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The analysis of Magnetic Resonance Imaging (MRI) sequences enables clinical professionals to monitor the progression of a brain tumor. As the interest for automatizing brain volume MRI analysis increases, it becomes convenient to have each…

Image and Video Processing · Electrical Eng. & Systems 2021-06-08 Jean Pablo Vieira de Mello , Thiago M. Paixão , Rodrigo Berriel , Mauricio Reyes , Claudine Badue , Alberto F. De Souza , Thiago Oliveira-Santos

Biophysical model fitting plays a key role in obtaining quantitative parameters from physiological signals and images. However, the model complexity for molecular magnetic resonance imaging (MRI) often translates into excessive computation…

Medical Physics · Physics 2025-04-18 Alex Finkelstein , Nikita Vladimirov , Moritz Zaiss , Or Perlman

This paper discusses an approach for incorporating prior physical knowledge into the neural network to improve data efficiency and the generalization of predictive models. If the dynamics of a system approximately follows a given…

Neural and Evolutionary Computing · Computer Science 2020-05-29 Andrei Ivanov , Uwe Iben , Anna Golovkina

Purpose: To develop neural network (NN)-based quantitative MRI parameter estimators with minimal bias and a variance close to the Cram\'er-Rao bound. Theory and Methods: We generalize the mean squared error loss to control the bias and…

Medical Physics · Physics 2024-05-07 Andrew Mao , Sebastian Flassbeck , Jakob Assländer

Mapping computed tomography (CT) number to material property dominates the proton range uncertainty. This work aims to develop a physics-constrained deep learning-based multimodal imaging (PDMI) framework to integrate physics, deep…

Quantum state tomography (QST) faces exponential measurement requirements and noise sensitivity in multi-qubit systems, bottlenecking practical quantum technologies. We present a physics-informed neural network (PINN) framework integrating…

Quantum Physics · Physics 2025-12-17 Changchun Feng , Laifa Tao , Lin Chen

Deep neural networks have excelled on a wide range of problems, from vision to language and game playing. Neural networks very gradually incorporate information into weights as they process data, requiring very low learning rates. If the…

We introduce a novel methodology that leverages the strength of Physics-Informed Neural Networks (PINNs) to address the counterdiabatic (CD) protocol in the optimization of quantum circuits comprised of systems with $N_{Q}$ qubits. The…

BACKGROUND AND PURPOSE: Deep learning has been demonstrated effective in many neuroimaging applications. However, in many scenarios, the number of imaging sequences capturing information related to small vessel disease lesions is…

In the fields of brain-computer interaction and cognitive neuroscience, effective decoding of auditory signals from task-based functional magnetic resonance imaging (fMRI) is key to understanding how the brain processes complex auditory…

Neurons and Cognition · Quantitative Biology 2024-06-05 Wanli Ma , Xuegang Tang , Jin Gu , Ying Wang , Yuling Xia

With the wide adoption of functional magnetic resonance imaging (fMRI) by cognitive neuroscience researchers, large volumes of brain imaging data have been accumulated in recent years. Aggregating these data to derive scientific insights…

Applications · Statistics 2020-06-01 Ming Bo Cai , Michael Shvartsman , Anqi Wu , Hejia Zhang , Xia Zhu

In MR fingerprinting (MRF) reconstruction, measured data is pattern-matched to simulated signals to extract quantitative tissue parameters. A critical drawback to this approach is the exponentially increasing compute time for mapping of…

Medical Physics · Physics 2024-07-17 Victoria Y. Yu , Kathryn R. Tringale , Ricardo Otazo , Ouri Cohen

Data-driven methods have become increasingly more prominent for musculoskeletal modelling due to their conceptually intuitive simple and fast implementation. However, the performance of a pre-trained data-driven model using the data from…

Signal Processing · Electrical Eng. & Systems 2022-11-23 Jie Zhang , Yihui Zhao , Tianzhe Bao , Zhenhong Li , Kun Qian , Alejandro F. Frangi , Sheng Quan Xie , Zhi-Qiang Zhang

Following the success of deep learning in a wide range of applications, neural network-based machine learning techniques have received interest as a means of accelerating magnetic resonance imaging (MRI). A number of ideas inspired by deep…

Signal Processing · Electrical Eng. & Systems 2019-04-03 Florian Knoll , Kerstin Hammernik , Chi Zhang , Steen Moeller , Thomas Pock , Daniel K. Sodickson , Mehmet Akcakaya

Quantitative susceptibility mapping (QSM) utilizes MRI signal phase to infer estimates of local tissue magnetism (magnetic susceptibility), which has been shown useful to provide novel image contrast and as biomarkers of abnormal tissue.…

Medical Physics · Physics 2019-04-16 Juan Liu , Kevin M. Koch

This work presents a multi-resolution physics-informed recurrent neural network (MR PI-RNN), for simultaneous prediction of musculoskeletal (MSK) motion and parameter identification of the MSK systems. The MSK application was selected as…

Machine Learning · Computer Science 2023-05-29 Karan Taneja , Xiaolong He , Qizhi He , J. S. Chen

Purpose: To develop a self-supervised scan-specific deep learning framework for reconstructing accelerated multiparametric quantitative MRI (qMRI). Methods: We propose REFINE-MORE (REference-Free Implicit NEural representation with MOdel…

Medical Physics · Physics 2025-08-05 Ruimin Feng , Albert Jang , Xingxin He , Fang Liu

In this paper, we develop a deep learning approach for the accurate solution of challenging problems of near-field microscopy that leverages the powerful framework of physics-informed neural networks (PINNs) for the inversion of the complex…

Optics · Physics 2024-06-12 Yuyao Chen , Luca Dal Negro

Longitudinal MRIs are often used to capture the gradual deterioration of brain structure and function caused by aging or neurological diseases. Analyzing this data via machine learning generally requires a large number of ground-truth…

Computer Vision and Pattern Recognition · Computer Science 2021-06-21 Jiahong Ouyang , Qingyu Zhao , Ehsan Adeli , Edith V Sullivan , Adolf Pfefferbaum , Greg Zaharchuk , Kilian M Pohl

Research studies have shown no qualms about using data driven deep learning models for downstream tasks in medical image analysis, e.g., anatomy segmentation and lesion detection, disease diagnosis and prognosis, and treatment planning.…

Image and Video Processing · Electrical Eng. & Systems 2022-04-06 Jiahao Huang , Yingying Fang , Yang Nan , Huanjun Wu , Yinzhe Wu , Zhifan Gao , Yang Li , Zidong Wang , Pietro Lio , Daniel Rueckert , Yonina C. Eldar , Guang Yang