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The government's effort to alleviate HIV stigma has been justified by the suppression effect of stigma on the HIV testing rate. Nevertheless, the deterrence effect of stigma on undesirable sexual behaviours has long been overlooked. This…

General Economics · Economics 2025-12-01 Pengyu Li

The control of opportunistic infections among HIV infected individuals should be one of the major public health concerns in reducing mortality rate of individuals living with HIV/AIDS. In this study a deterministic co-infection mathematical…

Dynamical Systems · Mathematics 2024-08-02 Michael Byamukama , Damian Kajunguri , Martin Karuhanga

Youth experiencing homelessness (YEH) are subject to substantially greater risk of HIV infection, compounded both by their lack of access to stable housing and the disproportionate representation of youth of marginalized racial, ethnic, and…

Social and Information Networks · Computer Science 2020-12-04 Bryan Wilder , Laura Onasch-Vera , Graham Diguiseppi , Robin Petering , Chyna Hill , Amulya Yadav , Eric Rice , Milind Tambe

When modelling HIV epidemics, it is important to incorporate set-point viral load and its heritability. As set-point viral load distributions can differ significantly amongst epidemics, it is imperative to account for the observed local…

Populations and Evolution · Quantitative Biology 2018-11-28 Pieter Libin , Laurens Hernalsteen , Kristof Theys , Perpetua Gomes , Ana Abecasis , Ann Nowe

A growing area of research in epidemiology is the identification of health-related sibling spillover effects, or the effect of one individual's exposure on their sibling's outcome. The health and health care of family members may be…

Methodology · Statistics 2021-05-06 David C. Mallinson , Felix Elwert

We propose a population model for HIV-TB co-infection dynamics by considering treatments for HIV infection, active tuberculosis and co-infection. The HIV only and TB only models are analyzed separately, as well as full model. The basic…

Populations and Evolution · Quantitative Biology 2018-08-10 Sachin Kumar , Shikha Jain

Social context plays an important role in perpetuating or reducing HIV risk behaviors. This study analyzed the network and individual attributes that were associated with the likelihood that people who inject drugs (PWID) will engage in HIV…

Computers and Society · Computer Science 2021-08-30 Valerie Ryan , TingFang Lee , Ashley L. Buchanan , Natallia V. Katenka , Samuel R. Friedman , Georgios Nikolopoulos

Statistical inference of heterogeneous treatment effects (HTEs) across predefined subgroups is challenging when units interact because treatment effects may vary by pre-treatment variables, post-treatment exposure variables (that measure…

Econometrics · Economics 2024-10-02 Julius Owusu

In causal inference, measuring treatment heterogeneity is crucial as it provides scientific insights into how treatments influence outcomes and guides personalized decision-making. In this work, we study semi-supervised settings where a…

Methodology · Statistics 2025-09-08 Yilizhati Anniwaer , Yuqian Zhang

Representative risk estimation is fundamental to clinical decision-making. However, risks are often estimated from non-representative epidemiologic studies, which usually underrepresent minorities. "Model-based" methods use population…

Methodology · Statistics 2023-04-12 Lingxiao Wang , Yan Li , Barry I. Graubard , Hormuzd A. Katki

This paper develops a continuous functional framework for treatment effects propagating through geographic space and economic networks. We derive a master equation from three independent economic foundations -- heterogeneous agent…

Econometrics · Economics 2025-12-29 Tatsuru Kikuchi

In recent years, mathematical models have become an indispensable tool in the planning, evaluation, and implementation of public health interventions. Models must often provide detailed information for many levels of population…

Dynamical Systems · Mathematics 2024-06-05 Alex Viguerie , Chiara Piazzola , Md Hafizul Islam , Evin Uzun Jacobson

During an infection, HIV experiences strong selection by immune system T cells. Recent experimental work has shown that MHC escape mutations form an important pathway for HIV to avoid such selection. In this paper, we study a model of MHC…

Probability · Mathematics 2009-09-02 Sivan Leviyang

Unveiling individuals' preferences for connecting with similar others (choice homophily) beyond the structural factors determining the pool of opportunities, is a challenging task. Here, we introduce a robust methodology for quantifying and…

Physics and Society · Physics 2024-01-25 Sina Sajjadi , Samuel Martin-Gutierrez , Fariba Karimi

This paper develops a general framework for identifying causal effects in settings with spillovers, where both outcomes and endogenous treatment decisions are influenced by peers within a known group. It introduces the generalized local…

Econometrics · Economics 2025-12-01 Huan Wu

As the global HIV pandemic enters its fourth decade, increasing numbers of surveillance sites have been established which allows countries to look into the epidemics at a finer scale, e.g. at sub-national level. However, the epidemic models…

Applications · Statistics 2014-11-18 Le Bao , Mary Mahy , Xiaoyue Niu , Tim Brown , Peter Ghys

In epidemiology, identifying subpopulations that are particularly vulnerable to exposures and those who may benefit differently from exposure-reducing interventions is essential. Factors such as age, gender-specific vulnerabilities, and…

Methodology · Statistics 2024-12-11 David McCoy , Wenxin Zhang , Alan Hubbard , Mark van der Laan , Alejandro Schuler

This paper describes a novel approach to modeling homphily, i.e. the tendency of nodes that share (or differ in) certain attributes to be linked; we consider dynamic networks in which nodes can be added over time but not removed. Our…

Genomics · Quantitative Biology 2022-01-13 V. DeGruttola , M. Nakazawa , J. Liu , X. Tu , S. Little , S. Mehta

Cluster or group randomized trials (CRTs) are increasingly used for both behavioral and system-level interventions, where entire clusters are randomly assigned to a study condition or intervention. Apart from the assigned cluster-level…

Methodology · Statistics 2024-11-19 Shubhadeep Chakraborty , Bo Wang , Ram Tiwari , Samiran Ghosh

This study utilizes mathematical models to assess progress toward achieving the UNAIDS 90-90-90 and 95-95-95 targets aimed at managing and eradicating HIV/AIDS. It contrasts stochastic and deterministic models, focusing on their utility in…

Other Quantitative Biology · Quantitative Biology 2025-03-12 Nuzhat Nuari Khan Rivu , Md Kamrujjaman , Asif Iqbal
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