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Phase separation plays an role in determining the self-assembly of biological and soft-matter systems. In biological systems, liquid-liquid phase separation inside a cell leads to the formation of various macromolecular aggregates. The…

Soft Condensed Matter · Physics 2024-03-26 Tanmay Biswas , Gerhard Kahl , Gaurav P. Shrivastav

We revisit motility-induced phase separation in two models of active particles interacting by pairwise repulsion. We show that the resulting dense phase contains gas bubbles distributed algebraically up to a typically large cutoff scale. At…

Statistical Mechanics · Physics 2021-01-27 Xia-qing Shi , Giordano Fausti , Hugues Chaté , Cesare Nardini , Alexandre Solon

Colloidal suspensions with free polymer coils which are larger than the colloidal particles are considered. The polymer-colloid interaction is modeled by an extension of the Asakura-Oosawa model. Phase separation occurs into dilute and…

Soft Condensed Matter · Physics 2009-10-31 Richard P. Sear

We study an active random walker model in which a particle's motion is determined by a self-generated field. The field encodes information about the particle's path history. This leads to either self-attractive or self-repelling behavior.…

Statistical Mechanics · Physics 2009-11-11 R. Grima

Flow transport in confined spaces is ubiquitous in technological processes, ranging from separation and purification of pharmaceutical ingredients by microporous membranes and drug delivery in biomedical treatment to chemical and biomass…

Soft Condensed Matter · Physics 2021-01-01 Xuehua Zhang , Jae Bem You , Gilmar F. Arends , Jiasheng Qian , Yibo Chen , Detlef Lohse , John M. Shaw

We study the kinetic regime of the Bose-condensation of scalar particles with weak $\lambda \phi^4$ self-interaction. The Boltzmann equation is solved numerically. We consider two kinetic stages. At the first stage the condensate is still…

High Energy Physics - Phenomenology · Physics 2009-10-28 D. V. Semikoz , I. I. Tkachev

Non-aligning self-propelled particles with purely repulsive excluded volume interactions undergo athermal motility-induced phase separation into a dilute gas and a dense cluster phase. Here, we use enhanced sampling computational methods…

Soft Condensed Matter · Physics 2016-10-05 Gabriel S. Redner , Caleb G. Wagner , Aparna Baskaran , Michael F. Hagan

Many biological systems consist of self-motile and passive agents both of which contribute to overall functionality. However, there are very few studies of the properties of such mixtures. Here we formulate a model for mixtures of…

Soft Condensed Matter · Physics 2015-05-25 Denis F. Hinz , Alexander Panchenko , Tae-Yeon Kim , Eliot Fried

The more we learn about the cytoplasm of cells, the more we realise that the cytoplasm is not uniform but instead is highly inhomogeneous. In any inhomogeneous solution, there are concentration gradients, and particles move either up or…

Subcellular Processes · Quantitative Biology 2019-04-03 Richard P. Sear

Biomolecular condensates help organize the cell cytoplasm and nucleoplasm into spatial compartments with different chemical compositions. A key feature of such compositional patterning is the local enrichment of enzymatically active…

Biological Physics · Physics 2024-08-06 Andriy Goychuk , Leonardo Demarchi , Ivan Maryshev , Erwin Frey

In both biological and artificial systems, concentration gradients can serve as a convenient mechanism for manipulating particles and generating motility. Particles that interact with a solute will move along its gradient; if they…

Soft Condensed Matter · Physics 2011-07-21 Gareth P. Alexander , Andrea J. Liu

In this paper, we use the cell dynamics method to study the dynamics of phase transformation when three phases exist. The system we study is a two-dimensional system. The system is able to achieve three phases coexistence, which for…

Materials Science · Physics 2009-11-11 M. Iwamatsu

Spatially uniform electric fields have been used to induce instabilities in liquids and polymers, and to orient and deform ordered phases of block-copolymers. Here we discuss the demixing phase transition occurring in liquid mixtures when…

Statistical Mechanics · Physics 2015-05-13 G. Marcus , Y. Tsori

Motility and nonreciprocity are two primary mechanisms for self-organization in active matter. In a recent study [Phys. Rev. Lett. 131, 148301 (2023)], we explored their joint influence in a minimal model of two-species quorum-sensing…

Soft Condensed Matter · Physics 2025-04-15 Yu Duan , Jaime Agudo-Canalejo , Ramin Golestanian , Benoît Mahault

We show that dispersion in propulsion strength qualitatively alters collective behavior of active multi-particle systems interacting via short-range attractive potential, giving rise to novel ordered phases that combine spatial and…

Statistical Mechanics · Physics 2026-01-07 Debraj Dutta , Urna Basu

Biomolecular condensates are formed via liquid-liquid phase separation of proteins, often together with nucleic acids, typically driven by interactions between low-affinity binding sites. The computational study of such condensates that…

Soft Condensed Matter · Physics 2025-01-16 Alena Taskina , Devika Magan , Simon Dannenberg , Stefan Klumpp

We study a system of self-propelled disks that perform run-and-tumble motion, where particles can adopt more than one internal state. One of those internal states can be transmitted to another particle if the particle carrying this state…

Biological Physics · Physics 2019-12-30 Fernando Peruani , Gustavo Sibona

Inside every living cell is the cytoplasm: a fluid mixture of thousands of different macromolecules, predominantly proteins. This mixture is where most of the biochemistry occurs that enables living cells to function, and it is perhaps the…

Soft Condensed Matter · Physics 2009-11-11 Richard P. Sear

During the morphogenesis of tissues and tumors, cells often interact with neighbors with different mechanical properties, but the understanding of its role is lacking. We use active Brownian Dynamics simulations to study a model co-culture…

Soft Condensed Matter · Physics 2021-01-07 Supravat Dey , Moumita Das

Cells operate in part by compartmentalizing chemical reactions. For example, recent work has shown that chromatin, the material that contains the cell's genome, can auto-regulate its structure by utilizing reaction products (proteins, RNA)…

Soft Condensed Matter · Physics 2024-10-30 Sam Wilken , Gabrielle R. Abraham , Omar A. Saleh
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