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The opaque nature of Large Language Models (LLMs) has led to significant research efforts aimed at enhancing their interpretability, primarily through post-hoc methods. More recent in-hoc approaches, such as Concept Bottleneck Models…

Machine Learning · Computer Science 2025-02-20 Or Raphael Bidusa , Shaul Markovitch

Alzheimer's disease (AD) has become a prevalent neurodegenerative disease worldwide. Traditional diagnosis still relies heavily on medical imaging and clinical assessment by physicians, which is often time-consuming and resource-intensive…

Computation and Language · Computer Science 2026-02-17 Tongze Zhang , Jun-En Ding , Melik Ozolcer , Fang-Ming Hung , Albert Chih-Chieh Yang , Feng Liu , Yi-Rou Ji , Sang Won Bae

Depression poses significant challenges to patients and healthcare organizations, necessitating efficient assessment methods. Existing paradigms typically focus on a patient-doctor way that overlooks multi-role interactions, such as family…

Human-Computer Interaction · Computer Science 2026-03-10 Zhiyuan Zhou , Jilong Liu , Sanwang Wang , Shijie Hao , Yanrong Guo , Richang Hong

Concept Bottleneck Models (CBMs) ground image classification on human-understandable concepts to allow for interpretable model decisions. Crucially, the CBM design inherently allows for human interventions, in which expert users are given…

Machine Learning · Computer Science 2024-08-07 Nishad Singhi , Jae Myung Kim , Karsten Roth , Zeynep Akata

Appendicitis is among the most frequent reasons for pediatric abdominal surgeries. Previous decision support systems for appendicitis have focused on clinical, laboratory, scoring, and computed tomography data and have ignored abdominal…

Deep learning representations are often difficult to interpret, which can hinder their deployment in sensitive applications. Concept Bottleneck Models (CBMs) have emerged as a promising approach to mitigate this issue by learning…

Machine Learning · Computer Science 2026-01-30 Antonio Almudévar , José Miguel Hernández-Lobato , Alfonso Ortega

The lack of transparency in the decision-making processes of deep learning systems presents a significant challenge in modern artificial intelligence (AI), as it impairs users' ability to rely on and verify these systems. To address this…

Artificial Intelligence · Computer Science 2024-11-18 David Debot , Pietro Barbiero , Francesco Giannini , Gabriele Ciravegna , Michelangelo Diligenti , Giuseppe Marra

Passively collected behavioral health data from ubiquitous sensors holds significant promise to provide mental health professionals insights from patient's daily lives; however, developing analysis tools to use this data in clinical…

Black-box deep neural networks excel in text classification, yet their application in high-stakes domains is hindered by their lack of interpretability. To address this, we propose Text Bottleneck Models (TBM), an intrinsically…

Computation and Language · Computer Science 2024-04-04 Josh Magnus Ludan , Qing Lyu , Yue Yang , Liam Dugan , Mark Yatskar , Chris Callison-Burch

As AI models grow larger, the demand for accountability and interpretability has become increasingly critical for understanding their decision-making processes. Concept Bottleneck Models (CBMs) have gained attention for enhancing…

Machine Learning · Computer Science 2024-10-10 Angelos Ragkousis , Sonali Parbhoo

Deep learning models have achieved strong performance in medical image analysis, but their internal decision processes remain difficult to interpret. Concept Bottleneck Models (CBMs) partially address this limitation by structuring…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Getamesay Dagnaw , Xuefei Yin , Muhammad Hassan Maqsood , Yanming Zhu , Alan Wee-Chung Liew

Human cognition is constrained by processing limitations, leading to cognitive overload and inefficiencies in knowledge synthesis and decision-making. Large Language Models (LLMs) present an opportunity for cognitive augmentation, but their…

Human-Computer Interaction · Computer Science 2025-04-21 Xiangrong , Zhu , Yuan Xu , Tianjian Liu , Jingwei Sun , Yu Zhang , Xin Tong

There is growing interest in using machine learning (ML) to support clinical diagnosis, but most approaches rely on static, fully observed datasets and fail to reflect the sequential, resource-aware reasoning clinicians use in practice.…

Artificial Intelligence · Computer Science 2025-11-18 Silas Ruhrberg Estévez , Nicolás Astorga , Mihaela van der Schaar

Concept Bottleneck Models (CBMs) aim for ante-hoc interpretability by learning a bottleneck layer that predicts interpretable concepts before the decision. State-of-the-art approaches typically select which concepts to learn via human…

Machine Learning · Computer Science 2026-03-10 Antonio De Santis , Schrasing Tong , Marco Brambilla , Lalana Kagal

Concept Bottleneck Models (CBMs) are machine learning models that improve interpretability by grounding their predictions on human-understandable concepts, allowing for targeted interventions in their decision-making process. However, when…

In this study, we focus on automated approaches to detect depression from clinical interviews using multi-modal machine learning (ML). Our approach differentiates from other successful ML methods such as context-aware analysis through…

Machine Learning · Computer Science 2024-12-30 Genevieve Lam , Huang Dongyan , Weisi Lin

The acute respiratory distress syndrome (ARDS) is a severe form of hypoxemic respiratory failure with in-hospital mortality of 35-46%. High mortality is thought to be related in part to challenges in making a prompt diagnosis, which may in…

Machine Learning · Computer Science 2021-09-28 Gregory B. Rehm , Chao Wang , Irene Cortes-Puch , Chen-Nee Chuah , Jason Adams

General Multimodal Large Language Models (MLLMs) often underperform in capturing domain-specific nuances in medical diagnosis, trailing behind fully supervised baselines. Although fine-tuning provides a remedy, the high costs of expert…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Wenkai Zhao , Zipei Wang , Mengjie Fang , Di Dong , Jie Tian , Lingwei Zhang

Concept Bottleneck Models (CBMs) are regarded as inherently interpretable because they first predict a set of human-defined concepts which are used to predict a task label. For inherent interpretability to be fully realised, and ensure…

Machine Learning · Computer Science 2024-07-31 Jack Furby , Daniel Cunnington , Dave Braines , Alun Preece

Cognitive Diagnosis Models (CDMs) are designed to assess students' cognitive states by analyzing their performance across a series of exercises. However, existing CDMs often struggle with diagnosing infrequent students and exercises due to…

Artificial Intelligence · Computer Science 2025-02-11 Zhiang Dong , Jingyuan Chen , Fei Wu
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