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Researchers across the globe are seeking to rapidly repurpose existing drugs or discover new drugs to counter the the novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). One promising…

A novel behavior-epidemiology model, which considers $n$ heterogeneous behavioral groups based on level of risk tolerance and distinguishes behavioral changes by social and disease-related motivations (such as peer-influence and fear of…

Dynamical Systems · Mathematics 2025-01-14 Alice Oveson , Michelle Girvan , Abba Gumel

The rapid spread of SARS-CoV-2 caused the COVID-19 pandemic and accelerated vaccine development to prevent the spread of the virus and control the disease. Given the sustained high infectivity and evolution of SARS-CoV-2, there is an…

In this paper, we explore whether the infection-rate of a disease can serve as a robust monitoring variable in epidemiological surveillance algorithms. The infection-rate is dependent on population mixing patterns that do not vary…

Applications · Statistics 2024-07-17 Wyatt Bridgman , Cosmin Safta , Jaideep Ray

The long-term effects of Postacute Sequelae of SARS-CoV-2, known as PASC, pose a significant challenge to healthcare systems worldwide. Accurate identification of progression events, such as hospitalization and reinfection, is essential for…

Machine Learning · Computer Science 2025-07-01 Jing Wang , Amar Sra , Jeremy C. Weiss

Effective visualizations were evaluated to reveal relevant health patterns from multi-sensor real-time wearable devices that recorded vital signs from patients admitted to hospital with COVID-19. Furthermore, specific challenges associated…

Human-Computer Interaction · Computer Science 2022-01-20 Susanne K. Suter , Georg R. Spinner , Bianca Hoelz , Sofia Rey , Sujeanthraa Thanabalasingam , Jens Eckstein , Sven Hirsch

At the end of April 20, 2020, there were only a few new COVID-19 cases remaining in China, whereas the rest of the world had shown increases in the number of new cases. It is of extreme importance to develop an efficient statistical model…

Methodology · Statistics 2021-03-01 Xiaoping Shi , Meiqian Chen , Yucheng Dong

Although previous infection and vaccination provide protection against SARS-CoV-2 infection, both reinfection and breakthrough infection are possible events whose occurrence would increase with time after first exposure to the antigen and…

Populations and Evolution · Quantitative Biology 2022-06-07 Ariel Félix Gualtieri , Carolina de la Cal , Augusto Francisco Toma , Pedro Hecht

High throughput sequencing is a technology that allows for the generation of millions of reads of genomic data regarding a study of interest, and data from high throughput sequencing platforms are usually count compositions. Subsequent…

Quantitative Methods · Quantitative Biology 2017-04-07 Jia R. Wu , Jean M. Macklaim , Briana L. Genge , Gregory B. Gloor

We demonstrate the ability of statistical data assimilation to identify the measurements required for accurate state and parameter estimation in an epidemiological model for the novel coronavirus disease COVID-19. Our context is an effort…

Populations and Evolution · Quantitative Biology 2020-08-04 Eve Armstrong , Manuela Runge , Jaline Gerardin

Several important aspects related to SARS-CoV-2 transmission are not well known due to a lack of appropriate data. However, mathematical and computational tools can be used to extract part of this information from the available data, like…

Populations and Evolution · Quantitative Biology 2022-04-01 Nicolas Franco , Pietro Coletti , Lander Willem , Leonardo Angeli , Adrien Lajot , Steven Abrams , Philippe Beutels , Christel Faes , Niel Hens

In this work, we derive a system of Boltzmann-type equations to describe the spread of SARS-CoV-2 virus at the microscopic scale, that is by modeling the human-to-human mechanisms of transmission. To this end, we consider two populations,…

Populations and Evolution · Quantitative Biology 2024-02-09 Marzia Bisi , Silvia Lorenzani

The accuracy and robustness of numerical models of geologic CO$_2$ sequestration are almost never quantified with respect to direct observations that provide a ground truth. Here, we conduct CO$_2$ injection experiments in meter-scale,…

Timely and rapid diagnoses are core to informing on optimum interventions that curb the spread of COVID-19. The use of medical images such as chest X-rays and CTs has been advocated to supplement the Reverse-Transcription Polymerase Chain…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Ogechukwu Ukwandu , Hanan Hindy , Elochukwu Ukwandu

Repeated asymptomatic screening for SARS-CoV-2 promises to control spread of the virus but would require too many resources to implement at scale. Group testing is promising for screening more people with fewer test resources: multiple…

Populations and Evolution · Quantitative Biology 2020-11-18 Yifan Lin , Yuxuan Ren , Jingyuan Wan , Massey Cashore , Jiayue Wan , Yujia Zhang , Peter Frazier , Enlu Zhou

Climate change poses increasingly complex challenges to our society. Extreme weather events such as floods, wild fires or droughts are becoming more frequent, spontaneous and difficult to foresee or counteract. In this work we specifically…

Machine Learning · Computer Science 2024-01-08 Teodor Chiaburu , Felix Biessmann

Climate change poses complex challenges, with extreme weather events becoming increasingly frequent and difficult to model. Examples include the dynamics of Combined Sewer Systems (CSS). Overburdened CSS during heavy rainfall will overflow…

Systems and Control · Electrical Eng. & Systems 2025-02-14 Vipin Singh , Tianheng Ling , Teodor Chiaburu , Felix Biessmann

In December 2019, a newly discovered SARS-CoV-2 virus was emerged from China and propagated worldwide as a pandemic. In the absence of preventive medicine or a ready to use vaccine, mathematical models can provide useful scientific insights…

Populations and Evolution · Quantitative Biology 2020-06-30 Indrajit Ghosh

In the context of continued spread of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 and the emergence of new variants, the demand for rapid, accurate, and frequent detection is increasing. Besides, the new predominant strain,…

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