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Sparse autoencoders (SAEs) decompose language model activations into interpretable features, but existing methods reveal only which features activate, not which change model outputs when amplified. We introduce Control Reinforcement…

Machine Learning · Computer Science 2026-05-05 Seonglae Cho , Zekun Wu , Adriano Koshiyama

Advances in healthcare research have significantly enhanced our understanding of disease mechanisms, diagnostic precision, and therapeutic options. Yet, lung cancer remains one of the leading causes of cancer-related mortality worldwide due…

Computer Vision and Pattern Recognition · Computer Science 2025-06-06 Sugandha Saxena , S. N. Prasad , Ashwin M Polnaya , Shweta Agarwala

Machine learning (ML) has revolutionized medical prognostics by integrating advanced algorithms with clinical data to enhance disease prediction, risk assessment, and patient outcome forecasting. This comprehensive review critically…

Machine Learning · Computer Science 2024-08-06 Michael Fascia

The vast amount of sequencing data presently available allow the scientific community to explore a range of genetic variables that may drive and progress cancer. A myriad of predictive tools has been proposed, allowing researchers and…

Genomics · Quantitative Biology 2023-03-31 Mona Nourbakhsh , Kristine Degn , Astrid Saksager , Matteo Tiberti , Elena Papaleo

Cylindrical manipulators are extensively used in industrial automation, especially in emerging technologies like 3D printing, which represents a significant future trend. However, controlling the trajectory of nonlinear models with system…

Systems and Control · Electrical Eng. & Systems 2025-01-10 TieuNien Le , VanCuong Pham , NgocSon Vu

Deep models, such as convolutional neural networks (CNNs) and vision transformer (ViT), demonstrate remarkable performance in image classification. However, those deep models require large data to fine-tune, which is impractical in the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Yihang Wu , Muhammad Owais , Reem Kateb , Ahmad Chaddad

Supervised machine learning classifiers sometimes face challenges related to the performance, accuracy, or overfitting. This paper introduces the Artificial Liver Classifier (ALC), a novel supervised learning model inspired by the human…

Artificial Intelligence · Computer Science 2025-09-24 Mahmood A. Jumaah , Yossra H. Ali , Tarik A. Rashid

Cancer is a highly heterogeneous condition that can occur almost anywhere in the human body. 18F-fluorodeoxyglucose is an imaging modality commonly used to detect cancer due to its high sensitivity and clear visualisation of the pattern of…

Image and Video Processing · Electrical Eng. & Systems 2023-04-17 Ashay Patel , Petru-Danial Tudiosu , Walter H. L. Pinaya , Gary Cook , Vicky Goh , Sebastien Ourselin , M. Jorge Cardoso

Machine learning (ML) tools such as encoder-decoder deep convolutional neural networks (CNN) are able to extract relationships between inputs and outputs of large complex systems directly from raw data. For time-varying systems the…

Accelerator Physics · Physics 2021-03-25 Alexander Scheinker , Frederick Cropp , Sergio Paiagua , Daniele Filippetto

Lung cancer ranks as one of the leading causes of cancer diagnosis and is the foremost cause of cancer-related mortality worldwide. The early detection of lung nodules plays a pivotal role in improving outcomes for patients, as it enables…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Jiasen Zhang , Mingrui Yang , Weihong Guo , Brian A. Xavier , Michael Bolen , Xiaojuan Li

With the development of computer technology, various models have emerged in artificial intelligence. The transformer model has been applied to the field of computer vision (CV) after its success in natural language processing (NLP).…

Computer Vision and Pattern Recognition · Computer Science 2022-07-05 Ruina Sun , Yuexin Pang

The aim of the systematic review was to assess recently published studies on diagnostic test accuracy of glioblastoma treatment response monitoring biomarkers in adults, developed through machine learning (ML). Articles were searched for…

Machine learning can precisely identify different cancer tumors at any stage by classifying cancerous and healthy samples based on their genomic profile. We have developed novel methods of MLAC (Machine Learning Against Cancer) achieving…

Genomics · Quantitative Biology 2020-09-15 Arash Hooshmand

Single-cell datasets often lack individual cell labels, making it challenging to identify cells associated with disease. To address this, we introduce Mixture Modeling for Multiple Instance Learning (MMIL), an expectation maximization…

Quantitative Methods · Quantitative Biology 2024-06-13 Erin Craig , Timothy Keyes , Jolanda Sarno , Maxim Zaslavsky , Garry Nolan , Kara Davis , Trevor Hastie , Robert Tibshirani

This paper deals with the multiple annotation problem in medical application of cancer detection in digital images. The main assumption is that though images are labeled by many experts, the number of images read by the same expert is not…

Computer Vision and Pattern Recognition · Computer Science 2014-12-10 Inna Stainvas , Alexandra Manevitch , Isaac Leichter

Malignant brain tumors have become an aggressive and dangerous disease that leads to death worldwide.Multi-modal MRI data is crucial for accurate brain tumor segmentation, but missing modalities common in clinical practice can severely…

Methodology · Statistics 2025-07-11 Guoyan Liang , Qin Zhou , Jingyuan Chen , Bingcang Huang , Kai Chen , Lin Gu , Zhe Wang , Sai Wu , Chang Yao

Modulation classification is an essential step of signal processing and has been regularly applied in the field of tele-communication. Since variations of frequency with respect to time remains a vital distinction among radio signals having…

Signal Processing · Electrical Eng. & Systems 2023-06-09 Muhammad Waqas , Muhammad Ashraf , Muhammad Zakwan

N-glycosylation is a critical quality attribute of monoclonal antibodies (mAbs), the dominant class of biopharmaceuticals. Controlling glycosylation remains difficult due to intrinsic pathway complexity, limited online measurements, and a…

Optimization and Control · Mathematics 2026-02-03 Yingjie Ma , Jing Guo , Alexis B. Dubs , Krystian K. Ganko , Richard D. Braatz

Despite significant progress in alignment, large language models (LLMs) remain vulnerable to adversarial attacks that elicit harmful behaviors. Activation steering techniques offer a promising inference-time intervention approach, but…

Machine Learning · Computer Science 2026-01-28 Quy-Anh Dang , Chris Ngo

Learning representations for individual instances when only bag-level labels are available is a fundamental challenge in multiple instance learning (MIL). Recent works have shown promising results using contrastive self-supervised learning…

Computer Vision and Pattern Recognition · Computer Science 2023-07-13 Kangning Liu , Weicheng Zhu , Yiqiu Shen , Sheng Liu , Narges Razavian , Krzysztof J. Geras , Carlos Fernandez-Granda