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To help the open-source community have a better understanding of Mixture-of-Experts (MoE) based large language models (LLMs), we train and release OpenMoE, a series of fully open-sourced and reproducible decoder-only MoE LLMs, ranging from…

Computation and Language · Computer Science 2024-03-28 Fuzhao Xue , Zian Zheng , Yao Fu , Jinjie Ni , Zangwei Zheng , Wangchunshu Zhou , Yang You

The proliferation of large language models (LLMs) has driven the adoption of Mixture-of-Experts (MoE) architectures as a promising solution to scale model capacity while controlling computational costs. However, deploying MoE models in…

Networking and Internet Architecture · Computer Science 2025-08-14 Muqing Li , Ning Li , Xin Yuan , Wenchao Xu , Quan Chen , Song Guo , Haijun Zhang

Large language models (LLMs) are having transformative impacts across a wide range of scientific fields, particularly in the biomedical sciences. Just as the goal of Natural Language Processing is to understand sequences of words, a major…

Genomics · Quantitative Biology 2024-09-24 Gonzalo Benegas , Chengzhong Ye , Carlos Albors , Jianan Canal Li , Yun S. Song

Mixture of experts (MoE) architectures have become a cornerstone for scaling up and are a key component in most large language models such as GPT-OSS, DeepSeek-V3, Llama-4, and Gemini-2.5. However, systematic research on MoE remains…

Computation and Language · Computer Science 2026-02-11 Nam V. Nguyen , Thong T. Doan , Luong Tran , Van Nguyen , Quang Pham

Mixture-of-Experts (MoE) has gained increasing popularity as a promising framework for scaling up large language models (LLMs). However, training MoE from scratch in a large-scale setting still suffers from data-hungry and instability…

Computation and Language · Computer Science 2024-06-25 Tong Zhu , Xiaoye Qu , Daize Dong , Jiacheng Ruan , Jingqi Tong , Conghui He , Yu Cheng

Native multimodal large language models (MLLMs) restructure a single large language model (LLM) into a spoken language model (SLM) capable of both speech and text generation. Compared to modular and aligned MLLMs, native MLLMs preserve…

Computation and Language · Computer Science 2025-10-28 Hang Shao , Heting Gao , Yunhang Shen , Jiawei Chen , Zuwei Long , Dong Yang , Ke Li , Xing Sun

Mixture of Experts (MoE) models have enabled the scaling of Large Language Models (LLMs) and Vision Language Models (VLMs) by achieving massive parameter counts while maintaining computational efficiency. However, MoEs introduce several…

Recent advancements in Large Multimodal Models (LMMs) have attracted interest in their generalization capability with only a few samples in the prompt. This progress is particularly relevant to the medical domain, where the quality and…

Computation and Language · Computer Science 2024-05-06 Seonhee Cho , Choonghan Kim , Jiho Lee , Chetan Chilkunda , Sujin Choi , Joo Heung Yoon

Mixture of Experts (MoE) models have emerged as a promising paradigm for scaling language models efficiently by activating only a subset of parameters for each input token. In this report, we present dots.llm1, a large-scale MoE model that…

Recently, Multimodal Large Language Models (MLLMs) have demonstrated impressive performance on instruction-following tasks by integrating pretrained visual encoders with large language models (LLMs). However, existing approaches often…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Wayner Barrios , Andrés Villa , Juan León Alcázar , SouYoung Jin , Bernard Ghanem

Combining existing pre-trained expert LLMs is a promising avenue for scalably tackling large-scale and diverse tasks. However, selecting task-level experts is often too coarse-grained, as heterogeneous tasks may require different expertise…

Computation and Language · Computer Science 2025-07-22 Justin Chih-Yao Chen , Sukwon Yun , Elias Stengel-Eskin , Tianlong Chen , Mohit Bansal

Parameter-efficient fine-tuning techniques like Low-Rank Adaptation (LoRA) have revolutionized the adaptation of large language models (LLMs) to diverse tasks. Recent efforts have explored mixtures of LoRA modules for multi-task settings.…

Computation and Language · Computer Science 2024-08-06 Lin Ning , Harsh Lara , Meiqi Guo , Abhinav Rastogi

Mixture-of-Experts (MoE) Multimodal large language models (MLLMs) excel at vision-language tasks, but they suffer from high computational inefficiency. To reduce inference overhead, expert skipping methods have been proposed to deactivate…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Yushi Huang , Zining Wang , Zhihang Yuan , Yifu Ding , Ruihao Gong , Jinyang Guo , Xianglong Liu , Jun Zhang

DNA methylation (DNAme) is a critical component of the epigenetic regulatory machinery and aberrations in DNAme patterns occur in many diseases, such as cancer. Mapping and understanding DNAme profiles offers considerable promise for…

Large Language Models (LLMs) typically generate outputs token by token using a fixed compute budget, leading to inefficient resource utilization. To address this shortcoming, recent advancements in mixture of expert (MoE) models,…

Large language models allocate uniform computation across all tokens, ignoring that some sequences are trivially predictable while others require deep reasoning. We introduce ConceptMoE, which dynamically merges semantically similar tokens…

Machine Learning · Computer Science 2026-01-30 Zihao Huang , Jundong Zhou , Xingwei Qu , Qiyang Min , Ge Zhang

Large Language models (LLMs) have emerged as powerful tools for addressing challenges across diverse domains. Notably, recent studies have demonstrated that large language models significantly enhance the efficiency of biomolecular analysis…

Computation and Language · Computer Science 2025-03-07 Jiyue Jiang , Zikang Wang , Yuheng Shan , Heyan Chai , Jiayi Li , Zixian Ma , Xinrui Zhang , Yu Li

Multimodal large language models (MLLMs) have demonstrated impressive capabilities across various vision-language tasks. However, a generalist MLLM typically underperforms compared with a specialist MLLM on most VL tasks, which can be…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Leyang Shen , Gongwei Chen , Rui Shao , Weili Guan , Liqiang Nie

Optimizing various wireless user tasks poses a significant challenge for networking systems because of the expanding range of user requirements. Despite advancements in Deep Reinforcement Learning (DRL), the need for customized optimization…

Networking and Internet Architecture · Computer Science 2024-02-16 Hongyang Du , Guangyuan Liu , Yijing Lin , Dusit Niyato , Jiawen Kang , Zehui Xiong , Dong In Kim

Recent advancements have shown that the Mixture of Experts (MoE) approach significantly enhances the capacity of large language models (LLMs) and improves performance on downstream tasks. Building on these promising results, multi-modal…

Computation and Language · Computer Science 2025-06-02 Linglin Jing , Yuting Gao , Zhigang Wang , Wang Lan , Yiwen Tang , Wenhai Wang , Kaipeng Zhang , Qingpei Guo