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Lung cancer is an extremely lethal disease primarily due to its late-stage diagnosis and significant mortality rate, making it the major cause of cancer-related demises globally. Machine Learning (ML) and Convolution Neural network (CNN)…

Image and Video Processing · Electrical Eng. & Systems 2025-01-03 Asha V , Bhavanishankar K

Performance of data-driven network for tumor classification varies with stain-style of histopathological images. This article proposes the stain-style transfer (SST) model based on conditional generative adversarial networks (GANs) which is…

Computer Vision and Pattern Recognition · Computer Science 2018-12-21 Hyungjoo Cho , Sungbin Lim , Gunho Choi , Hyunseok Min

Even though convolutional neural networks (CNNs) are driving progress in medical image segmentation, standard models still have some drawbacks. First, the use of multi-scale approaches, i.e., encoder-decoder architectures, leads to a…

Computer Vision and Pattern Recognition · Computer Science 2020-02-18 Ashish Sinha , Jose Dolz

Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

Whole-Slide Imaging allows for the capturing and digitization of high-resolution images of histological specimen. An automated analysis of such images using deep learning models is therefore of high demand. The transformer architecture has…

Computer Vision and Pattern Recognition · Computer Science 2023-05-12 Firas Khader , Jakob Nikolas Kather , Tianyu Han , Sven Nebelung , Christiane Kuhl , Johannes Stegmaier , Daniel Truhn

The expanding ecosystem of pathology foundation models has produced powerful but fragmented tile-level representations, limiting their use in clinical tasks that require unified slide-level reasoning and interpretable linkage to clinically…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Tianyang Wang , Ziyu Su , Abdul Rehman Akbar , Usama Sajjad , Lina Gokhale , Charles Rabolli , Wei Chen , Anil Parwani , Muhammad Khalid Khan Niazi

The efficacy of deep learning-based Computer-Aided Diagnosis (CAD) methods for skin diseases relies on analyzing multiple data modalities (i.e., clinical+dermoscopic images, and patient metadata) and addressing the challenges of multi-label…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Yuan Zhang , Yutong Xie , Hu Wang , Jodie C Avery , M Louise Hull , Gustavo Carneiro

Unsupervised multivariate time series anomaly detection (UMTSAD) plays a critical role in various domains, including finance, networks, and sensor systems. In recent years, due to the outstanding performance of deep learning in general…

Machine Learning · Computer Science 2025-04-28 Tiange Huang , Yongjun Li

The goal of video anomaly detection is tantamount to performing spatio-temporal localization of abnormal events in the video. The multiscale temporal dependencies, visual-semantic heterogeneity, and the scarcity of labeled data exhibited by…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Dezhi An , Wenqiang Liu , Kefan Wang , Zening Chen , Jun Lu , Shengcai Zhang

Acquiring high-quality instance segmentation data is challenging due to the labor-intensive nature of the annotation process and significant class imbalances within datasets. Recent studies have utilized the integration of Copy-Paste and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Xianbao Hou , Yonghao He , Zeyd Boukhers , John See , Hu Su , Wei Sui , Cong Yang

The recent advancement of spatial transcriptomics (ST) allows to characterize spatial gene expression within tissue for discovery research. However, current ST platforms suffer from low resolution, hindering in-depth understanding of…

Image and Video Processing · Electrical Eng. & Systems 2025-11-05 Xiaofei Wang , Xingxu Huang , Stephen J. Price , Chao Li

Spatial transcriptomics (ST) enables gene expression mapping within anatomical context but remains costly and low-throughput. Hematoxylin and eosin (H\&E) staining offers rich morphology yet lacks molecular resolution. We present…

Diagnostic investigation has an important role in risk stratification and clinical decision making of patients with suspected and documented Coronary Artery Disease (CAD). However, the majority of existing tools are primarily focused on the…

Accurate tumor staging in lung cancer is crucial for prognosis and treatment planning and is governed by explicit anatomical criteria under fixed guidelines. However, most existing deep learning approaches treat this spatially structured…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Saniah Kayenat Chowdhury , Rusab Sarmun , Muhammad E. H. Chowdhury , Sohaib Bassam Zoghoul , Israa Al-Hashimi , Adam Mushtak , Amith Khandakar

Medical image classification is a core task in computer-aided diagnosis (CAD), playing a pivotal role in early disease detection, treatment planning, and patient prognosis assessment. In ophthalmic practice, fluorescein fundus angiography…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Zhuonan Wang , Wenjie Yan , Wenqiao Zhang , Xiaohui Song , Jian Ma , Ke Yao , Yibo Yu , Beng Chin Ooi

Lung adenocarcinoma is a morphologically heterogeneous disease, characterized by five primary histologic growth patterns. The quantity of these patterns can be related to tumor behavior and has a significant impact on patient prognosis. In…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Arwa Al-Rubaian , Gozde N. Gunesli , Wajd A. Althakfi , Ayesha Azam , Nasir Rajpoot , Shan E Ahmed Raza

Long-context understanding is crucial for many NLP applications, yet transformers struggle with efficiency due to the quadratic complexity of self-attention. Sparse attention methods alleviate this cost but often impose static, predefined…

Computation and Language · Computer Science 2025-06-16 Hanzhi Zhang , Heng Fan , Kewei Sha , Yan Huang , Yunhe Feng

Anomaly detection in medical images is a challenging task, since anomalies are not typically available during training. Recent methods leverage a single pretext task coupled with a large-scale pre-trained model to reach state-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Bogdan Alexandru Bercean , Florinel Alin Croitoru , Vlad Hondru , Ciprian Mihai Ceausescu , Andreea Iuliana Ionescu , Radu Tudor Ionescu

Whole-slide image classification represents a key challenge in computational pathology and medicine. Attention-based multiple instance learning (MIL) has emerged as an effective approach for this problem. However, the effect of attention…

Quantitative Methods · Quantitative Biology 2025-03-14 Rajiv Krishnakumar , Julien Baglio , Frederik F. Flöther , Christian Ruiz , Stefan Habringer , Nicole H. Romano

Cancer pathological analysis requires modeling tumor heterogeneity across multiple modalities, primarily through transcriptomics and whole slide imaging (WSI), along with their spatial relations. On one hand, bulk transcriptomics and WSI…

Machine Learning · Computer Science 2026-03-17 Jingkun Yu , Guangkai Shang , Changtao Li , Xun Gong , Tianrui Li , Yazhou He , Zhipeng Luo
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