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Motivated by the emerging needs of personalized preventative intervention in many healthcare applications, we consider a multi-stage, dynamic decision-making problem in the online setting with unknown model parameters. To deal with the…

Machine Learning · Computer Science 2022-11-17 Xinyun Chen , Pengyi Shi , Shanwen Pu

Dynamic Treatment Regimes (DTRs) provide a systematic framework for optimizing sequential decision-making in chronic disease management, where therapies must adapt to patients' evolving clinical profiles. Inverse probability weighting (IPW)…

Methodology · Statistics 2026-03-26 Chloe Si , David A. Stephens , Erica E. M. Moodie

Randomized clinical trials are the gold standard when estimating the average treatment effect. However, they are usually not a random sample from the real-world population because of the inclusion/exclusion rules. Meanwhile, observational…

Methodology · Statistics 2024-12-11 Kuan Jiang , Wenjie Hu , Shu Yang , Xinxing Lai , Xiaohua Zhou

We develop an analytical synthesis that bridges data-driven Distributionally Robust Optimization (DRO) and Economic Decision Theory under Ambiguity (DTA). By reinterpreting standard regularization and DRO techniques as data-driven…

Machine Learning · Statistics 2025-02-27 Nicola Bariletto , Khai Nguyen , Nhat Ho

Combination drug therapies hold significant promise for enhancing treatment efficacy, particularly in fields such as oncology, immunotherapy, and infectious diseases. However, designing clinical trials for these regimens poses unique…

Methodology · Statistics 2025-06-04 Nan Miles Xi , Man Mandy Jin , Lin Wang , Xin Huang

Dynamic treatment regimens (DTRs), also known as treatment algorithms or adaptive interventions, play an increasingly important role in many health domains. DTRs are motivated to address the unique and changing needs of individuals by…

Dataset distillation (DD) aims to construct compact synthetic datasets that allow models to achieve comparable performance to full-data training while substantially reducing storage and computation. Despite rapid empirical progress, its…

Machine Learning · Computer Science 2025-12-11 Zhengquan Luo , Zhiqiang Xu

Autonomous navigation in intelligent mobile systems represents a core research focus within artificial intelligence-driven robotics. Contemporary path planning approaches face constraints in dynamic environmental responsiveness and…

Robotics · Computer Science 2025-03-11 Junzhe Wang

A dynamic treatment regimen (DTR) is a pre-specified sequence of decision rules which maps baseline or time-varying measurements on an individual to a recommended intervention or set of interventions. Sequential multiple assignment…

Methodology · Statistics 2019-10-23 Brook Luers , Min Qian , Inbal Nahum-Shani , Connie Kasari , Daniel Almirall

Randomized Controlled Trials (RCTs), or A/B testing, have become the gold standard for optimizing various operational policies on online platforms. However, RCTs on these platforms typically cover a limited number of discrete treatment…

Econometrics · Economics 2026-02-06 Zhiqi Zhang , Zhiyu Zeng , Ruohan Zhan , Dennis Zhang

Randomized controlled trials (RCTs) are the gold standard for causal inference, yet practical constraints often limit the size of the concurrent control arm. Borrowing control data from previous trials offers a potential efficiency gain,…

Methodology · Statistics 2026-03-17 Linying Yang , Xing Liu , Robin J. Evans

In some practical learning tasks, such as traffic video analysis, the number of available training samples is restricted by different factors, such as limited communication bandwidth and computation power. Determinantal Point Process (DPP)…

Machine Learning · Computer Science 2023-08-17 Xiwen Chen , Huayu Li , Rahul Amin , Abolfazl Razi

Establishing causality is a fundamental goal in fields like medicine and social sciences. While randomized controlled trials are the gold standard for causal inference, they are not always feasible or ethical. Observational studies can…

Statistics Theory · Mathematics 2024-12-03 Andrew Ying

A main research goal in various studies is to use an observational data set and provide a new set of counterfactual guidelines that can yield causal improvements. Dynamic Treatment Regimes (DTRs) are widely studied to formalize this…

Machine Learning · Computer Science 2023-06-06 Soroush Saghafian

Distribution Matching Distillation (DMD) facilitates efficient inference by distilling multi-step diffusion models into few-step variants. Concurrently, Reinforcement Learning (RL) has emerged as a vital tool for aligning generative models…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Dengyang Jiang , Dongyang Liu , Zanyi Wang , Qilong Wu , Liuzhuozheng Li , Hengzhuang Li , Xin Jin , David Liu , Changsheng Lu , Zhen Li , Bo Zhang , Mengmeng Wang , Steven Hoi , Peng Gao , Harry Yang

Experiments on online marketplaces and social networks suffer from interference, where the outcome of a unit is impacted by the treatment status of other units. We propose a framework for modeling interference using a ubiquitous deployment…

Methodology · Statistics 2023-08-21 Ariel Boyarsky , Hongseok Namkoong , Jean Pouget-Abadie

Dynamic treatment regimes (DTRs) provide a principled framework for optimizing sequential decision-making in domains where decisions must adapt over time in response to individual trajectories, such as healthcare, education, and digital…

Machine Learning · Statistics 2026-01-30 Ruijia Zhang , Xiangyu Zhang , Zhengling Qi , Yue Wu , Yanxun Xu

Reinforcement learning (RL) has garnered increasing recognition for its potential to optimise dynamic treatment regimes (DTRs) in personalised medicine, particularly for drug dosage prescriptions and medication recommendations. However, a…

Machine Learning · Computer Science 2024-05-30 Zhiyao Luo , Mingcheng Zhu , Fenglin Liu , Jiali Li , Yangchen Pan , Jiandong Zhou , Tingting Zhu

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

Dataset distillation (DD) has emerged as a widely adopted technique for crafting a synthetic dataset that captures the essential information of a training dataset, facilitating the training of accurate neural models. Its applications span…

Machine Learning · Computer Science 2025-02-04 Saeed Vahidian , Mingyu Wang , Jianyang Gu , Vyacheslav Kungurtsev , Wei Jiang , Yiran Chen
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