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Objective: This article presents an automatic image processing framework to extract quantitative high-level information describing the micro-environment of glomeruli in consecutive whole slide images (WSIs) processed with different staining…

Computer Vision and Pattern Recognition · Computer Science 2021-05-04 Odyssee Merveille , Thomas Lampert , Jessica Schmitz , Germain Forestier , Friedrich Feuerhake , Cédric Wemmert

In the era of foundation models, fine-tuning pre-trained models for specific downstream tasks has become crucial. This drives the need for robust fine-tuning methods to address challenges such as model overfitting and sparse labeling.…

Machine Learning · Computer Science 2025-12-12 Shikun Liu , Deyu Zou , Nima Shoghi , Victor Fung , Kai Liu , Pan Li

Current artificial intelligence models for medical imaging are predominantly single modality and single disease. Attempts to create multimodal and multi-disease models have resulted in inconsistent clinical accuracy. Furthermore, training…

Intelligent transportation systems (ITS) localization is of significant importance as it provides fundamental position and orientation for autonomous operations like intelligent vehicles. Integrating diverse and complementary sensors such…

Robotics · Computer Science 2024-09-20 Wei Liu , Jiaqi Zhu , Guirong Zhuo , Wufei Fu , Zonglin Meng , Yishi Lu , Min Hua , Feng Qiao , You Li , Yi He , Lu Xiong

Super-resolution ultrasound via microbubble (MB) localisation and tracking, also known as ultrasound localisation microscopy (ULM), can resolve microvasculature beyond the acoustic diffraction limit. However, significant challenges remain…

The integration of deep learning in medical imaging has shown great promise for enhancing diagnostic, therapeutic, and research outcomes. However, applying universal models across multiple modalities remains challenging due to the inherent…

Image and Video Processing · Electrical Eng. & Systems 2024-12-30 Yixin Chen , Lin Gao , Yajuan Gao , Rui Wang , Jingge Lian , Xiangxi Meng , Yanhua Duan , Leiying Chai , Hongbin Han , Zhaoping Cheng , Zhaoheng Xie

Recognition of glomeruli lesions is the key for diagnosis and treatment planning in kidney pathology; however, the coexisting glomerular structures such as mesangial regions exacerbate the difficulties of this task. In this paper, we…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Yang Nan , Fengyi Li , Peng Tang , Guyue Zhang , Caihong Zeng , Guotong Xie , Zhihong Liu , Guang Yang

Fine-grained glomerular subtyping is central to kidney biopsy interpretation, but clinically valuable labels are scarce and difficult to obtain. Existing computational pathology approaches instead tend to evaluate coarse diseased…

The integration of AI-assisted biomedical image analysis into clinical practice demands AI-generated findings that are not only accurate but also interpretable to clinicians. However, existing biomedical AI models generally lack the ability…

Accurate and interpretable prediction of estimated glomerular filtration rate (eGFR) is essential for managing chronic kidney disease (CKD) and supporting clinical decisions. Recent advances in Large Multimodal Models (LMMs) have shown…

Machine Learning · Computer Science 2025-07-31 Peng-Yi Wu , Pei-Cing Huang , Ting-Yu Chen , Chantung Ku , Ming-Yen Lin , Yihuang Kang

We address the problem of glass surface segmentation with an RGB-D camera, with a focus on effectively fusing RGB and depth information. To this end, we propose a Weighted Feature Fusion (WFF) module that dynamically and adaptively combines…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Henghong Lin , Zihan Zhu , Tao Wang , Anastasia Ioannou , Yuanshui Huang

Electroencephalography (EEG) signals provide critical insights for applications in disease diagnosis and healthcare. However, the scarcity of labeled EEG data poses a significant challenge. Foundation models offer a promising solution by…

Machine Learning · Computer Science 2025-02-25 Limin Wang , Toyotaro Suzumura , Hiroki Kanezashi

Recent advancements in deep models have highlighted the need for intelligent systems that combine continual learning (CL) for knowledge acquisition with machine unlearning (MU) for data removal, forming the Continual Learning-Unlearning…

Machine Learning · Computer Science 2025-05-22 Zhehao Huang , Xinwen Cheng , Jie Zhang , Jinghao Zheng , Haoran Wang , Zhengbao He , Tao Li , Xiaolin Huang

The Genomic Foundation Model (GFM) paradigm is expected to facilitate the extraction of generalizable representations from massive genomic data, thereby enabling their application across a spectrum of downstream applications. Despite…

Genomics · Quantitative Biology 2024-06-06 Zicheng Liu , Jiahui Li , Siyuan Li , Zelin Zang , Cheng Tan , Yufei Huang , Yajing Bai , Stan Z. Li

Machine learning (ML) methods have the potential to automate clinical EEG analysis. They can be categorized into feature-based (with handcrafted features), and end-to-end approaches (with learned features). Previous studies on EEG pathology…

Accurate detection and segmentation of glomeruli in kidney tissue are essential for diagnostic applications. Traditional deep learning methods primarily rely on semantic segmentation, which often fails to precisely delineate adjacent…

Tissues and Organs · Quantitative Biology 2026-04-17 Behnaz Elhaminia , Catherine King , Jiaqi Lv , Lorraine Harper , Paul Moss , Owen Cain , Dimitrios Chanouzas , Shan E Ahmed Raza

The great potential of unsupervised monocular depth estimation has been demonstrated by many works due to low annotation cost and impressive accuracy comparable to supervised methods. To further improve the performance, recent works mainly…

Computer Vision and Pattern Recognition · Computer Science 2023-02-08 Junyu Zhu , Lina Liu , Yong Liu , Wanlong Li , Feng Wen , Hongbo Zhang

Multimodal medical analysis combining image and tabular data has gained increasing attention. However, effective fusion remains challenging due to cross-modal discrepancies in feature dimensions and modality contributions, as well as the…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Congjing Yu , Jing Ye , Yang Liu , Xiaodong Zhang , Zhiyong Zhang

Background: This research aims to improve glioblastoma survival prediction by integrating MR images, clinical and molecular-pathologic data in a transformer-based deep learning model, addressing data heterogeneity and performance…

This study introduces the Hybrid Multi-modal VGG (HM-VGG) model, a cutting-edge deep learning approach for the early diagnosis of glaucoma. The HM-VGG model utilizes an attention mechanism to process Visual Field (VF) data, enabling the…

Image and Video Processing · Electrical Eng. & Systems 2024-11-01 Junliang Du , Yiru Cang , Tong Zhou , Jiacheng Hu , Weijie He