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Plasticity is one of the most important properties of the nervous system, which enables animals to adjust their behavior to the ever-changing external environment. Changes in synaptic efficacy between neurons constitute one of the major…

Neurons and Cognition · Quantitative Biology 2018-01-23 Taishi Iwasaki , Hideitsu Hino , Masami Tatsuno , Shotaro Akaho , Noboru Murata

Inspired by recent successes with parallel optimization techniques for solving Boolean satisfiability, we investigate a set of strategies and heuristics that aim to leverage parallel computing to improve the scalability of neural network…

Logic in Computer Science · Computer Science 2020-08-24 Haoze Wu , Alex Ozdemir , Aleksandar Zeljić , Ahmed Irfan , Kyle Julian , Divya Gopinath , Sadjad Fouladi , Guy Katz , Corina Pasareanu , Clark Barrett

The experimental study of neural networks requires simultaneous measurements of a massive number of neurons, while monitoring properties of the connectivity, synaptic strengths and delays. Current technological barriers make such a mission…

Neurons and Cognition · Quantitative Biology 2016-01-12 Amir Goldental , Pinhas Sabo , Shira Sardi , Roni Vardi , Ido Kanter

Functional magnetic resonance imaging (fMRI) aims to locate activated regions in human brains when specific tasks are performed. The conventional tool for analyzing fMRI data applies some variant of the linear model, which is restrictive in…

Statistics Theory · Mathematics 2008-08-08 Chunming Zhang , Tao Yu

Identifying differences in networks has become a canonical problem in many biological applications. Here, we focus on testing whether two Gaussian graphical models are the same. Existing methods try to accomplish this goal by either…

Methodology · Statistics 2019-10-01 Sen Zhao , Stephen Ottinger , Suzanne Peck , Christine Mac Donald , Ali Shojaie

To learn how cognition is implemented in the brain, we must build computational models that can perform cognitive tasks, and test such models with brain and behavioral experiments. Cognitive science has developed computational models of…

Neurons and Cognition · Quantitative Biology 2018-08-01 Nikolaus Kriegeskorte , Pamela K. Douglas

We describe a project-based introduction to reproducible and collaborative neuroimaging analysis. Traditional teaching on neuroimaging usually consists of a series of lectures that emphasize the big picture rather than the foundations on…

Other Statistics · Statistics 2018-10-23 K. Jarrod Millman , Matthew Brett , Ross Barnowski , Jean-Baptiste Poline

Partial synchronization plays a crucial role in the functioning of neuronal networks: selective, coordinated activation of neurons enables information processing that flexibly adapts to a changing computational context. Since the structure…

Neurons and Cognition · Quantitative Biology 2025-06-17 Daniil Radushev , Olesia Dogonasheva , Boris Gutkin , Denis Zakharov

Recent research in neuroimaging has focused on assessing associations between genetic variants that are measured on a genomewide scale and brain imaging phenotypes. A large number of works in the area apply massively univariate analyses on…

We consider the problem of precision matrix estimation where, due to extraneous confounding of the underlying precision matrix, the data are independent but not identically distributed. While such confounding occurs in many scientific…

Machine Learning · Statistics 2019-07-01 Sinong Geng , Mladen Kolar , Oluwasanmi Koyejo

Partial conjunction (PC) hypothesis testing is widely used to assess the replicability of scientific findings across multiple comparable studies. In high-throughput meta-analyses, testing a large number of PC hypotheses with k-family-wise…

Methodology · Statistics 2025-08-22 Ninh Tran

An important field of research in functional neuroimaging is the discovery of integrated, distributed brain systems and networks, whose different regions need to work in unison for normal functioning. The EEG is a non-invasive technique…

Determining how synaptic coupling within and between regions is modulated during sensory processing is an important topic in neuroscience. Electrophysiological recordings provide detailed information about neural spiking but have…

Neurons and Cognition · Quantitative Biology 2018-02-07 Andrea K. Barreiro , Shree Hari Gautam , Woodrow L. Shew , Cheng Ly

Brain connectomics is a developing field in neurosciences which strives to understand cognitive processes and psychiatric diseases through the analysis of interactions between brain regions. However, in the high-dimensional, low-sample, and…

Applications · Statistics 2019-11-15 Claire Donnat , Leonardo Tozzi , Susan Holmes

We propose a kernel-based partial permutation test for checking the equality of functional relationship between response and covariates among different groups. The main idea, which is intuitive and easy to implement, is to keep the…

Methodology · Statistics 2021-11-01 Xinran Li , Bo Jiang , Jun S. Liu

A major challenge in neuroimaging is understanding the mapping of neurophysiological dynamics onto cognitive functions. Traditionally, these maps have been constructed by examining changes in the activity magnitude of regions related to…

The use of EEG biometrics, for the purpose of automatic people recognition, has received increasing attention in the recent years. Most of current analysis rely on the extraction of features characterizing the activity of single brain…

Neurons and Cognition · Quantitative Biology 2014-09-10 Daria La Rocca , Patrizio Campisi , Balazs Vegso , Peter Cserti , Gyorgy Kozmann , Fabio Babiloni , Fabrizio De Vico Fallani

As neuroscientific theories of consciousness continue to proliferate, the need to assess their similarities and differences - as well as their predictive and explanatory power - becomes ever more pressing. Recently, a number of structured…

Neurons and Cognition · Quantitative Biology 2026-05-18 Andrew W. Corcoran , Andrew M. Haun , Reinder Dorman , Giulio Tononi , Karl J. Friston , Cyriel M. A. Pennartz , TWCF , : , INTREPID Consortium

Inferring brain connectivity network and quantifying the significance of interactions between brain regions are of paramount importance in neuroscience. Although there have recently emerged some tests for graph inference based on…

Methodology · Statistics 2019-08-23 Yuting Ye , Yin Xia , Lexin Li

In this technical note, we address an unresolved challenge in neuroimaging statistics: how to determine which of several datasets is the best for inferring neuronal responses. Comparisons of this kind are important for experimenters when…