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The aim of the systematic review was to assess recently published studies on diagnostic test accuracy of glioblastoma treatment response monitoring biomarkers in adults, developed through machine learning (ML). Articles were searched for…

Automated grading of diabetic retinopathy (DR) faces several critical challenges: subtle inter-grade visual distinctions in fine-grained lesion patterns, distributional discrepancies induced by heterogeneous imaging devices and acquisition…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Yiqun Wang

Glioblastoma is a highly invasive brain tumor with rapid progression rates. Recent studies have shown that glioblastoma molecular subtype classification serves as a significant biomarker for effective targeted therapy selection. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Shekhnaz Idrissova , Islem Rekik

Glioblastoma recurrence is largely driven by diffuse infiltration beyond radiologically visible tumor margins, yet standard radiotherapy, the mainstay of glioblastoma treatment, relies on uniform expansions that ignore patient-specific…

Image and Video Processing · Electrical Eng. & Systems 2026-03-17 L. Zimmer , J. Weidner , M. Balcerak , F. Kofler , M. Krupa , I. Ezhov , S. Cepeda , R. Zhang , J. Lowengrub , B. Menze , B. Wiestler

Gliomas are the most common primary tumors of the central nervous system. Multimodal MRI is widely used for the preliminary screening of gliomas and plays a crucial role in auxiliary diagnosis, therapeutic efficacy, and prognostic…

Image and Video Processing · Electrical Eng. & Systems 2025-05-27 Yihao Liu , Zhihao Cui , Liming Li , Junjie You , Xinle Feng , Jianxin Wang , Xiangyu Wang , Qing Liu , Minghua Wu

Multimodal deep learning has improved prognostic accuracy for brain tumours by integrating histopathology and genomic data, yet the contribution of volumetric MRI within unified survival frameworks remains unexplored. This pilot study…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Iain Swift , JingHua Ye

Retinal diseases spanning a broad spectrum can be effectively identified and diagnosed using complementary signals from multimodal data. However, multimodal diagnosis in ophthalmic practice is typically challenged in terms of data…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Lu Zhang , Huizhen Yu , Zuowei Wang , Fu Gui , Yatu Guo , Wei Zhang , Mengyu Jia

Cancer clinics capture disease data at various scales, from genetic to organ level. Current bioinformatic methods struggle to handle the heterogeneous nature of this data, especially with missing modalities. We propose PARADIGM, a Graph…

Cell Behavior · Quantitative Biology 2024-11-22 Asim Waqas , Aakash Tripathi , Paul Stewart , Mia Naeini , Matthew B. Schabath , Ghulam Rasool

Recent advancements in Multi-modality Large Language Models (MLLMs) have demonstrated remarkable capabilities in complex high-level vision tasks. However, the exploration of MLLM potential in visual quality assessment, a vital aspect of…

Computer Vision and Pattern Recognition · Computer Science 2023-12-27 Zicheng Zhang , Haoning Wu , Zhongpeng Ji , Chunyi Li , Erli Zhang , Wei Sun , Xiaohong Liu , Xiongkuo Min , Fengyu Sun , Shangling Jui , Weisi Lin , Guangtao Zhai

One of the leading causes of blindness is glaucoma, which is challenging to detect since it remains asymptomatic until the symptoms are severe. Thus, diagnosis is usually possible until the markers are easy to identify, i.e., the damage has…

Image and Video Processing · Electrical Eng. & Systems 2021-10-05 Sayan Mandal , Alessandro A. Jammal , Felipe A. Medeiros

Dementia, a progressive neurodegenerative disorder, affects memory, reasoning, and daily functioning, creating challenges for individuals and healthcare systems. Early detection is crucial for timely interventions that may slow disease…

Neurons and Cognition · Quantitative Biology 2025-03-04 Sahar Sinene Mehdoui , Abdelhamid Bouzid , Daniel Sierra-Sosa , Adel Elmaghraby

Gradient boosting, a method of building additive ensembles from weak learners, has established itself as a practical and theoretically-motivated approach to approximate functions, especially using decision tree weak learners. Comparable…

Machine Learning · Computer Science 2026-03-26 Abhijit Chowdhary , Elizabeth Newman , Deepanshu Verma

Glioblastoma multiforme (GBM) is an aggressive form of human brain cancer that is under active study in the field of cancer biology. Its rapid progression and the relative time cost of obtaining molecular data make other readily-available…

Applications · Statistics 2019-11-14 Lorin Crawford , Anthea Monod , Andrew X. Chen , Sayan Mukherjee , Raúl Rabadán

Glioma, a prevalent and heterogeneous tumor originating from the glial cells, can be differentiated as Low Grade Glioma (LGG) and High Grade Glioma (HGG) according to World Health Organization's norms. Classifying gliomas is essential for…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Kiranmayee Janardhan , Christy Bobby Thomas

Large language models (LLMs) can simulate clinical reasoning based on natural language prompts, but their utility in ophthalmology is largely unexplored. This study evaluated GPT-4's ability to interpret structured textual descriptions of…

Computation and Language · Computer Science 2025-07-03 Cindy Lie Tabuse , David Restepo , Carolina Gracitelli , Fernando Korn Malerbi , Caio Regatieri , Luis Filipe Nakayama

Multimodal large language models (MLLMs) hold promise for integrating diverse data modalities, but current medical adaptations such as LLaVA-Med often fail to fully exploit the synergy between color fundus photography (CFP) and optical…

\textit{Objectives}: Data scarcity and domain shifts lead to biased training sets that do not accurately represent deployment conditions. A related practical problem is cross-modal image segmentation, where the objective is to segment…

Image and Video Processing · Electrical Eng. & Systems 2024-04-01 Guillaume Sallé , Pierre-Henri Conze , Julien Bert , Nicolas Boussion , Dimitris Visvikis , Vincent Jaouen

Accurate prognosis for Glioblastoma (GBM) using deep learning (DL) is hindered by extreme spatial and structural heterogeneity. Moreover, inconsistent MRI acquisition protocols across institutions hinder generalizability of models.…

Machine Learning · Computer Science 2026-02-13 Ankita Paul , Wenyi Wang

Early identification of stroke symptoms is essential for enabling timely intervention and improving patient outcomes, particularly in prehospital settings. This study presents a fast, non-invasive multimodal deep learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Ngoc-Khai Hoang , Thi-Nhu-Mai Nguyen , Huy-Hieu Pham

This study aimed to enhance disease classification accuracy from retinal fundus images by integrating fine-grained image features and global textual context using a novel multimodal deep learning architecture. Existing multimodal large…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Jason Jordan , Mohammadreza Akbari Lor , Peter Koulen , Mei-Ling Shyu , Shu-Ching Chen