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We study the use of "sign $\alpha$-stable random projections" (where $0<\alpha\leq 2$) for building basic data processing tools in the context of large-scale machine learning applications (e.g., classification, regression, clustering, and…

Machine Learning · Statistics 2015-04-29 Ping Li

The growing complexity of Cyber-Physical Systems (CPS) and challenges in ensuring safety and security have led to the increasing use of deep learning methods for accurate and scalable anomaly detection. However, machine learning (ML) models…

Machine Learning · Computer Science 2022-05-04 Xugui Zhou , Maxfield Kouzel , Homa Alemzadeh

Large language models (LLMs) are increasingly used to generate labels from radiology reports to enable large-scale AI evaluation. However, label noise from LLMs can introduce bias into performance estimates, especially under varying disease…

We conducted a survey of 67 graduate students enrolled in the Privacy and Security in Healthcare course at Indiana University Purdue University Indianapolis. This was done to measure user preference and their understanding of usability and…

Cryptography and Security · Computer Science 2021-02-24 Saptarshi Purkayastha , Shreya Goyal , Bolu Oluwalade , Tyler Phillips , Huanmei Wu , Xukai Zou

A central question in machine learning is how reliable the predictions of a trained model are. Reliability includes the identification of instances for which a model is likely not to be trusted based on an analysis of the learning system…

Quantum Physics · Physics 2026-01-21 Marie Kempkes , Jakob Spiegelberg , Evert van Nieuwenburg , Vedran Dunjko

In medicine, both ethical and monetary costs of incorrect predictions can be significant, and the complexity of the problems often necessitates increasingly complex models. Recent work has shown that changing just the random seed is enough…

This study investigates uncertainty quantification in large language models (LLMs) for medical applications, emphasizing both technical innovations and philosophical implications. As LLMs become integral to clinical decision-making,…

Artificial Intelligence · Computer Science 2025-04-08 Zahra Atf , Seyed Amir Ahmad Safavi-Naini , Peter R. Lewis , Aref Mahjoubfar , Nariman Naderi , Thomas R. Savage , Ali Soroush

We ascertain and compare the performances of AutoML tools on large, highly imbalanced healthcare datasets. We generated a large dataset using historical administrative claims including demographic information and flags for disease codes in…

Tsetlin Machines (TMs) have emerged as a compelling alternative to conventional deep learning methods, offering notable advantages such as smaller memory footprint, faster inference, fault-tolerant properties, and interpretability. Although…

Machine Learning · Computer Science 2024-11-14 K. Darshana Abeyrathna , Sara El Mekkaoui , Andreas Hafver , Christian Agrell

Clinical decision requires reasoning in the presence of imperfect data. DTs are a well-known decision support tool, owing to their interpretability, fundamental in safety-critical contexts such as medical diagnosis. However, learning DTs…

Biomarkers are critical tools in the diagnosis and monitoring of neurodegenerative diseases. Reliable quantification depends on assay validity, especially the demonstration of parallelism between diluted biological samples and the assay's…

Quantitative Methods · Quantitative Biology 2025-11-26 Axel Petzold , Joachim Pum , David P Crabb

Uncertainty estimation, which provides a means of building explainable neural networks for medical imaging applications, have mostly been studied for single deep learning models that focus on a specific task. In this paper, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Leonhard F. Feiner , Martin J. Menten , Kerstin Hammernik , Paul Hager , Wenqi Huang , Daniel Rueckert , Rickmer F. Braren , Georgios Kaissis

To facilitate healthcare delivery, language models (LMs) have significant potential for clinical prediction tasks using electronic health records (EHRs). However, in these high-stakes applications, unreliable decisions can result in high…

Computation and Language · Computer Science 2024-11-07 Zizhang Chen , Peizhao Li , Xiaomeng Dong , Pengyu Hong

Performance uncertainty quantification is essential for reliable validation and eventual clinical translation of medical imaging artificial intelligence (AI). Confidence intervals (CIs) play a central role in this process by indicating how…

Methods for medical image registration infer geometric transformations that align pairs/groups of images by maximising an image similarity metric. This problem is ill-posed as several solutions may have equivalent likelihoods, also…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Aisha L. Shuaibu , Ivor J. A. Simpson

Fine-tuning a general-purpose large language model (LLM) for a specific domain or task has become a routine procedure for ordinary users. However, fine-tuning is known to remove the safety alignment features of the model, even when the…

Computation and Language · Computer Science 2025-06-23 Kathleen C. Fraser , Hillary Dawkins , Isar Nejadgholi , Svetlana Kiritchenko

Landslides are a recurring, widespread hazard. Preparation and mitigation efforts can be aided by a high-quality, large-scale dataset that covers global at-risk areas. Such a dataset currently does not exist and is impossible to construct…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Savinay Nagendra , Chaopeng Shen , Daniel Kifer

Large language models used for clinical abstraction are sensitive to prompt wording, yet most work treats prompts as fixed and studies uncertainty in isolation. We argue these should be treated jointly. Across two clinical tasks (MedAlign…

Computation and Language · Computer Science 2026-02-02 Arinbjörn Kolbeinsson , Daniel Timbie , Sajjan Narsinghani , Sanjay Hariharan

Many scientific and engineering applications require fitting regression models that are nonlinear in the parameters. Advances in computer hardware and software in recent decades have made it easier to fit such models. Relative to fitting…

Methodology · Statistics 2024-03-20 Peng Liu , William Q. Meeker

This paper proposes a model validation method that incorporates error due to numerical procedures. Two identified models for Sine Map and Duffing-Ueda Circuit systems have been investigated. The indexes RMSE and MAPE have been applied. We…

Signal Processing · Electrical Eng. & Systems 2017-11-22 Igor C. Silva , Gabriel H. A. Silva , Samir A. M. Martins , Erivelton G. Nepomuceno