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The emergence of the Next Generation Sequencing increases drastically the volume of transcriptomic data. Although many standalone algorithms and workflows for novel microRNA (miRNA) prediction have been proposed, few are designed for…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-01-31 Chao-Jung Wu , Amine M. Remita , Abdoulaye Baniré Diallo

The lack of well-structured metadata annotations complicates there-usability and interpretation of the growing amount of publicly available RNA expression data. The machine learning-based prediction of metadata(data augmentation) can…

Machine Learning · Computer Science 2019-09-27 Jelena Fiosina , Maksims Fiosins , Stefan Bonn

Personal assistant systems, such as Apple Siri, Google Assistant, Amazon Alexa, and Microsoft Cortana, are becoming ever more widely used. Understanding user intent such as clarification questions, potential answers and user feedback in…

Information Retrieval · Computer Science 2020-02-06 Liu Yang , Minghui Qiu , Chen Qu , Cen Chen , Jiafeng Guo , Yongfeng Zhang , W. Bruce Croft , Haiqing Chen

Data harmonization remains a major bottleneck for integrative analysis due to heterogeneity in schemas, value representations, and domain-specific conventions. BDI-Kit provides an extensible toolkit for schema and value matching. It exposes…

Artificial Intelligence · Computer Science 2026-04-09 Roque Lopez , Yurong Liu , Christos Koutras , Juliana Freire

The exponential growth of scientific knowledge has created significant barriers to cross-disciplinary knowledge discovery, synthesis and research collaboration. In response to this challenge, we present BioSage, a novel compound AI…

Despite the widespread use of tabular data in real-world applications, most benchmarks rely on average-case metrics, which fail to reveal how model behavior varies across diverse data regimes. To address this, we propose MultiTab, a…

Machine Learning · Computer Science 2025-05-21 Kyungeun Lee , Moonjung Eo , Hye-Seung Cho , Dongmin Kim , Ye Seul Sim , Seoyoon Kim , Min-Kook Suh , Woohyung Lim

The high-throughput data generated by microarray experiments provides complete set of genes being expressed in a given cell or in an organism under particular conditions. The analysis of these enormous data has opened a new dimension for…

Computational Engineering, Finance, and Science · Computer Science 2012-11-12 Khalid Raza , Akhilesh Mishra

Compound AI Systems, integrating multiple interacting components like models, retrievers, and external tools, have emerged as essential for addressing complex AI tasks. However, current implementations suffer from inefficient resource…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-19 Gohar Irfan Chaudhry , Esha Choukse , Íñigo Goiri , Rodrigo Fonseca , Adam Belay , Ricardo Bianchini

Protein analysis tasks arising in healthcare settings often require accurate reasoning under protein sequence constraints, involving tasks such as functional interpretation of disease-related variants, protein-level analysis for clinical…

Artificial Intelligence · Computer Science 2026-03-03 Congying Liu , Taihao Li , Ming Huang , Xingyuan Wei , Peipei Liu , Yiqing Shen , Yanxu Mao , Tiehan Cui

Complex phenotypic differences among different acute leukemias cannot be fully captured by analyzing the expression levels of one single molecule, such as a miR, at a time, but requires systematic analysis of large sets of miRs. While a…

Quantitative Methods · Quantitative Biology 2015-12-23 Julián Candia , Srujana Cherukuri , Yin Guo , Kshama A. Doshi , Jayanth R. Banavar , Curt I. Civin , Wolfgang Losert

Accurate multi-turn intent classification is essential for advancing conversational AI systems. However, challenges such as the scarcity of comprehensive datasets and the complexity of contextual dependencies across dialogue turns hinder…

Computation and Language · Computer Science 2024-11-20 Junhua Liu , Yong Keat Tan , Bin Fu , Kwan Hui Lim

Healthcare professionals need effective ways to use, understand, and validate AI-driven clinical decision support systems. Existing systems face two key limitations: complex visualizations and a lack of grounding in scientific evidence. We…

Human-Computer Interaction · Computer Science 2025-07-08 Reza Samimi , Aditya Bhattacharya , Lucija Gosak , Gregor Stiglic , Katrien Verbert

MATI (Microstructural Analysis Toolbox for Imaging) is a versatile MATLAB-based toolbox that combines both simulation and data fitting capabilities for microstructural dMRI research. It provides a user-friendly, GUI-driven interface that…

Generative artificial intelligence (GenAI) has become a transformative approach in bioinformatics that often enables advancements in genomics, proteomics, transcriptomics, structural biology, and drug discovery. To systematically identify…

High quality gene models are necessary to expand the molecular and genetic tools available for a target organism, but these are available for only a handful of model organisms that have undergone extensive curation and experimental…

Background: An early diagnosis together with an accurate disease progression monitoring of multiple sclerosis is an important component of successful disease management. Prior studies have established that multiple sclerosis is correlated…

Audio and Speech Processing · Electrical Eng. & Systems 2021-09-28 Emil Svoboda , Tomáš Bořil , Jan Rusz , Tereza Tykalová , Dana Horáková , Charles R. G. Guttman , Krastan B. Blagoev , Hiroto Hatabu , Vlad I. Valtchinov

Role-Based Access Control (RBAC) struggles to adapt to dynamic enterprise environments with documents that contain information that cannot be disclosed to specific user groups. As these documents are used by LLM-driven systems (e.g., in…

Cryptography and Security · Computer Science 2025-12-24 Michele Lorenzo , Idilio Drago , Dario Salvadori , Fabio Romolo Vayr

In \textit{computer-based testing} it has become standard to collect response accuracy (RA) and response times (RTs) for each test item. IRT models are used to measure a latent variable (e.g., ability, intelligence) using the RA…

Methodology · Statistics 2021-06-21 Jean-Paul Fox , Konrad Klotzke , Ahmet Salih Simsek

Biological relation networks contain rich information for understanding the biological mechanisms behind the relationship of entities such as genes, proteins, diseases, and chemicals. The vast growth of biomedical literature poses…

Computation and Language · Computer Science 2025-01-27 Po-Ting Lai , Chih-Hsuan Wei , Shubo Tian , Robert Leaman , Zhiyong Lu

Nuclear waste management requires rigorous regulatory compliance assessment, demanding advanced decision-support systems capable of addressing complex legal, environmental, and safety considerations. This paper presents a multi-agent…

Multiagent Systems · Computer Science 2025-05-29 Dongjune Chang , Sola Kim , Young Soo Park