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Magnetic resonance imaging (MRI) is a cornerstone of clinical neuroimaging, yet conventional MRIs provide qualitative information heavily dependent on scanner hardware and acquisition settings. While quantitative MRI (qMRI) offers intrinsic…

Magnetic resonance imaging (MRI) offers superior soft tissue contrast and is widely used in biomedicine. However, conventional MRI is not quantitative, which presents a bottleneck in image analysis and digital healthcare. Typically,…

Quantitative MRI (qMRI) methods allow reducing the subjectivity of clinical MRI by providing numerical values on which diagnostic assessment or predictions of tissue properties can be based. However, qMRI measurements typically take more…

Medical Physics · Physics 2022-02-15 Matti Hanhela , Antti Paajanen , Mikko J. Nissi , Ville Kolehmainen

Physics-Informed Neural Networks (PINN) are emerging as a promising approach for quantitative parameter estimation of Magnetic Resonance Imaging (MRI). While existing deep learning methods can provide an accurate quantitative estimation of…

In this study, we develop a physics-informed deep learning-based method to synthesize multiple brain magnetic resonance imaging (MRI) contrasts from a single five-minute acquisition and investigate its ability to generalize to arbitrary…

Deep neural networks (DNNs) have achieved exceptional performance across various fields by learning complex, nonlinear mappings from large-scale datasets. However, they face challenges such as high memory requirements and computational…

Machine Learning · Computer Science 2025-04-21 Callen MacPhee , Yiming Zhou , Bahram Jalali

Quantitative MRI is highly desirable in terms of intrinsic tissue parameters such as T1, T2 and proton density. This approach promises to minimize diagnostic variability and differentiate normal and pathological tissues by comparing tissue…

Medical Physics · Physics 2018-06-21 Qing Lyu , Ge Wang

Magnetic Resonance Imaging (MRI) is a pivotal clinical diagnostic tool, yet its extended scanning times often compromise patient comfort and image quality, especially in volumetric, temporal and quantitative scans. This review elucidates…

Physics-driven deep learning methods have emerged as a powerful tool for computational magnetic resonance imaging (MRI) problems, pushing reconstruction performance to new limits. This article provides an overview of the recent developments…

Image and Video Processing · Electrical Eng. & Systems 2022-10-17 Kerstin Hammernik , Thomas Küstner , Burhaneddin Yaman , Zhengnan Huang , Daniel Rueckert , Florian Knoll , Mehmet Akçakaya

Deep learning (DL) models have achieved strong performance in an intelligence healthcare setting, yet most existing approaches operate as black boxes and ignore the physical processes that govern tumor growth, limiting interpretability,…

Machine Learning · Computer Science 2026-03-31 Pulock Das , Al Amin , Kamrul Hasan , Rohan Thompson , Azubike D. Okpalaeze , Liang Hong

The high computational complexity and increasing parameter counts of deep neural networks pose significant challenges for deployment in resource-constrained environments, such as edge devices or real-time systems. To address this, we…

Machine Learning · Computer Science 2025-06-17 Laura Erb , Tommaso Boccato , Alexandru Vasilache , Juergen Becker , Nicola Toschi

Large-scale wave field reconstruction requires precise solutions but faces challenges with computational efficiency and accuracy. The physics-based numerical methods like Finite Element Method (FEM) provide high accuracy but struggle with…

Machine Learning · Computer Science 2026-03-04 Huiwen Zhang , Feng Ye , Chu Ma

Purpose: The clinical feasibility and translation of many advanced quantitative MRI (qMRI) techniques are inhibited by their restriction to 'research mode', due to resource-intensive, offline parameter estimation. This work aimed to achieve…

Magnetic Resonance Imaging (MRI) is one of the most flexible and powerful medical imaging modalities. This flexibility does however come at a cost; MRI images acquired at different sites and with different parameters exhibit significant…

The task of MRI fingerprinting is to identify tissue parameters from complex-valued MRI signals. The prevalent approach is dictionary based, where a test MRI signal is compared to stored MRI signals with known tissue parameters and the most…

Computer Vision and Pattern Recognition · Computer Science 2017-07-04 Patrick Virtue , Stella X. Yu , Michael Lustig

Deep learning-based techniques have potential to optimize scan and post-processing times required for MRI-based fat quantification, but they are constrained by the lack of large training datasets. Generative models are a promising tool to…

Signal Processing · Electrical Eng. & Systems 2024-12-13 Juan P. Meneses , Yasmeen George , Christoph Hagemeyer , Zhaolin Chen , Sergio Uribe

Magnetic Resonance Fingerprinting (MRF) and other highly accelerated transient-state parameter mapping techniques enable simultaneous quantification of multiple tissue properties, but often suffer from aliasing artifacts due to compressed…

Proteins perform much of the work in living organisms, and consequently the development of efficient computational methods for protein representation is essential for advancing large-scale biological research. Most current approaches…

Quantitative Methods · Quantitative Biology 2023-06-09 Francesco Ceccarelli , Lorenzo Giusti , Sean B. Holden , Pietro Liò

Estimating $T_2$ relaxation time distributions from multi-echo $T_2$-weighted MRI ($T_2W$) data can provide valuable biomarkers for assessing inflammation, demyelination, edema, and cartilage composition in various pathologies, including…

Signal Processing · Electrical Eng. & Systems 2023-05-19 Hadas Ben-Atya , Moti Freiman

Purpose: Different Magnetic resonance imaging (MRI) modalities of the same anatomical structure are required to present different pathological information from the physical level for diagnostic needs. However, it is often difficult to…

Image and Video Processing · Electrical Eng. & Systems 2021-09-15 Yuchen Fei , Bo Zhan , Mei Hong , Xi Wu , Jiliu Zhou , Yan Wang
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