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Gaussian Process (GP) models are widely utilized as surrogate models in scientific and engineering fields. However, standard GP models are limited to continuous variables due to the difficulties in establishing correlation structures for…

Machine Learning · Statistics 2025-03-05 Mingyu Pu , Songhao Wang , Haowei Wang , Szu Hui Ng

Generative Retrieval (GR) has emerged as a promising paradigm to unify indexing and search within a single probabilistic framework. However, existing approaches suffer from two intrinsic conflicts: (1) an Optimization Blockage, where the…

Information Retrieval · Computer Science 2026-03-12 Xujing Wang , Yufeng Chen , Boxuan Zhang , Jie Zhao , Chao Wei , Cai Xu , Ziyu Guan , Wei Zhao , Weiru Zhang , Xiaoyi Zeng

Generating novel active molecules for a given protein is an extremely challenging task for generative models that requires an understanding of the complex physical interactions between the molecule and its environment. In this paper, we…

We develop a novel, general and computationally efficient framework, called Divide and Conquer Dynamic Programming (DCDP), for localizing change points in time series data with high-dimensional features. DCDP deploys a class of greedy…

Methodology · Statistics 2023-06-05 Wanshan Li , Daren Wang , Alessandro Rinaldo

Distance metric learning can be viewed as one of the fundamental interests in pattern recognition and machine learning, which plays a pivotal role in the performance of many learning methods. One of the effective methods in learning such a…

Machine Learning · Computer Science 2020-02-21 Mostafa Razavi Ghods , Mohammad Hossein Moattar , Yahya Forghani

The prosperity of computer vision (CV) and natural language procession (NLP) in recent years has spurred the development of deep learning in many other domains. The advancement in machine learning provides us with an alternative option…

Machine Learning · Computer Science 2020-12-02 Chen Qian , Yunhai Xiong , Xiang Chen

For many computational problems involving randomness, intricate geometric features of the solution space have been used to rigorously rule out powerful classes of algorithms. This is often accomplished through the lens of the multi Overlap…

Computational Complexity · Computer Science 2023-02-14 David Gamarnik , Eren C. Kızıldağ , Will Perkins , Changji Xu

Belief Propagation (BP) is an important message-passing algorithm for various reasoning tasks over graphical models, including solving the Constraint Optimization Problems (COPs). It has been shown that BP can achieve state-of-the-art…

Artificial Intelligence · Computer Science 2022-09-27 Yanchen Deng , Shufeng Kong , Caihua Liu , Bo An

The area of geometry with its very strong and appealing visual contents and its also strong and appealing connection between the visual content and its formal specification, is an area where computational tools can enhance, in a significant…

Computational Geometry · Computer Science 2012-02-23 Vanda Santos , Pedro Quaresma

The analysis of the three-dimensional structure of proteins is an important topic in molecular biochemistry. Structure plays a critical role in defining the function of proteins and is more strongly conserved than amino acid sequence over…

Applications · Statistics 2015-01-19 Abel Rodriguez , Scott C. Schmidler

We present a series of new differentially private (DP) algorithms with dimension-independent margin guarantees. For the family of linear hypotheses, we give a pure DP learning algorithm that benefits from relative deviation margin…

Machine Learning · Computer Science 2022-04-25 Raef Bassily , Mehryar Mohri , Ananda Theertha Suresh

Random backpropagation (RBP) is a variant of the backpropagation algorithm for training neural networks, where the transpose of the forward matrices are replaced by fixed random matrices in the calculation of the weight updates. It is…

Machine Learning · Computer Science 2017-12-25 Pierre Baldi , Peter Sadowski , Zhiqin Lu

In the NP-hard continuous 1.5D Terrain Guarding Problem (TGP) we are given an $x$-monotone chain of line segments in $\mathbb{R}^2$ (the terrain $T$) and ask for the minimum number of guards (located anywhere on $T$) required to guard all…

Computational Geometry · Computer Science 2016-06-28 Stephan Friedrichs , Michael Hemmer , James King , Christiane Schmidt

This paper presents a computationally efficient yet powerful binary framework for robust facial representation based on image gradients. It is termed as structural binary gradient patterns (SBGP). To discover underlying local structures in…

Computer Vision and Pattern Recognition · Computer Science 2015-06-02 Weilin Huang , Hujun Yin

Accurate molecular geometries are a prerequisite for reliable quantum-chemical predictions, yet density functional theory (DFT) optimization remains a major bottleneck for high-throughput molecular screening. Here we present GeoOpt-Net, a…

Chemical Physics · Physics 2026-02-02 Chengchun Liu , Wendi Cai , Boxuan Zhao , Fanyang Mo

Differential Dynamic Programming (DDP) is one of the indirect methods for solving an optimal control problem. Several extensions to DDP have been proposed to add stagewise state and control constraints, which can mainly be classified as…

Optimization and Control · Mathematics 2024-09-19 Siddharth Prabhu , Srinivas Rangarajan , Mayuresh Kothare

Accurate molecular property predictions require 3D geometries, which are typically obtained using expensive methods such as density functional theory (DFT). Here, we attempt to obtain molecular geometries by relying solely on machine…

Structured pruning reduces LLM inference cost by removing low-importance architectural components. This can be viewed as learning a multiplicative gate for each component under an l0 sparsity constraint. Due to the discreteness of the l0…

Machine Learning · Computer Science 2026-05-12 Weiyu Huang , Pengle Zhang , Xiaolu Zhang , Jun Zhou , Jun Zhu , Jianfei Chen

We develop a new variational approach on level sets aiming towards convergence rate analysis of a variable Bregman proximal gradient (VBPG) method for a broad class of nonsmooth and nonconvex optimization problems. With this new approach,…

Optimization and Control · Mathematics 2019-09-05 Daoli Zhu , Sien Deng

This paper considers a class of constrained stochastic composite optimization problems whose objective function is given by the summation of a differentiable (possibly nonconvex) component, together with a certain non-differentiable (but…

Optimization and Control · Mathematics 2013-09-06 Saeed Ghadimi , Guanghui Lan , Hongchao Zhang