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Machine learning for tabular data remains constrained by poor schema generalization, a challenge rooted in the lack of semantic understanding of structured variables. This challenge is particularly acute in domains like clinical medicine,…

Machine Learning · Computer Science 2026-05-05 Hongxi Mao , Wei Zhou , Mengting Jia , Tao Fang , Huan Gao , Bin Zhang , Shangyang Li

Synthetic data generation using large language models (LLMs) demonstrates substantial promise in addressing biomedical data challenges and shows increasing adoption in biomedical research. This study systematically reviews recent advances…

Computation and Language · Computer Science 2026-02-18 Hanshu Rao , Weisi Liu , Haohan Wang , I-Chan Huang , Zhe He , Xiaolei Huang

Cold-Start Active Learning (CSAL) aims to select informative samples for annotation without prior knowledge, which is important for improving annotation efficiency and model performance under a limited annotation budget in medical image…

Computer Vision and Pattern Recognition · Computer Science 2025-10-13 Ning Zhu , Xiaochuan Ma , Shaoting Zhang , Guotai Wang

Early detection of preventable diseases is important for better disease management, improved inter-ventions, and more efficient health-care resource allocation. Various machine learning approacheshave been developed to utilize information…

Machine Learning · Computer Science 2018-08-16 Jingshu Liu , Zachariah Zhang , Narges Razavian

Generating clinical reports that summarize abnormal patterns, diagnostic findings, and clinical interpretations from long-term EEG recordings remains labor-intensive. We present CELM, the first clinical EEG-to-Language foundation model…

Machine Learning · Computer Science 2026-05-15 Jathurshan Pradeepkumar , Zheng Chen , Jimeng Sun

This study proposes a risk prediction method based on a Multi-Scale Temporal Alignment Network (MSTAN) to address the challenges of temporal irregularity, sampling interval differences, and multi-scale dynamic dependencies in Electronic…

Machine Learning · Computer Science 2025-11-27 Wei-Chen Chang , Lu Dai , Ting Xu

Clinical natural language processing (NLP) is increasingly in demand in both clinical research and operational practice. However, most of the state-of-the-art solutions are transformers-based and require high computational resources,…

Computation and Language · Computer Science 2025-04-18 Jianlin Shi , Qiwei Gan , Elizabeth Hanchrow , Annie Bowles , John Stanley , Adam P. Bress , Jordana B. Cohen , Patrick R. Alba

Electronic Patient Record (EPR) systems contain valuable clinical information, but much of it is trapped in unstructured text, limiting its use for research and decision-making. Large language models can extract such information but require…

LLMs for clinical decision support often fail under small but clinically meaningful input shifts such as masking a symptom or negating a finding, despite high performance on static benchmarks. These reasoning failures frequently go…

Machine Learning · Computer Science 2025-07-30 Raj Krishnan Vijayaraj

Clinical practice guidelines (CPGs) provide evidence-based recommendations for patient care; however, integrating them into Artificial Intelligence (AI) remains challenging. Previous approaches, such as rule-based systems, face significant…

Artificial Intelligence · Computer Science 2026-01-08 Ruiqi Deng , Geoffrey Martin , Tony Wang , Gongbo Zhang , Yi Liu , Chunhua Weng , Yanshan Wang , Justin F Rousseau , Yifan Peng

General-purpose Large Vision-Language Models (LVLMs), despite their massive scale, often falter in dermatology due to "diffuse attention" - the inability to disentangle subtle pathological lesions from background noise. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Lijun Liu , Linwei Chen , Zhishou Zhang , Meng Tian , Hengfu Cui , Ruiyang Li , Zhaocheng Liu , Qiang Ju , Qianxi Li , Hong-Yu Zhou

Large Language Models (LLMs) are increasingly used for clinical decision support, where hallucinations and unsafe suggestions may pose direct risks to patient safety. These risks are hard to assess: subtle clinical errors are often missed…

Computation and Language · Computer Science 2026-05-14 Yinzhu Chen , Abdine Maiga , Hossein A. Rahmani , Emine Yilmaz

Importance: We introduce a novel Retrieval Augmented Generation (RAG)-Large Language Model (LLM) framework as a Clinical Decision Support Systems (CDSS) to support safe medication prescription. Objective: To evaluate the efficacy of…

This paper presents the development and evaluation of a Retrieval-Augmented Generation (RAG) system for querying the United Kingdom's National Institute for Health and Care Excellence (NICE) clinical guidelines using Large Language Models…

Clinical Text Notes (CTNs) contain physicians' reasoning process, written in an unstructured free text format, as they examine and interview patients. In recent years, several studies have been published that provide evidence for the…

Computation and Language · Computer Science 2022-08-19 Hlynur D. Hlynsson , Steindór Ellertsson , Jón F. Daðason , Emil L. Sigurdsson , Hrafn Loftsson

Semantic feature norms have been foundational in the study of human conceptual knowledge, yet traditional methods face trade-offs between concept/feature coverage and verifiability of quality due to the labor-intensive nature of norming…

Computation and Language · Computer Science 2025-05-19 Siddharth Suresh , Kushin Mukherjee , Tyler Giallanza , Xizheng Yu , Mia Patil , Jonathan D. Cohen , Timothy T. Rogers

Recent advancements in Large Language Models (LLMs) have played a significant role in reducing human workload across various domains, a trend that is increasingly extending into the medical field. In this paper, we propose an automated…

Computation and Language · Computer Science 2026-03-30 Kyomin Hwang , Nojun Kwak

Clinical notes are often stored in unstructured or semi-structured formats after extraction from electronic medical record (EMR) systems, which complicates their use for secondary analysis and downstream clinical applications. Reliable…

Computation and Language · Computer Science 2025-12-30 Risha Surana , Adrian Law , Sunwoo Kim , Rishab Sridhar , Angxiao Han , Peiyu Hong

Existing text representations such as embeddings and bag-of-words are not suitable for rule learning due to their high dimensionality and absent or questionable feature-level interpretability. This article explores whether large language…

Machine Learning · Computer Science 2025-10-02 Vojtěch Balek , Lukáš Sýkora , Vilém Sklenák , Tomáš Kliegr

Electronic health records (EHRs) house crucial patient data in clinical notes. As these notes grow in volume and complexity, manual extraction becomes challenging. This work introduces a natural language interface using large language…

Information Retrieval · Computer Science 2024-07-03 Ran Elgedawy , Ioana Danciu , Maria Mahbub , Sudarshan Srinivasan