Related papers: $\beta$-Ga$_2$O$_3$--Based Radiation Detector for …
An ultra thin silicon detector called U3DTHIN has been designed and built for neutral particle analyzers (NPA) and thermal neutron detection. The main purpose of this detector is to provide a state-of-the-art solution for detector system of…
Background and purpose: In-beam Positron Emission Tomography (PET) is one of the modalities that can be used for in-vivo non-invasive treatment monitoring in proton therapy. PET distributions obtained during various treatment sessions can…
Purpose: To demonstrate a proton imaging system based on well-established fast scintillator technology to achieve high performance with low cost and complexity, with the potential of a straightforward translation into clinical use. Methods:…
Measurement quality assurance (QA) practices play a key role in the safe use of Intensity Modulated Radiation Therapies (IMRT) for cancer treatment. These practices have reduced measurement-based IMRT QA failure below 1%. However, these…
In the context of range monitoring for particle therapy, this study presents the first experimental results obtained with the TIARA detector using carbon-ion beams at the CNAO clinical center in Pavia, Italy. TIARA is based on the Prompt…
The Integrable Optics Test Accelerator (IOTA) at Fermilab provides a versatile platform for studying the interplay of space-charge, impedance, and non-linear optics in high-intensity hadron beams within synchrotrons and storage rings. This…
An important issue for rare-event-search experiments, such as the search for dark matter or neutrinoless double beta decay, is to reduce radioactivity of the detector materials and the experimental environment. The selection of materials…
The Medipix3, a hybrid pixel detector with a silicon sensor, has been evaluated as a beam instrumentation device with proton and carbon ion measurements in the non-clinical research room (IR1) of MedAustron Ion Therapy Center. Protons…
Laser acceleration promises innovation in particle beam therapy of cancer where an ultra-compact accelerator system for cancer beam therapy can become affordable to a broad range of patients. This is not feasible without the introduction of…
Objective. Prompt-gamma imaging encompasses several approaches for online monitoring of beam range or deposited dose distribution in proton therapy. We test one of the imaging techniques - a coded mask approach - both experimentally and via…
Ionization profile monitors (IPMs) are widely used in accelerators for non-destructive and fast diagnostics of high energy particle beams. Two such monitors - one vertical and one horizontal - are being developed for installation in the…
The primary objective of phase I oncology studies is to establish the safety profile of a new treatment and determine the maximum tolerated dose (MTD). This is motivated by the development of cytotoxic agents based on the underlying…
Targeted Radionuclide Therapy (TRT) is a well-established technique for cancer treatment. In this approach, radionuclides are bound to specific drugs that selectively transport them to the tumor site. Within the ISOLPHARM project, a…
Computer tomography is one of the most promising new methods to image abnormal tissues inside the human body. Tomography is also used to position the patient accurately before radiation therapy. Hadron therapy for treating cancer has become…
Proton irradiation of both n-type and semi-insulating bulk samples of \b{eta}-Ga2O3 leads to the formation of one paramagnetic defect with spin S=1/2, monoclinic point symmetry, a g-tensor with principal values of gb=2.0313, gc=2.0079, ga*=…
Boron Neutron Capture Therapy (BNCT) is a form of radiotherapy based on the irradiation of the tumour with a low energy neutron beam, after the administration of a selective drug enriched in boron-10. The therapy exploits the high cross…
We describe an apparatus used to measure the triple-correlation term (\D \hat{\sigma}_n\cdot p_e\times p_\nu) in the beta-decay of polarized neutrons. The \D-coefficient is sensitive to possible violations of time reversal invariance. The…
Proton beam therapy has been developed to irradiate the tumor with higher precision and dose conformity compared to conventional X-ray irradiation. The dose conformity of this treatment modality may be further improved if narrower proton…
Proton beam therapy can potentially offer improved treatment for cancers of the head and neck and in paediatric patients. There has been a sharp uptake of proton beam therapy in recent years as improved delivery techniques and patient…
The use of contrast agents has previously been proposed as a novel method to increase the activation close to the Bragg peak, aiming to improve the quality of proton range monitoring in vivo. In a recent work, we demonstrated the…