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Synthetic tumors in medical images offer controllable characteristics that facilitate the training of machine learning models, leading to an improved segmentation performance. However, the existing methods of tumor synthesis yield…
Generative models are becoming popular for the synthesis of medical images. Recently, neural diffusion models have demonstrated the potential to generate photo-realistic images of objects. However, their potential to generate medical images…
Diffusion models, as powerful generative models, have found a wide range of applications and shown great potential in solving image reconstruction problems. Some works attempted to solve MRI reconstruction with diffusion models, but these…
Purpose: This study aims to develop and evaluate a three channel denoising diffusion probabilistic model (DDPM) for synthesizing single breast dual view mammograms and to assess the impact of channel representations on image fidelity and…
Diffusion models have demonstrated significant potential in producing high-quality images in medical image translation to aid disease diagnosis, localization, and treatment. Nevertheless, current diffusion models have limited success in…
Pseudo-healthy image inpainting is an essential preprocessing step for analyzing pathological brain MRI scans. Most current inpainting methods favor slice-wise 2D models for their high in-plane fidelity, but their independence across slices…
As acquiring MRIs is expensive, neuroscience studies struggle to attain a sufficient number of them for properly training deep learning models. This challenge could be reduced by MRI synthesis, for which Generative Adversarial Networks…
Accurate single cell detection in brightfield microscopy is crucial for biological research, yet data scarcity and annotation bottlenecks limit the progress of deep learning methods. We investigate the use of unconditional models to…
Scaling by training on large datasets has been shown to enhance the quality and fidelity of image generation and manipulation with diffusion models; however, such large datasets are not always accessible in medical imaging due to cost and…
Brain MRI scans are often found in four modalities, consisting of T1-weighted with and without contrast enhancement (T1ce and T1w), T2-weighted imaging (T2w), and Flair. Leveraging complementary information from these different modalities…
In recent years, Denoising Diffusion Models have demonstrated remarkable success in generating semantically valuable pixel-wise representations for image generative modeling. In this study, we propose a novel end-to-end framework, called…
Diffusion MRI is a non-invasive, in-vivo biomedical imaging method for mapping tissue microstructure. Applications include structural connectivity imaging of the human brain and detecting microstructural neural changes. However, acquiring…
Diffusion models have recently emerged as powerful generative models in medical imaging. However, it remains a major challenge to combine these data-driven models with domain knowledge to guide brain imaging problems. In neuroimaging,…
This paper presents a novel approach to simulating electronic health records (EHRs) using diffusion probabilistic models (DPMs). Specifically, we demonstrate the effectiveness of DPMs in synthesising longitudinal EHRs that capture…
Light microscopy is a widespread and inexpensive imaging technique facilitating biomedical discovery and diagnostics. However, light diffraction barrier and imperfections in optics limit the level of detail of the acquired images. The…
Magnetic resonance imaging (MRI), especially functional MRI (fMRI) and diffusion MRI (dMRI), is essential for studying neurodegenerative diseases. However, missing modalities pose a major barrier to their clinical use. Although GAN- and…
Denoising diffusion models, a class of generative models, have garnered immense interest lately in various deep-learning problems. A diffusion probabilistic model defines a forward diffusion stage where the input data is gradually perturbed…
Machine learning has significantly advanced healthcare by aiding in disease prevention and treatment identification. However, accessing patient data can be challenging due to privacy concerns and strict regulations. Generating synthetic,…
This paper presents a novel methodology for generating realistic abundance maps from hyperspectral imagery using an unsupervised, deep-learning-driven approach. Our framework integrates blind linear hyperspectral unmixing with…
The pose-guided person image generation task requires synthesizing photorealistic images of humans in arbitrary poses. The existing approaches use generative adversarial networks that do not necessarily maintain realistic textures or need…