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The majority of primary Central Nervous System (CNS) tumors in the brain are among the most aggressive diseases affecting humans. Early detection of brain tumor types, whether benign or malignant, glial or non-glial, is critical for cancer…

Methodology · Statistics 2023-11-16 Liyun Zeng , Hao Helen Zhang

The magnetic resonance (MR) analysis of brain tumors is widely used for diagnosis and examination of tumor subregions. The overlapping area among the intensity distribution of healthy, enhancing, non-enhancing, and edema regions makes the…

Image and Video Processing · Electrical Eng. & Systems 2020-06-01 Mohammad Hamghalam , Baiying Lei , Tianfu Wang

Glioma is the most common form of primary brain tumor. Demographically, the risk of occurrence increases until old age. Here we present a novel computational model to reproduce the probability of glioma incidence across the lifespan.…

Cell Behavior · Quantitative Biology 2015-03-23 Roman Bauer , Marcus Kaiser , Elizabeth Stoll

Machine learning has been widely adopted for medical image analysis in recent years given its promising performance in image segmentation and classification tasks. As a data-driven science, the success of machine learning, in particular…

Computer Vision and Pattern Recognition · Computer Science 2020-07-06 Chengliang Dai , Shuo Wang , Yuanhan Mo , Kaichen Zhou , Elsa Angelini , Yike Guo , Wenjia Bai

Molecular classification has transformed the management of brain tumors by enabling more accurate prognostication and personalized treatment. However, timely molecular diagnostic testing for patients with brain tumors is limited,…

Brain tumor segmentation is a fundamental step in assessing a patient's cancer progression. However, manual segmentation demands significant expert time to identify tumors in 3D multimodal brain MRI scans accurately. This reliance on manual…

Image and Video Processing · Electrical Eng. & Systems 2024-05-07 Fadillah Maani , Anees Ur Rehman Hashmi , Numan Saeed , Mohammad Yaqub

Objective: Brain metastases (BMs) are common in cancer patients and determining the primary tumor site is crucial for effective treatment. This study aims to predict the primary tumor site from BM MRI data using radiomic features and…

Machine Learning · Computer Science 2024-07-09 Hamidreza Sadeghsalehi

Resection and whole brain radiotherapy (WBRT) are the standards of care for the treatment of patients with brain metastases (BM) but are often associated with cognitive side effects. Stereotactic radiosurgery (SRS) involves a more targeted…

Oncolytic viral therapy (OVT) is an emerging precision therapy for aggressive and recurrent cancers. However, its clinical efficacy is hindered by the complexity of tumor-virus-immune interactions and the lack of predictive models for…

Quantitative Methods · Quantitative Biology 2026-03-11 Abicumaran Uthamacumaran , Juri Kiyokawa , Hiroaki Wakimoto

Background: Differentiating radiation necrosis (RN) from tumor progression after stereotactic radiosurgery (SRS) remains a critical challenge in brain metastases. While histopathology represents the gold standard, its invasiveness limits…

Mathematical oncology provides unique and invaluable insights into tumour growth on both the microscopic and macroscopic levels. This review presents state-of-the-art modelling techniques and focuses on their role in understanding…

Brain tumor is deliberated as one of the severe health complications which lead to decrease in life expectancy of the individuals and is also considered as a prominent cause of mortality worldwide. Therefore, timely detection and prediction…

Image and Video Processing · Electrical Eng. & Systems 2023-07-18 Tejashwini P S , Thriveni J , Venugopal K R

Complete resection of malignant gliomas is hampered by the difficulty in distinguishing tumor cells at the infiltration zone. Fluorescence guidance with 5-ALA assists in reaching this goal. Using hyperspectral imaging, previous work…

Purpose: To investigate the use of a Vision Transformer (ViT) to reconstruct/denoise GABA-edited magnetic resonance spectroscopy (MRS) from a quarter of the typically acquired number of transients using spectrograms. Theory and Methods: A…

The rapidly emerging field of deep learning-based computational pathology has shown promising results in utilizing whole slide images (WSIs) to objectively prognosticate cancer patients. However, most prognostic methods are currently…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Mingxin Liu , Yunzan Liu , Hui Cui , Chunquan Li , Jiquan Ma

Gliomas are aggressive brain tumors that infiltrate surrounding tissue beyond the visible tumor margins observed on Magnetic Resonance Imaging (MRI). Predicting the spatial extent of this infiltration is essential for surgical planning and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 S M Asif Hossain , Shruti Kshirsagar

Another year of the multimodal brain tumor segmentation challenge (BraTS) 2021 provides an even larger dataset to facilitate collaboration and research of brain tumor segmentation methods, which are necessary for disease analysis and…

Image and Video Processing · Electrical Eng. & Systems 2021-11-02 Md Mahfuzur Rahman Siddiquee , Andriy Myronenko

This paper primarily addresses a dataset relating to cellular, chemical and physical conditions of patients gathered at the time they are operated upon to remove colorectal tumours. This data provides a unique insight into the biochemical…

Machine Learning · Computer Science 2016-11-17 Christopher Roadknight , Durga Suryanarayanan , Uwe Aickelin , John Scholefield , Lindy Durrant

Gastric cancer and Colon adenocarcinoma represent widespread and challenging malignancies with high mortality rates and complex treatment landscapes. In response to the critical need for accurate prognosis in cancer patients, the medical…

Image and Video Processing · Electrical Eng. & Systems 2024-04-16 Xu Yan , Weimin Wang , MingXuan Xiao , Yufeng Li , Min Gao

Identifying the extent of brain tumors is a significant challenge in brain cancer treatment. The main difficulty is in the approximate detection of tumor size. Magnetic resonance imaging (MRI) has become a critical diagnostic tool. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Rupesh Dulal , Rabin Dulal