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Large language models (LLMs) are entering clinician workflows, yet evaluations rarely measure how clinician reasoning shapes model behavior during clinical interactions. We combined 61 New England Journal of Medicine Case Records with 92…

The advent of large language models (LLMs) has opened new avenues for analyzing complex, unstructured data, particularly within the medical domain. Electronic Health Records (EHRs) contain a wealth of information in various formats,…

Information Retrieval · Computer Science 2025-06-10 Wu Hao Ran , Xi Xi , Furong Li , Jingyi Lu , Jian Jiang , Hui Huang , Yuzhuan Zhang , Shi Li

A significant amount of data held in Oncology Electronic Medical Records (EMRs) is contained in unstructured provider notes -- including but not limited to the chemotherapy (or cancer treatment) outcome, different biomarkers, the tumor's…

Aiming at the limitations of traditional medical decision system in processing large-scale heterogeneous medical data and realizing highly personalized recommendation, this paper introduces a personalized medical decision algorithm…

Machine Learning · Computer Science 2024-05-29 Yafeng Yan , Shuyao He , Zhou Yu , Jiajie Yuan , Ziang Liu , Yan Chen

In the rapidly evolving field of Explainable Natural Language Processing (NLP), textual explanations, i.e., human-like rationales, are pivotal for explaining model predictions and enriching datasets with interpretable labels. Traditional…

Computation and Language · Computer Science 2025-11-12 Mahdi Dhaini , Juraj Vladika , Ege Erdogan , Zineb Attaoui , Gjergji Kasneci

Longitudinal information in radiology reports refers to the sequential tracking of findings across multiple examinations over time, which is crucial for monitoring disease progression and guiding clinical decisions. Many recent automated…

Computation and Language · Computer Science 2026-01-26 Xinyi Wang , Grazziela Figueredo , Ruizhe Li , Xin Chen

Software fault prediction (SFP) is a critical task in software engineering, enabling early identification of faults in modules to improve software quality and reduce maintenance costs. This research investigates the combined effects of…

Software Engineering · Computer Science 2026-05-19 Ahmad Nauman Ghazi , Nagajyothi Devarapalli , Ashir Javeed , Sadi Alawadi , Fahed Alkhabbas , Khalid AlKharabsheh

Recent advancements in large language models (LLMs) have shown promise in feature engineering for tabular data, but concerns about their reliability persist, especially due to variability in generated outputs. We introduce a multi-level…

Machine Learning · Computer Science 2025-10-01 Yebin Lim , Susik Yoon

We proposed a fully automatic workflow for glioblastoma (GBM) survival prediction using deep learning (DL) methods. 285 glioma (210 GBM, 75 low-grade glioma) patients were included. 163 of the GBM patients had overall survival (OS) data.…

Medical Physics · Physics 2021-07-07 Jie Fu , Kamal Singhrao , Xinran Zhong , Yu Gao , Sharon Qi , Yingli Yang , Dan Ruan , John H Lewis

Matching patients to clinical trials is a key unsolved challenge in bringing new drugs to market. Today, identifying patients who meet a trial's eligibility criteria is highly manual, taking up to 1 hour per patient. Automated screening is…

Computation and Language · Computer Science 2024-04-11 Michael Wornow , Alejandro Lozano , Dev Dash , Jenelle Jindal , Kenneth W. Mahaffey , Nigam H. Shah

Clinical notes recorded during a patient's perioperative journey holds immense informational value. Advances in large language models (LLMs) offer opportunities for bridging this gap. Using 84,875 pre-operative notes and its associated…

Computation and Language · Computer Science 2025-04-03 Charles Alba , Bing Xue , Joanna Abraham , Thomas Kannampallil , Chenyang Lu

Objective: To develop and evaluate machine learning (ML) models for predicting length of stay (LOS) in elective spine surgery, with a focus on the benefits of temporal modeling and model interpretability. Materials and Methods: We compared…

Machine Learning · Computer Science 2025-07-17 Ha Na Cho , Sairam Sutari , Alexander Lopez , Hansen Bow , Kai Zheng

The diagnosis of oral diseases presents a problematic clinical challenge, characterized by a wide spectrum of pathologies with overlapping symptomatology. To address this, we developed Clinical Semantic Intelligence (CSI), a novel…

Artificial Intelligence · Computer Science 2025-07-22 Mohammad Mashayekhi , Sara Ahmadi Majd , Arian AmirAmjadi , Parsa Hosseini

Recent work on predicting patient outcomes in the Intensive Care Unit (ICU) has focused heavily on the physiological time series data, largely ignoring sparse data such as diagnoses and medications. When they are included, they are usually…

Machine Learning · Computer Science 2021-01-12 Emma Rocheteau , Catherine Tong , Petar Veličković , Nicholas Lane , Pietro Liò

Radiology report generation (RRG) is commonly formulated as a single-path generation task, where a multimodal large language model (MLLM) produces one decoded report as the final output. While recent progress has largely been driven by…

Computation and Language · Computer Science 2026-05-29 Xi Zhang , Yingshu Li , Zaiqiao Meng , Jake Lever , Edmond S. L. Ho

LLM-based agents have emerged as transformative tools capable of executing complex tasks through iterative planning and action, achieving significant advancements in understanding and addressing user needs. Yet, their effectiveness remains…

Human-Computer Interaction · Computer Science 2025-08-26 Mithat Can Ozgun , Jiahuan Pei , Koen Hindriks , Lucia Donatelli , Qingzhi Liu , Junxiao Wang

The 7-point checklist (7PCL) is a widely used diagnostic tool in dermoscopy for identifying malignant melanoma by assigning point values to seven specific attributes. However, the traditional 7PCL is limited to distinguishing between…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Yuheng Wang , Tianze Yu , Jiayue Cai , Sunil Kalia , Harvey Lui , Z. Jane Wang , Tim K. Lee

Clinical decision-making depends on expert reasoning, which is guided by standardized, evidence-based guidelines. However, translating these guidelines into automated clinical decision support systems risks inaccuracy and importantly, loss…

Counterfactual explanations (CFs) offer human-centric insights into machine learning predictions by highlighting minimal changes required to alter an outcome. Therefore, CFs can be used as (i) interventions for abnormality prevention and…

Artificial Intelligence · Computer Science 2025-09-09 Shovito Barua Soumma , Asiful Arefeen , Stephanie M. Carpenter , Melanie Hingle , Hassan Ghasemzadeh

Human Activity Recognition using wearable inertial sensors is foundational to healthcare monitoring, fitness analytics, and context-aware computing, yet its deployment is hindered by cross-user variability arising from heterogeneous…

Machine Learning · Computer Science 2026-03-18 Xiaozhou Ye , Feng Jiang , Zihan Wang , Xiulai Wang , Yutao Zhang , Kevin I-Kai Wang
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