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The refractory period and conduction delay of the atrioventricular (AV) node play a crucial role in regulating the heart rate during atrial fibrillation (AF). Beat-to-beat variations in these properties are known to be induced by the…

Tissues and Organs · Quantitative Biology 2025-06-25 Mattias Karlsson , Felix Plappert , Pyotr G Platonov , Sten Östenson , Mikael Wallman , Frida Sandberg

We present an optimization strategy for atom-specific spin-polarization constants within the spin-polarized GFN2-xTB framework, aiming to enhance the accuracy of molecular simulations. We compare a sequential and global optimization of spin…

Objective: The design of an Artificial Pancreas (AP) to regulate blood glucose levels requires reliable control methods. Model Predictive Control has emerged as a promising approach for glycemia control. However, model--based control…

Optimization and Control · Mathematics 2022-02-02 Claudia Lopez-Zazueta , Øyvind Stavdahl , Anders Lyngvi Fougner

The critical current density has been measured on single crystals of Ru substituted BaFe2As2 superconductor at several temperatures and in fields up to 16 T. The magnetisation versus field isotherms reveal the occurrence of a clear second…

Superconductivity · Physics 2012-12-03 Shilpam Sharma , K. Vinod , C. S. Sundar , A. Bharathi

A discrete electrostatic/diffusion model has been developed to describe the selective permeation of ion channels, based on ionic Coulomb blockade (ICB) and quantised dehydration (QD). It has been applied to describe selectivity phenomena…

Global sensitivity analysis is the main quantitative technique for identifying the most influential input variables in a numerical simulation model. In particular when the inputs are independent, Sobol' sensitivity indices attribute a…

Statistics Theory · Mathematics 2021-01-15 Sébastien da Veiga

Fundamentally, action potentials in the squid axon are consequence of the entrance of sodium ions during the depolarization of the rising phase of the spike mediated by the outflow of potassium ions during the hyperpolarization of the…

Neurons and Cognition · Quantitative Biology 2012-11-29 Abdelmalik Moujahid , Alicia D'Anjou

Phase and time delays of atomic above-threshold ionization are usually experimentally explored by the reconstruction of attosecond harmonic beating by interference of two-photon transitions (RABBIT) technique. Theoretical studies of RABBIT…

Atomic Physics · Physics 2024-03-25 Sebastián D. López , Matias L. Ocello , Diego G. Arbó

Attosecond ionization time-delays at photoelectron energies above typically 10 eV are usually interpreted using the so called asymptotic approximation as a sum of the atomic or molecular delays with a universal laser-induced contribution.…

We theoretically study the superradiant phase transition (SPT) in an indirect Rabi model, where both a two-level system and a single mode bosonic field couple to an auxiliary bosonic field. We find that the indirect spin-field coupling…

Quantum Physics · Physics 2023-03-15 Wen Huang , Ying Wu , Xin-You Lü

Superconducting (SC) diodes are key passive building blocks for future SC electronics. However, realizing their active counterparts is essential for functional logic. Here, we demonstrate deterministic nonvolatile electrical switching of…

Superconductivity · Physics 2026-01-27 Jiajun Ma , Jingyi He , Qiong Qin , Tian Le , Zhiwei Wang , Jie Wu , Congjun Wu , Xiao Lin

Synchronized rhythmic oscillatory activity in the beta frequency band in the basal ganglia (BG) is a hallmark of Parkinson's disease (PD). Recent experiments and theoretical studies have demonstrated the crucial roles of T-type and L-type…

Neurons and Cognition · Quantitative Biology 2026-01-09 Choongseok Park , Leonid L. Rubchinsky , Sungwoo Ahn

During early development, waves of activity propagate across the retina and play a key role in the proper wiring of the early visual system. During the stage II these waves are triggered by a transient network of neurons, called Starburst…

Neurons and Cognition · Quantitative Biology 2018-12-19 Dora Matzakou-Karvouniari , Lionel Gil , Elaine Orendorff , Olivier Marre , Serge Picaud , Bruno Cessac

Many types of neurons exhibit spike rate adaptation, mediated by intrinsic slow $\mathrm{K}^+$-currents, which effectively inhibit neuronal responses. How these adaptation currents change the relationship between in-vivo like fluctuating…

Neurons and Cognition · Quantitative Biology 2013-11-08 Josef Ladenbauer , Moritz Augustin , Klaus Obermayer

This study employs extensive three-dimensional direct numerical simulations (DNS) to investigate the influence of blood non-Newtonian behaviors on the hemodynamics around a bileaflet mechanical heart valve under both steady inflow and…

Fluid Dynamics · Physics 2024-05-01 A. Chauhan , C. Sasmal

Atrial fibrillation (AF) is associated with cognitive impairment/dementia, independently of clinical cerebrovascular events (stroke/TIA). One of the plausible mechanisms is the occurrence of AF-induced transient critical hemodynamic events;…

Medical Physics · Physics 2019-03-11 Andrea Saglietto , Stefania Scarsoglio , Luca Ridolfi , Fiorenzo Gaita , Matteo Anselmino

Risken's matrix continued fraction method is used to solve the Fokker-Planck equation to calculate particle current in an inertial symmetric (sinusoidal) periodic potential under the action of a constant force. The particle moves in a…

Statistical Mechanics · Physics 2008-07-18 W. L. Reenbohn , Mangal C. Mahato

We calculate Shannon information entropy of trapped interacting bosons in both the position and momentum spaces, $S_r$ and $S_k$ respectively. The total entropy maintains the fuctional form $S=a + b \ln N$ for repulsive bosons. At the…

Quantum Gases · Physics 2013-01-25 Sudip Kumar Haldar , Barnali Chakrabarti

In the high density low temperature limit, Quantum Chromodynamics (QCD) exhibits a transition to a phase characterized by color superconductivity and by energy gaps in the fermion spectra. Under specific circumstances the gap parameter has…

High Energy Physics - Phenomenology · Physics 2009-11-07 R. Casalbuoni , R. Gatto , M. Mannarelli , G. Nardulli

Although atrial fibrillation (AF), a common arrhythmia, frequently presents in patients with underlying valvular disease, its hemodynamic contributions are not fully understood. The present work aimed to computationally study how physical…