01-13 Shohei Watabe , Yuya Seki , Shiro Kawabata

Quantum annealing is a promising algorithm for solving combinatorial optimization problems. However, various hardware restrictions significantly impede its efficient performance. Size-reduction methods provide an effective approach for…

Statistical Mechanics · Physics 2025-07-22 Tomohiro Hattori , Hirotaka Irie , Tadashi Kadowaki , Shu Tanaka

Optimizing the training of a machine learning pipeline helps in reducing training costs and improving model performance. One such optimizing strategy is quantum annealing, which is an emerging computing paradigm that has shown potential in…

Quantum Physics · Physics 2021-06-08 Rajdeep Kumar Nath , Himanshu Thapliyal , Travis S. Humble

We introduce a novel approach to solving dynamic programming problems, such as those in many economic models, on a quantum annealer, a specialized device that performs combinatorial optimization. Quantum annealers attempt to solve an…

General Economics · Economics 2023-06-08 Jesús Fernández-Villaverde , Isaiah Hull

In this paper we show quantum fluctuation effect of fully frustrated Ising spin systems. Quantum annealing has been expected to be an efficient method to find ground state of optimization problems. However it is not clear when to use the…

Disordered Systems and Neural Networks · Physics 2011-06-06 Shu Tanaka

This study introduces a novel framework that brings together two main Quantum Programming methodologies, gate-based Quantum Computing and Quantum Annealing, by applying the Model-Driven Engineering principles. This aims to enhance the…

Quantum Physics · Physics 2024-10-14 Furkan Polat , Hasan Tuncer , Armin Moin , Moharram Challenger

In spite of decades of research, much remains to be discovered about folding: the detailed structure of the initial (unfolded) state, vestigial folding instructions remaining only in the unfolded state, the interaction of the molecule with…

Biological Physics · Physics 2018-11-26 Walter A. Simmons

Quantum Annealing (QA) is one of the most promising frameworks for quantum optimization. Here, we focus on the problem of minimizing complex classical cost functions associated with prototypical discrete neural networks, specifically the…

Quantum Physics · Physics 2023-05-17 Guglielmo Lami , Pietro Torta , Giuseppe E. Santoro , Mario Collura

We conduct an extensive study on using near-term quantum computers for a task in the domain of computational biology. By constructing quantum models based on parameterised quantum circuits we perform sequence classification on a task…

We propose Quantum Enhanced Simulated Annealing (QESA), a novel hybrid optimization framework that integrates quantum annealing (QA) into simulated annealing (SA) to tackle continuous optimization problems. While QA has shown promise in…

Quantum Physics · Physics 2025-04-04 Hristo N. Djidjev
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