Related papers: Benchmarking Foundation Models for Mitotic Figure …
Mitotic figures are classified into typical and atypical variants, with atypical counts correlating strongly with tumor aggressiveness. Accurate differentiation is therefore essential for patient prognostication and resource allocation, yet…
Foundation models pretrained on large-scale pathology datasets have shown promising results across various diagnostic tasks. Here, we present a systematic evaluation of transfer learning strategies for brain tumor classification using these…
Manual count of mitotic figures, which is determined in the tumor region with the highest mitotic activity, is a key parameter of most tumor grading schemes. It can be, however, strongly dependent on the area selection due to uneven mitotic…
Background and objective: Employing deep learning models in critical domains such as medical imaging poses challenges associated with the limited availability of training data. We present a strategy for improving the performance and…
Low-rank adaptation of large models, particularly LoRA, has gained traction due to its computational efficiency. This efficiency, contrasted with the prohibitive costs of full-model fine-tuning, means that practitioners often turn to LoRA…
Low-rank adaptations (LoRAs) have revolutionized the finetuning of large foundation models, enabling efficient adaptation even with limited computational resources. The resulting proliferation of LoRAs presents exciting opportunities for…
Identification and counting of cells and mitotic figures is a standard task in diagnostic histopathology. Due to the large overall cell count on histological slides and the potential sparse prevalence of some relevant cell types or mitotic…
There has been a significant increase in the deployment of neural network models, presenting substantial challenges in model adaptation and fine-tuning. Efficient adaptation is crucial in maintaining model performance across diverse tasks…
Despite recent advancements in the field of medical image analysis with the use of pretrained foundation models, the issue of distribution shifts between cross-source images largely remains adamant. To circumvent that issue, investigators…
The detection of mitotic figures from different scanners/sites remains an important topic of research, owing to its potential in assisting clinicians with tumour grading. The MItosis DOmain Generalization (MIDOG) challenge aims to test the…
Large-scale multimodal foundation models, particularly Contrastive Captioners (CoCa), have achieved state-of-the-art results by unifying contrastive alignment with generative captioning. While zero-shot transfer capabilities are…
Large Language Models (LLMs) such as ChatGPT demonstrate strong few-shot adaptability without requiring fine-tuning, positioning them ideal for data-limited and real-time applications. However, this adaptability has not yet been replicated…
Mitotic activity is key for the assessment of malignancy in many tumors. Moreover, it has been demonstrated that the proportion of abnormal mitosis to normal mitosis is of prognostic significance. Atypical mitotic figures (MF) can be…
Pre-training Large Language Models (LLMs) on web-scale datasets becomes fundamental for advancing general-purpose AI. In contrast, enhancing their predictive performance on downstream tasks typically involves adapting their knowledge…
Parameter-efficient fine-tuning (PEFT) has been widely employed for domain adaptation, with LoRA being one of the most prominent methods due to its simplicity and effectiveness. However, in multi-task learning (MTL) scenarios, LoRA tends to…
Foundation models open up new possibilities for the use of AI in healthcare. However, even when pre-trained on health data, they still need to be fine-tuned for specific downstream tasks. Furthermore, although foundation models reduce the…
Foundation models, i.e., very large deep learning models, have demonstrated impressive performances in various language and vision tasks that are otherwise difficult to reach using smaller-size models. The major success of GPT-type of…
Recognizing atypical mitotic figures in histopathology images allows physicians to correctly assess tumor aggressiveness. Although machine learning models could be exploited for automatically performing such a task, under domain shift these…
It is a common practice in natural language processing to pre-train a single model on a general domain and then fine-tune it for downstream tasks. However, when it comes to Large Language Models, fine-tuning the entire model can be…
Since the emergence of the ImageNet dataset, the pretraining and fine-tuning approach has become widely adopted in computer vision due to the ability of ImageNet-pretrained models to learn a wide variety of visual features. However, a…