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Multi-agent LLM frameworks are widely used to accelerate the development of agent systems powered by large language models (LLMs). These frameworks impose distinct architectural structures that govern how agents interact, store information,…

Artificial Intelligence · Computer Science 2026-02-04 Abdelghny Orogat , Ana Rostam , Essam Mansour

Autonomous agents powered by large language models (LLMs) perform complex tasks through long-horizon reasoning and tool interaction, where a fundamental trade-off arises between execution efficiency and reasoning robustness. Models at…

Computation and Language · Computer Science 2026-03-30 Wenbo Gao , Renxi Liu , Xian Wang , Fang Guo , Shuai Yang , Xi Chen , Hui-Ling Zhen , Hanting Chen , Weizhe Lin , Xiaosong Li , Yaoyuan Wang

Background: The surge in single-cell omics data exposes limitations in traditional, manually defined analysis workflows. AI agents offer a paradigm shift, enabling adaptive planning, executable code generation, traceable decisions, and…

Genomics · Quantitative Biology 2026-03-17 Yang Liu , Lu Zhou , Xiawei Du , Ruikun He , Xuguang Zhang , Rongbo Shen , Yixue Li

A standard ML model is commonly generated by a single method that specifies aspects such as architecture, initialization, training data and hyperparameters configuration. The presented work introduces a novel methodology allowing to define…

Machine Learning · Computer Science 2023-02-07 Andrea Gesmundo

Drug discovery frequently loses momentum when data, expertise, and tools are scattered, slowing design cycles. To shorten this loop we built a hierarchical, tool using agent framework that automates molecular optimisation. A Principal…

Machine Learning · Computer Science 2025-08-06 Atabey Ünlü , Phil Rohr , Ahmet Celebi

This review presents a comprehensive analysis of two emerging paradigms in AI-assisted software development: vibe coding and agentic coding. While both leverage large language models (LLMs), they differ fundamentally in autonomy,…

Software Engineering · Computer Science 2025-05-27 Ranjan Sapkota , Konstantinos I. Roumeliotis , Manoj Karkee

Motivation: Agent-based modeling is an indispensable tool for studying complex biological systems. However, existing simulators do not always take full advantage of modern hardware and often have a field-specific software design. Results:…

Modeling agent behavior is central to understanding the emergence of complex phenomena in multiagent systems. Prior work in agent modeling has largely been task-specific and driven by hand-engineering domain-specific prior knowledge. We…

Multiagent Systems · Computer Science 2018-08-02 Aditya Grover , Maruan Al-Shedivat , Jayesh K. Gupta , Yura Burda , Harrison Edwards

While individual components of agentic architectures have been studied in isolation, there remains limited empirical understanding of how different design dimensions interact within complex multi-agent systems. This study aims to address…

Artificial Intelligence · Computer Science 2026-01-07 Tara Bogavelli , Roshnee Sharma , Hari Subramani

Large language models (LLMs) and emerging agentic frameworks are beginning to transform single-cell biology by enabling natural-language reasoning, generative annotation, and multimodal data integration. However, progress remains fragmented…

Computation and Language · Computer Science 2025-11-25 Sajib Acharjee Dip , Adrika Zafor , Bikash Kumar Paul , Uddip Acharjee Shuvo , Muhit Islam Emon , Xuan Wang , Liqing Zhang

In this paper, we propose an Agentic Artificial Intelligence (AI) framework for wireless networks. The framework coordinates a pool of AI agents guided by Natural Language (NL) inputs from a human operator. At its core, the super agent is…

Networking and Internet Architecture · Computer Science 2026-04-07 Md Arafat Habib , Medhat Elsayed , Majid Bavand , Pedro Enrique Iturria Rivera , Yigit Ozcan , Melike Erol-Kantarci

Spatial patterns arising from the collective behavior of individual agents are present across biological systems. While agent-based models offer a natural framework for uncovering unknown agent (e.g., cell) interactions, these stochastic…

Quantitative Methods · Quantitative Biology 2026-05-19 Yue Liu , Alexandria Volkening

Autonomous materials research systems allow scientists to fail smarter, learn faster, and spend less resources in their studies. As these systems grow in number, capability, and complexity, a new challenge arises - how will they work…

Multiagent Systems · Computer Science 2023-03-21 A. Gilad Kusne , Austin McDannald

Agentic AI applications increasingly rely on multiple agents with distinct roles, specialized tools, and access to memory layers to solve complex tasks -- closely resembling service-oriented architectures. Yet, in the rapid evolving…

Software Engineering · Computer Science 2025-10-15 Alessandro Cornacchia , Vaastav Anand , Muhammad Bilal , Zafar Qazi , Marco Canini

Despite rapid progress in large language model (LLM)-based multi-agent systems, current benchmarks fall short in evaluating their scalability, robustness, and coordination capabilities in complex, dynamic, real-world tasks. Existing…

Multiagent Systems · Computer Science 2025-12-15 Jonathan Hyun , Nicholas R Waytowich , Boyuan Chen

Recent advances in large language models (LLMs) have opened new avenues for applying multi-agent systems in very large-scale simulations. However, there remain several challenges when conducting multi-agent simulations with existing…

Multiagent Systems · Computer Science 2024-10-29 Xuchen Pan , Dawei Gao , Yuexiang Xie , Yushuo Chen , Zhewei Wei , Yaliang Li , Bolin Ding , Ji-Rong Wen , Jingren Zhou

Autonomous agents driven by Large Language Models (LLMs) offer enormous potential for automation. Early proof of this technology can be found in various demonstrations of agents solving complex tasks, interacting with external systems to…

In recent years, agentic workflows have been widely applied to solve complex human tasks. However, existing workflow construction still faces key challenges, including human-dependent workflow construction, the lack of graph-level execution…

Artificial Intelligence · Computer Science 2026-05-15 Mingda Zhang , Wenjin Liu , Tiesunlong Shen , Qika Lin , Rui Mao , Erik Cambria , Xiaoying Tang , Haoran Luo

We introduce GenAgent, unifying visual understanding and generation through an agentic multimodal model. Unlike unified models that face expensive training costs and understanding-generation trade-offs, GenAgent decouples these capabilities…

Computer Vision and Pattern Recognition · Computer Science 2026-01-29 Kaixun Jiang , Yuzheng Wang , Junjie Zhou , Pandeng Li , Zhihang Liu , Chen-Wei Xie , Zhaoyu Chen , Yun Zheng , Wenqiang Zhang

As AI agents evolve, the community is rapidly shifting from single Large Language Models (LLMs) to Multi-Agent Systems (MAS) to overcome cognitive bottlenecks in automated research. However, the optimal multi-agent coordination framework…

Multiagent Systems · Computer Science 2026-05-12 Yang Shen , Zhenyi Yi , Ziyi Zhao , Lijun Sun , Dongyang Li , Chin-Teng Lin , Yuhui Shi
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