English
Related papers

Related papers: A Customized Memory-aware Architecture for Biologi…

200 papers

The latest trends in high-performance computing systems show an increasing demand on the use of a large scale multicore systems in a efficient way, so that high compute-intensive applications can be executed reasonably well. However, the…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-02-25 Juliana M. N. Silva , Cristina Boeres , Lúcia M. A. Drummond , Artur A. Pessoa

Spiking neural networks excel at event-driven sensing. Yet, maintaining task-relevant context over long timescales both algorithmically and in hardware, while respecting both tight energy and memory budgets, remains a core challenge in the…

Neural and Evolutionary Computing · Computer Science 2026-05-05 Pengfei Sun , Zhe Su , Jascha Achterberg , Giacomo Indiveri , Dan F. M. Goodman , Danyal Akarca

Genomic data sets are growing dramatically as the cost of sequencing continues to decline and small sequencing devices become available. Enormous community databases store and share this data with the research community, but some of these…

While Moore's law has driven exponential computing power expectations, its nearing end calls for new avenues for improving the overall system performance. One of these avenues is the exploration of alternative brain-inspired computing…

Neural and Evolutionary Computing · Computer Science 2023-05-16 Charlotte Frenkel , David Bol , Giacomo Indiveri

The rapid development of high-throughput sequencing technologies has led to an explosive increase in biological sequence data, making sequence clustering a fundamental task in large-scale bioinformatics analyses. Unlike traditional…

Genomics · Quantitative Biology 2026-01-22 Simeng Zhang , Xinying Liu , Jun Lou , Mudi Jiang , Quan Zou , Zengyou He

The Transformer architecture, underpinned by the self-attention mechanism, has become the de facto standard for sequence modeling tasks. However, its core computational primitive scales quadratically with sequence length (O(N^2)), creating…

Computation and Language · Computer Science 2025-09-03 Rishiraj Acharya

Deep autoregressive sequence-to-sequence models have demonstrated impressive performance across a wide variety of tasks in recent years. While common architecture classes such as recurrent, convolutional, and self-attention networks make…

Machine Learning · Computer Science 2018-11-09 Mitchell Stern , Noam Shazeer , Jakob Uszkoreit

Convolutional Neural Networks (CNNs) have greatly influenced the field of Embedded Vision and Edge Artificial Intelligence (AI), enabling powerful machine learning capabilities on resource-constrained devices. This article explores the…

Computer Vision and Pattern Recognition · Computer Science 2023-11-23 Dwith Chenna

Processing-in-memory (PIM), as a novel computing paradigm, provides significant performance benefits from the aspect of effective data movement reduction. SRAM-based PIM has been demonstrated as one of the most promising candidates due to…

Hardware Architecture · Computer Science 2023-11-01 Cenlin Duan , Jianlei Yang , Xiaolin He , Yingjie Qi , Yikun Wang , Yiou Wang , Ziyan He , Bonan Yan , Xueyan Wang , Xiaotao Jia , Weitao Pan , Weisheng Zhao

Optimal multiple sequence alignment by dynamic programming, like many highly dimensional scientific computing problems, has failed to benefit from the improvements in computing performance brought about by multi-processor systems, due to…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-11-30 Manal Helal , Hossam El-Gindy , Lenore Mullin , Bruno Gaeta

Massively parallel sequencing techniques have revolutionized biological and medical sciences by providing unprecedented insight into the genomes of humans, animals, and microbes. Modern sequencing platforms generate enormous amounts of…

Video analytics pipelines have steadily shifted to edge deployments to reduce bandwidth overheads and privacy violations, but in doing so, face an ever-growing resource tension. Most notably, edge-box GPUs lack the memory needed to…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-05-06 Arthi Padmanabhan , Neil Agarwal , Anand Iyer , Ganesh Ananthanarayanan , Yuanchao Shu , Nikolaos Karianakis , Guoqing Harry Xu , Ravi Netravali

Recent advances demonstrate that irregularly wired neural networks from Neural Architecture Search (NAS) and Random Wiring can not only automate the design of deep neural networks but also emit models that outperform previous manual…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-03-06 Byung Hoon Ahn , Jinwon Lee , Jamie Menjay Lin , Hsin-Pai Cheng , Jilei Hou , Hadi Esmaeilzadeh

We present a work-efficient parallel level-synchronous Breadth First Search (BFS) algorithm for shared-memory architectures which achieves the theoretical lower bound on parallel running time. The optimality holds regardless of the shape of…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-09-20 Jesmin Jahan Tithi , Yonatan Fogel , Rezaul Chowdhury

We present a vision for the Erudite architecture that redefines the compute and memory abstractions such that memory bandwidth and capacity become first-class citizens along with compute throughput. In this architecture, we envision…

Hardware Architecture · Computer Science 2020-08-25 Zaid Qureshi , Vikram Sharma Mailthody , Seung Won Min , I-Hsin Chung , Jinjun Xiong , Wen-mei Hwu

DNA sequencing is revolutionising the field of medicine. DNA sequencers, the machines which perform DNA sequencing, have evolved from the size of a fridge to that of a mobile phone over the last two decades. The cost of sequencing a human…

Genomics · Quantitative Biology 2021-01-14 Hasindu Gamaarachchi

Betweenness centrality is one of the most popular vertex centrality measures in network analysis. Hence, many (sequential and parallel) algorithms to compute or approximate betweenness have been devised. Recent algorithmic advances have…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-10-25 Alexander van der Grinten , Henning Meyerhenke

Large-scale artificial intelligence models are transforming industries and redefining human machine collaboration. However, continued scaling exposes critical limitations in hardware, including constraints on computation, bandwidth, and…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-21 Yuankai Fan , Qizhen Weng , Xuelong Li

DNA sequence alignment is important today as it is usually the first step in finding gene mutation, evolutionary similarities, protein structure, drug development and cancer treatment. Covid-19 is one recent example. There are many…

Genomics · Quantitative Biology 2023-06-01 Suchindra , Preetam Nagaraj

In genomics, pattern matching against a sequence of nucleotides plays a pivotal role for DNA sequence alignment and comparing genomes. This helps tackling some diseases, such as cancer in humans. The complexity of searching biological…

Quantitative Methods · Quantitative Biology 2017-10-04 Fereshte Mozafari , Hossein Babashah , Somayyeh Koohi , Zahra Kavehvash