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This paper introduces $\Delta$-MILP, a powerful variant of the mixed-integer linear programming (MILP) optimization framework to solve NASA's Deep Space Network (DSN) scheduling problem. This work is an extension of our original MILP…

Optimization and Control · Mathematics 2022-04-27 Thomas Claudet , Ryan Alimo , Edwin Goh , Mark Johnston , Ramtin Madani , Brian Wilson

A decision support system relies on frequent re-solving of similar problem instances. While the general structure remains the same in corresponding applications, the input parameters are updated on a regular basis. We propose a generative…

Optimization and Control · Mathematics 2021-02-04 Lovis Anderson , Mark Turner , Thorsten Koch

Finding the most probable (MAP) model in SRL frameworks such as Markov logic and Problog can, in principle, be solved by encoding the problem as a `grounded-out' mixed integer program (MIP). However, useful first-order structure disappears…

Artificial Intelligence · Computer Science 2015-07-14 James Cussens

Mixed-integer programming (MIP) extends linear programming by incorporating both continuous and integer decision variables, making it widely used in production planning, logistics scheduling, and resource allocation. However, MIP remains…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-14 Jinyu Zhang , Di Huang , Yue Liu , Shuo Wang , Zhenyu Pu , Zhiyuan Liu

The floor layout problem (FLP) tasks a designer with positioning a collection of rectangular boxes on a fixed floor in such a way that minimizes total communication costs between the components. While several mixed integer programming (MIP)…

Optimization and Control · Mathematics 2017-04-12 Joey Huchette , Santanu S. Dey , Juan Pablo Vielma

We propose a machine learning approach for quickly solving Mixed Integer Programs (MIP) by learning to prioritize a set of decision variables, which we call pseudo-backdoors, for branching that results in faster solution times.…

Machine Learning · Computer Science 2021-06-10 Aaron Ferber , Jialin Song , Bistra Dilkina , Yisong Yue

Uncertainty in surgery durations continues to be difficult to account for in operating room scheduling. In particular, it remains complex to accurately incorporate uncertainty in surgical overtime constraints within mixed-integer linear…

Optimization and Control · Mathematics 2026-04-29 Cindy Pistorius , J. Theresia van Essen

This paper addresses the problem of tightening the mixed-integer linear programming (MILP) formulation for continuous piecewise linear (CPWL) approximations of data sets in arbitrary dimensions. The MILP formulation leverages the…

Optimization and Control · Mathematics 2026-01-08 Quentin Ploussard , Xiang Li , Matija Pavičević

Covering problems are well-studied in the domain of Operations Research, and, more specifically, in Location Science. When the location space is a network, the most frequent assumption is to consider the candidate facility locations, the…

Optimization and Control · Mathematics 2023-01-18 Mercedes Pelegrín , Liding Xu

We propose a hierarchical architecture for efficiently computing high-quality solutions to structured mixed-integer programs (MIPs). To reduce computational effort, our approach decouples the original problem into a higher level problem and…

Optimization and Control · Mathematics 2025-12-04 Stefan Clarke , Bartolomeo Stellato

Mixed-integer programming (MIP) research is both mathematically sophisticated and engineering-intensive: testing an algorithmic hypothesis within a branch-and-cut solver requires substantial implementation, debugging, tuning, and…

Artificial Intelligence · Computer Science 2026-05-12 Liding Xu , Yugeng Zhou , Sebastian Pokutta

Grid layouts are used by designers to spatially organise user interfaces when sketching and wireframing. However, their design is largely time consuming manual work. This is challenging due to combinatorial explosion and complex objectives,…

Human-Computer Interaction · Computer Science 2020-01-10 Niraj Dayama , Kashyap Todi , Taru Saarelainen , Antti Oulasvirta

Current state-of-the-art solvers for mixed-integer programming (MIP) problems are designed to perform well on a wide range of problems. However, for many real-world use cases, problem instances come from a narrow distribution. This has…

Optimization and Control · Mathematics 2022-02-15 Charly Robinson La Rocca , Emma Frejinger , Jean-François Cordeau

Mixed-integer programming (MIP) is a well-established framework for computer-aided molecular design (CAMD). By precisely encoding the molecular space and score functions, e.g., a graph neural network, the molecular design problem is…

Computational Engineering, Finance, and Science · Computer Science 2024-11-26 Shiqiang Zhang , Christian W. Feldmann , Frederik Sandfort , Miriam Mathea , Juan S. Campos , Ruth Misener

Mixed-Integer Linear Programs (MIPs) are powerful and flexible tools for modeling a wide range of real-world combinatorial optimization problems. Predict-and-Search methods operate by using a predictive model to estimate promising variable…

Artificial Intelligence · Computer Science 2026-04-21 Junyang Cai , El Mehdi Er Raqabi , Pascal Van Hentenryck , Bistra Dilkina

Cutting planes (cuts) play an important role in solving mixed-integer linear programs (MILPs), as they significantly tighten the dual bounds and improve the solving performance. A key problem for cuts is when to stop cuts generation, which…

Artificial Intelligence · Computer Science 2024-02-05 Haotian Ling , Zhihai Wang , Jie Wang

Sequential quadratic programming and sequential convex programming efficiently solve nonlinear programs (NLPs) by linearizing inner nonlinearities while preserving the outer convex structure. This paper introduces a sequential mixed-integer…

Optimization and Control · Mathematics 2026-03-27 Andrea Ghezzi , Wim Van Roy , Sebastian Sager , Moritz Diehl

In this paper, we propose two exact distributed algorithms to solve mixed integer linear programming (MILP) problems with multiple agents where data privacy is important for the agents. A key challenge is that, because of the non-convex…

Optimization and Control · Mathematics 2022-05-03 Mohammad Javad Feizollahi

Mixed-Integer Linear Programming (MILP) is a powerful framework used to address a wide range of NP-hard combinatorial optimization problems, often solved by Branch and Bound (B&B). A key factor influencing the performance of B&B solvers is…

Machine Learning · Computer Science 2025-10-23 Paul Strang , Zacharie Alès , Côme Bissuel , Olivier Juan , Safia Kedad-Sidhoum , Emmanuel Rachelson

We present an ideal mixed-integer programming (MIP) formulation for a rectified linear unit (ReLU) appearing in a trained neural network. Our formulation requires a single binary variable and no additional continuous variables beyond the…

Optimization and Control · Mathematics 2019-03-04 Ross Anderson , Joey Huchette , Christian Tjandraatmadja , Juan Pablo Vielma
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