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Optical nanoantennas can efficiently confine light into nanoscopic hotspots, enabling single-molecule detection sensitivity at biological relevant conditions. This innovative approach to breach the diffraction limit offers a versatile…

Current optical detection schemes for single molecules require light absorption, either to produce fluorescence or direct absorption signals. This severely limits the range of molecules that can be detected, because most molecules are…

Chemical Physics · Physics 2012-07-06 Peter Zijlstra , Pedro M. R. Paulo , Michel Orrit

Metallic nanohole arrays have shown their potential as sensing tools. Important research supported by sophisticated laboratory experiments have been recently carried out, that may help to develop practical devices to be implemented in the…

Applied Physics · Physics 2019-05-01 A. Franco , D. Otaduy , A. I. Barreda , J. L. FernÁndez-Luna , S. Merino , F. GonzÁlez , F. Moreno

Nanophotonics has become a key enabling technology in biomedicine with great promises in early diagnosis and less invasive therapies. In this context, the unique capability of plasmonic noble metal nanoparticles to concentrate light on the…

Applied Physics · Physics 2017-08-02 Ozlem Yavas , Mikael Svedendahl , Paulina Dobosz , Vanesa Sanz , Romain Quidant

Monitoring plant health increasingly relies on leaf-mounted sensors that provide real-time physiological data, yet efficiently locating and sampling these sensors in complex agricultural environments remains a major challenge. We present an…

Image and Video Processing · Electrical Eng. & Systems 2025-12-12 Dexter Burns , Sanjeev Koppal

Non-trivial topology of phase is crucial for many important physics phenomena such as, for example, the Aharonov-Bohm effect 1 and the Berry phase 2. Light phase allows one to create "twisted" photons 3, 4 , vortex knots 5, dislocations 6…

Cell-based biosensors constitute a fundamental tool in biotechnology, and their relevance has greatly increased in recent years as a result of a surging demand for reduced animal testing and for high-throughput and cost-effective in vitro…

Nanofluidic systems exhibit transport characteristics that have made technological marvels such as desalination, energy harvesting, and highly sensitive biomolecule sensing possible by virtue of their ability to influence small currents due…

Fluid Dynamics · Physics 2023-08-22 John Sebastian , Yoav Green

Advanced photonic tools may enable researchers and clinicians to visualize, track, control and manipulate biological processes at the single-cell level in space and time. Biological systems are complex and highly organized on both spatial…

Optics · Physics 2021-11-30 Alina Karabchevsky , Tal Elbaz , Aviad Katiyi , Ofer Prager , Alon Friedman

Silicon nanochannel field effect transistor (FET) biosensors are one of the most promising technologies in the development of highly sensitive and label-free analyte detection for cancer diagnostics. With their exceptional electrical…

Quantitative Methods · Quantitative Biology 2014-01-07 Pritiraj Mohanty , Yu Chen , Xihua Wang , Mi K. Hong , Carol L. Rosenberg , David T. Weaver , Shyamsunder Erramilli

The aim of this research review is to propose the logic and search mechanism for the development of an artificially intelligent automaton (AIA) that can find affected cells in a 3-dimensional biological system. Research on the possible…

Computational Engineering, Finance, and Science · Computer Science 2011-07-04 Jitesh Dundas

Nonlinear optical processing of ambient natural light is highly desired in computational imaging and sensing applications. A strong optical nonlinear response that can work under weak broadband incoherent light is essential for this…

We suggest a novel concept of efficient light-trapping structures for thin-film solar cells based on arrays of planar nanoantennas operating far from plasmonic resonances. The operation principle of our structures relies on the excitation…

Mesoscale and Nanoscale Physics · Physics 2015-06-12 Constantin R. Simovski , Dmitry K. Morits , Pavel M. Voroshilov , Michael E. Guzhva , Pavel A. Belov , Yuri S. Kivshar

The selective insertion of foreign materials, such as fluorescent markers or plasmids, into living cells has been a challenging problem in cell biology.However, it is often necessary that researchers insert such materials into cells for…

Cell Behavior · Quantitative Biology 2016-02-26 Kamal Dhakal , Bryan Black , Samarendra Mohanty

We present a nanoscale color detector based on a single-walled carbon nanotube functionalized with azobenzene chromophores, where the chromophores serve as photoabsorbers and the nanotube as the electronic read-out. By synthesizing…

Materials Science · Physics 2009-03-30 Xinjian Zhou , Thomas Zifer , Bryan M. Wong , Karen L. Krafcik , Francois Leonard , Andrew L. Vance

We have investigated electromagnetically induced transparency in the spectrum of selective reflection at the interface of Rb atom vapors and a dielectric nanocell window. A nanocell with atomic vapor column thicknesses ranging from 150 to…

Atomic Physics · Physics 2024-06-25 Armen Sargsyan , Anahit Gogyan , David Sarkisyan

In biological cells and novel diagnostic devices biochemical receptors need to be sensitive to extremely small concentration changes of signaling molecules. The accuracy of such molecular signaling is ultimately limited by the counting…

Subcellular Processes · Quantitative Biology 2023-04-06 Aljaz Godec , Ralf Metzler

Heller et. Al. (Science 311, 508 (2006)) demonstrated the first DNA-CN optical sensor by wrapping a piece of double-stranded DNA around the surface of single-walled carbon nanotubes (CN). This new type of optical device can be placed inside…

Mesoscale and Nanoscale Physics · Physics 2012-09-25 Anh D. Phan , Dustin A. Tracy , N. A. Viet

The detection of biomolecules at the single molecular level have important applications in the fields of biosensing and biomedical diagnosis. Solid state nanopore (SS-nanopore) is an effective tool to perform the single molecular detection,…

Biological Physics · Physics 2022-10-14 Jing Yang , Juan Wang , Ranfeng Wu , Yiming Chen , Cheng Zhang

Aberrations limit optical systems in many situations, for example when imaging in biological tissue. Machine learning offers novel ways to improve imaging under such conditions by learning inverse models of aberrations. Learning requires…

Optics · Physics 2021-04-30 Ivan Vishniakou , Johannes D. Seelig
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