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Unlike parametric regression, machine learning (ML) methods do not generally require precise knowledge of the true data generating mechanisms. As such, numerous authors have advocated for ML methods to estimate causal effects.…

Methodology · Statistics 2020-05-15 Ashley I Naimi , Alan E Mishler , Edward H Kennedy

Estimating long-term causal effects by combining long-term observational and short-term experimental data is a crucial but challenging problem in many real-world scenarios. In existing methods, several ideal assumptions, e.g. latent…

Machine Learning · Computer Science 2025-05-12 Ruichu Cai , Junjie Wan , Weilin Chen , Zeqin Yang , Zijian Li , Peng Zhen , Jiecheng Guo

This paper investigates causal effect identification in latent variable Linear Non-Gaussian Acyclic Models (lvLiNGAM) using higher-order cumulants, addressing two prominent setups that are challenging in the presence of latent confounding:…

Machine Learning · Statistics 2025-06-09 Daniele Tramontano , Yaroslav Kivva , Saber Salehkaleybar , Mathias Drton , Negar Kiyavash

Causal discovery aims to estimate causal structures among variables based on observational data. Large Language Models (LLMs) offer a fresh perspective to tackle the causal discovery problem by reasoning on the metadata associated with…

Computation and Language · Computer Science 2024-07-31 Yuni Susanti , Michael Färber

Large language models (LLMs) have achieved remarkable performance on diverse benchmarks, yet existing evaluation practices largely rely on coarse summary metrics that obscure underlying reasoning abilities. In this work, we propose novel…

Methodology · Statistics 2026-03-17 Jia Liu , Zhiyu Xu , Yuqi Gu

Numerous decision-making tasks require estimating causal effects under interventions on different parts of a system. As practitioners consider using large language models (LLMs) to automate decisions, studying their causal reasoning…

Machine Learning · Computer Science 2024-12-24 Tejas Kasetty , Divyat Mahajan , Gintare Karolina Dziugaite , Alexandre Drouin , Dhanya Sridhar

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

Large language models (LLMs) have recently demonstrated impressive capabilities across a range of reasoning and generation tasks. However, research studies have shown that LLMs lack the ability to identify causal relationships, a…

Machine Learning · Computer Science 2025-11-21 Juncheng Dong , Yiling Liu , Ahmed Aloui , Vahid Tarokh , David Carlson

Recent advances in the intrinsic reasoning capabilities of large language models (LLMs) have given rise to LLM-based agent systems that exhibit near-human performance on a variety of automated tasks. However, although these systems share…

Artificial Intelligence · Computer Science 2025-08-26 Bingxi Zhao , Lin Geng Foo , Ping Hu , Christian Theobalt , Hossein Rahmani , Jun Liu

The ability to robustly identify causal relationships is essential for autonomous decision-making and adaptation to novel scenarios. However, accurately inferring causal structure requires integrating both world knowledge and abstract…

Machine Learning · Computer Science 2025-06-17 Khurram Yamin , Shantanu Gupta , Gaurav R. Ghosal , Zachary C. Lipton , Bryan Wilder

Clinical diagnosis is a complex reasoning process in which clinicians gather evidence, form hypotheses, and test them against alternative explanations. In medical training, this reasoning is explicitly developed through counterfactual…

Computation and Language · Computer Science 2026-04-24 Zhiwen You , Xi Chen , Aniket Vashishtha , Simo Du , Gabriel Erion-Barner , Hongyuan Mei , Hao Peng , Yue Guo

Large Language Models (LLMs), originally developed for natural language processing (NLP), have demonstrated the potential to generalize across modalities and domains. With their in-context learning (ICL) capabilities, LLMs can perform…

Artificial Intelligence · Computer Science 2025-08-26 Nikolaos Pavlidis , Vasilis Perifanis , Symeon Symeonidis , Pavlos S. Efraimidis

Power system time series analytics is critical in understanding the system operation conditions and predicting the future trends. Despite the wide adoption of Artificial Intelligence (AI) tools, many AI-based time series analytical models…

Signal Processing · Electrical Eng. & Systems 2025-11-12 Zhenghao Zhou , Yiyan Li , Xinjie Yu , Runlong Liu , Zelin Guo , Zheng Yan , Mo-Yuen Chow , Yuqi Yang , Yang Xu

Corpus linguistics has traditionally relied on human researchers to formulate hypotheses, construct queries, and interpret results - a process demanding specialized technical skills and considerable time. We propose Agent-Driven Corpus…

Computation and Language · Computer Science 2026-04-09 Jia Yu , Weiwei Yu , Pengfei Xiao , Fukun Xing

Agent-based social simulation provides a valuable methodology for predicting social information diffusion, yet existing approaches face two primary limitations. Traditional agent models often rely on rigid behavioral rules and lack semantic…

Computers and Society · Computer Science 2025-10-21 Xinyi Li , Zhiqiang Guo , Qinglang Guo , Hao Jin , Weizhi Ma , Min Zhang

Large Language Model (LLM)-based agents have demonstrated strong capabilities across a wide range of tasks, and their application in the medical domain holds particular promise due to the demand for high generalizability and reliance on…

Artificial Intelligence · Computer Science 2025-08-18 Yangyang Zhuang , Wenjia Jiang , Jiayu Zhang , Ze Yang , Joey Tianyi Zhou , Chi Zhang

Objective: To demonstrate the capabilities of Large Language Models (LLMs) as autonomous agents to reproduce findings of published research studies using the same or similar dataset. Materials and Methods: We used the "Quick Access" dataset…

Computation and Language · Computer Science 2025-06-02 Nic Dobbins , Christelle Xiong , Kristine Lan , Meliha Yetisgen

Contextual causal reasoning is a critical yet challenging capability for Large Language Models (LLMs). Existing benchmarks, however, often evaluate this skill in fragmented settings, failing to ensure context consistency or cover the full…

Computation and Language · Computer Science 2026-04-17 Pengfeng Li , Chen Huang , Chaoqun Hao , Hongyao Chen , Xiao-Yong Wei , Wenqiang Lei , See-Kiong Ng

We assess the ability of large language models (LLMs) to answer causal questions by analyzing their strengths and weaknesses against three types of causal question. We believe that current LLMs can answer causal questions with existing…

The causal relationships between biomarkers are essential for disease diagnosis and medical treatment planning. One notable application is Alzheimer's disease (AD) diagnosis, where certain biomarkers may influence the presence of others,…

Information Retrieval · Computer Science 2025-06-13 Xiaofan Zhou , Liangjie Huang , Pinyang Cheng , Wenpen Yin , Rui Zhang , Wenrui Hao , Lu Cheng
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