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Convolutional neural networks can be trained to perform histology slide classification using weak annotations with multiple instance learning (MIL). However, given the paucity of labeled histology data, direct application of MIL can easily…

Computer Vision and Pattern Recognition · Computer Science 2019-11-05 Ming Y. Lu , Richard J. Chen , Jingwen Wang , Debora Dillon , Faisal Mahmood

Vein recognition has received increasing attention due to its high security and privacy. Recently, deep neural networks such as Convolutional neural networks (CNN) and Transformers have been introduced for vein recognition and achieved…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Huafeng Qin , Yiquan Wu , Mounim A. El-Yacoubi , Jun Wang , Guangxiang Yang

This paper focuses on the task of survival time analysis for lung cancer. Although much progress has been made in this problem in recent years, the performance of existing methods is still far from satisfactory. Traditional and some deep…

Computer Vision and Pattern Recognition · Computer Science 2022-11-08 Yujiao Wu , Yaxiong Wang , Xiaoshui Huang , Fan Yang , Sai Ho Ling , Steven Weidong Su

The versatility of multimodal deep learning holds tremendous promise for advancing scientific research and practical applications. As this field continues to evolve, the collective power of cross-modal analysis promises to drive…

Machine Learning · Computer Science 2025-05-15 Yifei Wang , Yunrui Li , Lin Liu , Pengyu Hong , Hao Xu

Lung cancer, particularly in its advanced stages, remains a leading cause of death globally. Though early detection via low-dose computed tomography (CT) is promising, the identification of high-risk factors crucial for surgical mode…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Xiaotong Fu , Xiangyu Meng , Jing Zhou , Ying Ji

Lung adenocarcinoma (LUAD) is characterized by substantial genetic heterogeneity, posing challenges in identifying reliable biomarkers for improved diagnosis and treatment. Tumor Mutational Burden (TMB) has traditionally been regarded as a…

Applications · Statistics 2024-11-08 Shaofei Zhao , Siming Huang , Kexuan Li , Weiyu Zhou , Lingli Yang , Shige Wang

Accurate survival prediction is crucial for development of precision cancer medicine, creating the need for new sources of prognostic information. Recently, there has been significant interest in exploiting routinely collected clinical and…

Machine Learning · Computer Science 2021-03-23 Sejin Kim , Michal Kazmierski , Benjamin Haibe-Kains

Automatic modulation classification (AMC) is a key technique for designing non-cooperative communication systems, and deep learning (DL) is applied effectively to AMC for improving classification accuracy. However, most of the DL-based AMC…

Signal Processing · Electrical Eng. & Systems 2023-04-25 Lantu Guo , Yu Wang , Yun Lin , Haitao Zhao , Guan Gui

In this paper, to collectively address the existing limitations on endoscopic diagnosis of Advanced Gastric Cancer (AGC) Tumors, for the first time, we propose (i) utilization and evaluation of our recently developed Vision-based Tactile…

Accurate cancer survival prediction requires integration of diverse data modalities that reflect the complex interplay between imaging, clinical parameters, and textual reports. However, existing multimodal approaches suffer from simplistic…

Machine Learning · Computer Science 2025-07-01 Aakash Tripathi , Asim Waqas , Matthew B. Schabath , Yasin Yilmaz , Ghulam Rasool

Accurate histological differentiation between adenocarcinoma (ADC) and squamous cell carcinoma (SCC) is critical for personalized treatment in non-small cell lung cancer (NSCLC). While [$^{18}$F]FDG PET/CT is a standard tool for the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Fatih Aksu , Laura Ciuffetti , Francesco Di Feola , Filippo Ruffini , Giulia Romoli , Fabrizia Gelardi , Arturo Chiti , Valerio Guarrasi , Paolo Soda

Large Language Models (LLMs) employ three popular training approaches: Masked Language Models (MLM), Causal Language Models (CLM), and Sequence-to-Sequence Models (seq2seq). However, each approach has its strengths and limitations, and…

Machine Learning · Computer Science 2025-02-18 Xuefeng Liu , Songhao Jiang , Bo Li , Rick Stevens

Background: Current research suggests that a small set of "driver" mutations are responsible for tumorigenesis while a larger body of "passenger" mutations occurs in the tumor but does not progress the disease. Due to recent pharmacological…

Genomics · Quantitative Biology 2013-10-30 Gregory Ryslik , Yuwei Cheng , Kei-Hoi Cheung , Robert Bjornson , Daniel Zelterman , Yorgo Modis , Hongyu Zhao

Major pathological response (pR) following neoadjuvant therapy is a clinically meaningful endpoint in non-small cell lung cancer, strongly associated with improved survival. However, accurate preoperative prediction of pR remains…

Lung cancer is highly lethal, emphasizing the critical need for early detection. However, identifying lung nodules poses significant challenges for radiologists, who rely heavily on their expertise for accurate diagnosis. To address this…

Image and Video Processing · Electrical Eng. & Systems 2023-10-17 Hossein Jafari , Karim Faez , Hamidreza Amindavar

Deep convolutional neural networks (CNNs) have been widely used in various medical imaging tasks. However, due to the intrinsic locality of convolution operation, CNNs generally cannot model long-range dependencies well, which are important…

Computer Vision and Pattern Recognition · Computer Science 2022-06-22 Xuxin Chen , Ke Zhang , Neman Abdoli , Patrik W. Gilley , Ximin Wang , Hong Liu , Bin Zheng , Yuchen Qiu

Automatic and precise medical image segmentation (MIS) is of vital importance for clinical diagnosis and analysis. Current MIS methods mainly rely on the convolutional neural network (CNN) or self-attention mechanism (Transformer) for…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Lanhu Wu , Miao Zhang , Yongri Piao , Zhenyan Yao , Weibing Sun , Feng Tian , Huchuan Lu

The rapid advancement of deep learning (DL) has transformed healthcare, particularly in cancer detection and diagnosis. DL surpasses traditional machine learning and human accuracy, making it a critical tool for identifying diseases.…

Image and Video Processing · Electrical Eng. & Systems 2025-04-21 Yassine Habchi , Hamza Kheddar , Yassine Himeur , Adel Belouchrani , Erchin Serpedin , Fouad Khelifi , Muhammad E. H. Chowdhury

Mutational signatures are patterns of somatic mutations in tumor genomes that provide insights into underlying mutagenic processes and cancer origin. Developing reliable methods for their estimation is of growing importance in cancer…

Applications · Statistics 2025-02-04 Blake Hansen , Isabella N. Grabski , Giovanni Parmigiani , Roberta De Vito

Recent advances in experimental methods have enabled researchers to collect data on thousands of analytes simultaneously. This has led to correlational studies that associated molecular measurements with diseases such as Alzheimer's, Liver,…

Quantitative Methods · Quantitative Biology 2024-05-20 Divyagna Bavikadi , Ayushi Agarwal , Shashank Ganta , Yunro Chung , Lusheng Song , Ji Qiu , Paulo Shakarian
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