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The integration and transmission of information in the brain are dependent on the interplay between structural and dynamical properties. Implicit in any pursuit aimed at understanding neural dynamics from appropriate sets of mathematically…

Neurons and Cognition · Quantitative Biology 2020-06-30 Joshua M. Roldan , Sebastian Pardo G. , Vivek Kurien George , Gabriel A. Silva

Modern brain imaging technologies have enabled the detailed reconstruction of human brain connectomes, capturing structural connectivity (SC) from diffusion MRI and functional connectivity (FC) from functional MRI. Understanding the…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Yee-Fan Tan , Jun Lin Liow , Pei-Sze Tan , Fuad Noman , Raphael C. -W. Phan , Hernando Ombao , Chee-Ming Ting

Human brains exhibit highly organized multiscale neurophysiological dynamics. Understanding those dynamic changes and the neuronal networks involved is critical for understanding how the brain functions in health and disease. Functional…

Neurons and Cognition · Quantitative Biology 2024-09-09 Manuel Morante , Kristian Frølich , Naveed ur Rehman

The increasing quantity and quality of the publicly available human cerebral diffusion MRI data make possible the study of the brain as it was unimaginable before. The Consensus Connectome Dynamics (CCD) is a remarkable phenomenon that was…

Neurons and Cognition · Quantitative Biology 2016-10-17 Balázs Szalkai , Vince Grolmusz

This article focuses on the problem of studying shared- and individual-specific structure in replicated networks or graph-valued data. In particular, the observed data consist of $n$ graphs, $G_i, i=1,\ldots,n$, with each graph consisting…

Computation · Statistics 2018-04-13 Lu Wang , Zhengwu Zhang , David Dunson

The joint analysis of multimodal neuroimaging data is critical in the field of brain research because it reveals complex interactive relationships between neurobiological structures and functions. In this study, we focus on investigating…

Methodology · Statistics 2025-03-25 Tong Lu , Yuan Zhang , Vince Lyzinski , Chuan Bi , Peter Kochunov , Elliot Hong , Shuo Chen

The brain is immensely complex, with diverse components and dynamic interactions building upon one another to orchestrate a wide range of functions and behaviors. Understanding patterns of these complex interactions and how they are…

Neurons and Cognition · Quantitative Biology 2024-08-06 Suman Kulkarni , Dani S. Bassett

Predicting how the brain can be driven to specific states by means of internal or external control requires a fundamental understanding of the relationship between neural connectivity and activity. Network control theory is a powerful tool…

Neurons and Cognition · Quantitative Biology 2019-08-12 Teresa M. Karrer , Jason Z. Kim , Jennifer Stiso , Ari E. Kahn , Fabio Pasqualetti , Ute Habel , Danielle S. Bassett

It has become increasingly popular to study the brain as a network due to the realization that functionality cannot be explained exclusively by independent activation of specialized regions. Instead, across a large spectrum of behaviors,…

Neurons and Cognition · Quantitative Biology 2014-07-22 Petko Bogdanov , Nazli Dereli , Danielle S. Bassett , Scott T. Grafton , Ambuj K. Singh

Cognitive neuroscience explores the mechanisms of cognition by studying its structural and functional brain correlates. Here, we report the first systematic review that assesses how information from structural and functional neuroimaging…

Neurons and Cognition · Quantitative Biology 2022-02-07 Marta Czime Litwińczuk , Nelson Trujillo-Barreto , Nils Muhlert , Lauren Cloutman , Anna Woollams

We investigate the influence of indirect connections, interregional distance and collective effects on the large-scale functional networks of the human cortex. We study topologies of empirically derived resting state networks (RSNs),…

Neurons and Cognition · Quantitative Biology 2013-02-18 Vesna Vuksanović , Philipp Hövel

Connectomics and network neuroscience offer quantitative scientific frameworks for modeling and analyzing networks of structurally and functionally interacting neurons, neuronal populations, and macroscopic brain areas. This shift in…

Neurons and Cognition · Quantitative Biology 2020-10-06 Richard Betzel

The connectome, a map of the structural and/or functional connections in the brain, provides a complex representation of the neurobiological phenotypes on which it supervenes. This information-rich data modality has the potential to…

Dynamic functional connectivity (dFC) is ubiquitously observed in the brain, but why functional networks should remain dynamic even at rest is unclear. We asked whether temporal reconfiguration becomes advantageous when keeping a functional…

Biological Physics · Physics 2026-04-14 Simachew Abebe Mengiste , Demian Battaglia

The human brain is a complex network of interconnected brain regions organized into functional modules with distinct roles in cognition and behavior. An important question concerns the persistence and stability of these modules over the…

Neurons and Cognition · Quantitative Biology 2015-10-28 Richard F. Betzel , Bratislav Mišić , Ye He , Jeffrey Rumschlag , Xi-Nian Zuo , Olaf Sporns

Brain function is organized in coordinated modes of spatio-temporal activity (functional networks) exhibiting an intrinsic baseline structure with variations under different experimental conditions. Existing approaches for uncovering such…

Methodology · Statistics 2019-02-13 Joshua Lukemire , Suprateek Kundu , Giuseppe Pagnoni , Ying Guo

The correlations of several fundamental properties of human brain connections are investigated in a consensus connectome, constructed from 1064 braingraphs, each on 1015 vertices, corresponding to 1015 anatomical brain areas. The properties…

Neurons and Cognition · Quantitative Biology 2024-04-22 Dániel Hegedűs , Vince Grolmusz

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

Functional connectivity (FC) analysis of resting-state fMRI data provides a framework for characterizing brain networks and their association with participant-level covariates. Due to the high dimensionality of neuroimaging data, standard…

Methodology · Statistics 2025-08-18 Wei Zhao , Brian J. Reich , Emily C. Hector

The brain is an assembly of neuronal populations interconnected by structural pathways. Brain activity is expressed on and constrained by this substrate. Therefore, statistical dependencies between functional signals in directly connected…

Neurons and Cognition · Quantitative Biology 2019-09-11 Maria Giulia Preti , Dimitri Van De Ville