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Recently, the cross-modal pre-training task has been a hotspot because of its wide application in various down-streaming researches including retrieval, captioning, question answering and so on. However, exiting methods adopt a one-stream…

Computer Vision and Pattern Recognition · Computer Science 2022-07-11 Keyu Wen , Zhenshan Tan , Qingrong Cheng , Cheng Chen , Xiaodong Gu

Predicting compound-protein affinity is critical for accelerating drug discovery. Recent progress made by machine learning focuses on accuracy but leaves much to be desired for interpretability. Through molecular contacts underlying…

Biomolecules · Quantitative Biology 2020-01-01 Mostafa Karimi , Di Wu , Zhangyang Wang , Yang Shen

The global reach of social media has amplified the spread of hateful content, including implicit sexism, which is often overlooked by conventional detection methods. In this work, we introduce an Adaptive Supervised Contrastive lEarning…

Computation and Language · Computer Science 2025-07-09 Mohammad Zia Ur Rehman , Aditya Shah , Nagendra Kumar

Self-supervised contrastive learning heavily relies on the view variance brought by data augmentation, so that it can learn a view-invariant pre-trained representation. Beyond increasing the view variance for contrast, this work focuses on…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Yong Zhang , Rui Zhu , Shifeng Zhang , Xu Zhou , Shifeng Chen , Xiaofan Chen

The paradigm of large-scale pre-training followed by downstream fine-tuning has been widely employed in various object detection algorithms. In this paper, we reveal discrepancies in data, model, and task between the pre-training and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-15 Ming Li , Jie Wu , Xionghui Wang , Chen Chen , Jie Qin , Xuefeng Xiao , Rui Wang , Min Zheng , Xin Pan

Beyond the success of Contrastive Language-Image Pre-training (CLIP), recent trends mark a shift toward exploring the applicability of lightweight vision-language models for resource-constrained scenarios. These models often deliver…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Chu Myaet Thwal , Ye Lin Tun , Minh N. H. Nguyen , Eui-Nam Huh , Choong Seon Hong

Given a similarity metric, contrastive methods learn a representation in which examples that are similar are pushed together and examples that are dissimilar are pulled apart. Contrastive learning techniques have been utilized extensively…

Machine Learning · Computer Science 2023-07-07 Emily Mu , John Guttag , Maggie Makar

Contrastive learning has demonstrated great success in representation learning, especially for image classification tasks. However, there is still a shortage in studies targeting regression tasks, and more specifically applications on…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Mohamad Dhaini , Paul Honeine , Maxime Berar , Antonin Van Exem

An effective framework for learning 3D representations for perception tasks is distilling rich self-supervised image features via contrastive learning. However, image-to point representation learning for autonomous driving datasets faces…

Computer Vision and Pattern Recognition · Computer Science 2023-03-27 Anas Mahmoud , Jordan S. K. Hu , Tianshu Kuai , Ali Harakeh , Liam Paull , Steven L. Waslander

In the face of rapidly accumulating genomic data, our understanding of the RNA regulatory code remains incomplete. Recent self-supervised methods in other domains have demonstrated the ability to learn rules underlying the data-generating…

Machine Learning · Computer Science 2023-10-18 Philip Fradkin , Ruian Shi , Bo Wang , Brendan Frey , Leo J. Lee

Modern Review Helpfulness Prediction systems are dependent upon multiple modalities, typically texts and images. Unfortunately, those contemporary approaches pay scarce attention to polish representations of cross-modal relations and tend…

Computation and Language · Computer Science 2026-05-13 Thong Nguyen , Xiaobao Wu , Anh-Tuan Luu , Cong-Duy Nguyen , Zhen Hai , Lidong Bing

Despite recent success of self-supervised based contrastive learning model for 3D point clouds representation, the adversarial robustness of such pre-trained models raised concerns. Adversarial contrastive learning (ACL) is considered an…

Computer Vision and Pattern Recognition · Computer Science 2022-09-16 Junxuan Huang , Yatong An , Lu cheng , Bai Chen , Junsong Yuan , Chunming Qiao

Medical images and reports offer invaluable insights into patient health. The heterogeneity and complexity of these data hinder effective analysis. To bridge this gap, we investigate contrastive learning models for cross-domain retrieval,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Demetrio Deanda , Yuktha Priya Masupalli , Jeong Yang , Young Lee , Zechun Cao , Gongbo Liang

Since the meaning representations are detailed and accurate annotations which express fine-grained sequence-level semtantics, it is usually hard to train discriminative semantic parsers via Maximum Likelihood Estimation (MLE) in an…

Computation and Language · Computer Science 2023-01-20 Shan Wu , Chunlei Xin , Bo Chen , Xianpei Han , Le Sun

The discovery of novel drug target (DT) interactions is an important step in the drug development process. The majority of computer techniques for predicting DT interactions have focused on binary classification, with the goal of…

Machine Learning · Computer Science 2023-03-22 Partho Ghosh , Md. Aynal Haque

We study adapting trained object detectors to unseen domains manifesting significant variations of object appearance, viewpoints and backgrounds. Most current methods align domains by either using image or instance-level feature alignment…

Computer Vision and Pattern Recognition · Computer Science 2021-10-04 Muhammad Akhtar Munir , Muhammad Haris Khan , M. Saquib Sarfraz , Mohsen Ali

The computational drug repositioning aims to discover new uses for marketed drugs, which can accelerate the drug development process and play an important role in the existing drug discovery system. However, the number of validated…

Machine Learning · Computer Science 2022-06-02 Xinxing Yang , Genke Yang , Jian Chu

Given a query composed of a reference image and a relative caption, the Composed Image Retrieval goal is to retrieve images visually similar to the reference one that integrates the modifications expressed by the caption. Given that recent…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Alberto Baldrati , Marco Bertini , Tiberio Uricchio , Alberto del Bimbo

Mask-guided matting networks have achieved significant improvements and have shown great potential in practical applications in recent years. However, simply learning matting representation from synthetic and lack-of-real-world-diversity…

Computer Vision and Pattern Recognition · Computer Science 2024-03-29 Weihao Jiang , Zhaozhi Xie , Yuxiang Lu , Longjie Qi , Jingyong Cai , Hiroyuki Uchiyama , Bin Chen , Yue Ding , Hongtao Lu

Dense retrievers have achieved impressive performance, but their demand for abundant training data limits their application scenarios. Contrastive pre-training, which constructs pseudo-positive examples from unlabeled data, has shown great…

Information Retrieval · Computer Science 2023-06-07 Yibin Lei , Liang Ding , Yu Cao , Changtong Zan , Andrew Yates , Dacheng Tao