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Semi-supervised image classification has shown substantial progress in learning from limited labeled data, but recent advances remain largely untested for clinical applications. Motivated by the urgent need to improve timely diagnosis of…

Computer Vision and Pattern Recognition · Computer Science 2021-08-03 Zhe Huang , Gary Long , Benjamin Wessler , Michael C. Hughes

Traditional deep learning models often lack annotated data, especially in cross-domain applications such as anomaly detection, which is critical for early disease diagnosis in medicine and defect detection in industry. To address this…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Wahyu Rahmaniar , Kenji Suzuki

Functional magnetic resonance imaging (fMRI) is a neuroimaging modality that captures the blood oxygen level in a subject's brain while the subject either rests or performs a variety of functional tasks under different conditions. Given…

Computer Vision and Pattern Recognition · Computer Science 2021-01-20 Sam Nguyen , Brenda Ng , Alan D. Kaplan , Priyadip Ray

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

Quantitative Methods · Quantitative Biology 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

Manual medical image segmentation is subjective and suffers from annotator-related bias, which can be mimicked or amplified by deep learning methods. Recently, researchers have suggested that such bias is the combination of the annotator…

Computer Vision and Pattern Recognition · Computer Science 2023-06-29 Zehui Liao , Yutong Xie , Shishuai Hu , Yong Xia

Synthesizing longitudinal medical images at controllable disease stages while preserving patient-specific anatomy is hindered by the entanglement of pathological textures and structural features. We address this challenge for ulcerative…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Umut Dundar , Alptekin Temizel

Learning discriminative representations for subtle localized details plays a significant role in Fine-grained Visual Categorization (FGVC). Compared to previous attention-based works, our work does not explicitly define or localize the part…

Computer Vision and Pattern Recognition · Computer Science 2022-10-18 Ranran Huang , Yu Wang , Huazhong Yang

Instance segmentation and classification of nuclei is an important task in computational pathology. We show that StarDist, a deep learning nuclei segmentation method originally developed for fluorescence microscopy, can be extended and…

Computer Vision and Pattern Recognition · Computer Science 2022-08-22 Martin Weigert , Uwe Schmidt

Virtual stain transfer is a promising area of research in Computational Pathology, which has a great potential to alleviate important limitations when applying deeplearningbased solutions such as lack of annotations and sensitivity to a…

Computer Vision and Pattern Recognition · Computer Science 2022-10-19 Jelica Vasiljević , Friedrich Feuerhake , Cédric Wemmert , Thomas Lampert

The rapid on-site evaluation (ROSE) technique can significantly ac-celerate the diagnostic workflow of pancreatic cancer by immediately analyzing the fast-stained cytopathological images with on-site pathologists. Computer-aided diagnosis…

Image and Video Processing · Electrical Eng. & Systems 2022-06-08 Tianyi Zhang , Youdan Feng , Yunlu Feng , Guanglei Zhang

Histopathological image segmentation is a challenging and important topic in medical imaging with tremendous potential impact in clinical practice. State of the art methods rely on hand-crafted annotations which hinder clinical translation…

Accurate gross tumor volume segmentation on multi-modal medical data is critical for radiotherapy planning in nasopharyngeal carcinoma and glioblastoma. Recent advances in deep neural networks have brought promising results in medical image…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Jingyun Yang , Guoqing Zhang , Jingge Wang , Yang Li

In the intelligent diagnosis of bimodal (gray-scale and contrast-enhanced) ultrasound videos, medical domain knowledge such as the way sonographers browse videos, the particular areas they emphasize, and the features they pay special…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Chengqian Zhao , Zhao Yao , Zhaoyu Hu , Yuanxin Xie , Yafang Zhang , Yuanyuan Wang , Shuo Li , Jianhua Zhou , Jianqiao Zhou , Yin Wang , Jinhua Yu

Thyroid cancer is among the most common cancers in the United States. Thyroid nodules are frequently detected through ultrasound (US) imaging, and some require further evaluation via fine-needle aspiration (FNA) biopsy. Despite its…

We developed a deep learning framework that helps to automatically identify and segment lung cancer areas in patients' tissue specimens. The study was based on a cohort of lung cancer patients operated at the Uppsala University Hospital.…

Computer Vision and Pattern Recognition · Computer Science 2018-07-30 Nikolay Burlutskiy , Feng Gu , Lena Kajland Wilen , Max Backman , Patrick Micke

Melanoma brain metastases (MBM) are common and spatially heterogeneous lesions, complicating cohort-level analyses due to anatomical variability and differing MRI protocols. We propose a fully differentiable, deep-learning-based deformable…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Nanna E. Wielenberg , Ilinca Popp , Oliver Blanck , Lucas Zander , Jan C. Peeken , Stephanie E. Combs , Anca-Ligia Grosu , Dimos Baltas , Tobias Fechter

Nowadays, navigation and ride-sharing apps have collected numerous images with spatio-temporal data. A core technology for analyzing such images, associated with spatiotemporal information, is Traffic Scene Understanding (TSU), which aims…

Multimedia · Computer Science 2025-11-13 Jingtian Ma , Jingyuan Wang , Wayne Xin Zhao , Guoping Liu , Xiang Wen

Expression of human epidermal growth factor receptor 2 (HER2) is an important biomarker in breast cancer patients who can benefit from cost-effective automatic Hematoxylin and Eosin (H\&E) HER2 scoring. However, developing such scoring…

Computer Vision and Pattern Recognition · Computer Science 2024-11-11 Rawan S. Abdulsadig , Bryan M. Williams , Nikolay Burlutskiy

Pathologists find tedious to examine the status of the sentinel lymph node on a large number of pathological scans. The examination process of such lymph node which encompasses metastasized cancer cells is histopathologically organized.…

Computer Vision and Pattern Recognition · Computer Science 2019-06-25 Amit Kumar Jaiswal , Ivan Panshin , Dimitrij Shulkin , Nagender Aneja , Samuel Abramov

While pathology foundation models have transformed cancer image analysis, they often lack integration with molecular data at single-cell resolution, limiting their utility for precision oncology. Here, we present PAST, a pan-cancer…

Quantitative Methods · Quantitative Biology 2025-07-10 Changchun Yang , Haoyang Li , Yushuai Wu , Yilan Zhang , Yifeng Jiao , Yu Zhang , Rihan Huang , Yuan Cheng , Yuan Qi , Xin Guo , Xin Gao