English
Related papers

Related papers: Hyperbolic Genome Embeddings

200 papers

Artificial neural networks (ANNs) were inspired by the architecture and functions of the human brain and have revolutionised the field of artificial intelligence (AI). Inspired by studies on the latent geometry of the brain, in this…

Neurons and Cognition · Quantitative Biology 2025-02-04 Alexander Joseph , Nathan Francis , Meijke Balay

Learning representations for graphs plays a critical role in a wide spectrum of downstream applications. In this paper, we summarize the limitations of the prior works in three folds: representation space, modeling dynamics and modeling…

Machine Learning · Computer Science 2021-04-07 Li Sun , Zhongbao Zhang , Jiawei Zhang , Feiyang Wang , Hao Peng , Sen Su , Philip S. Yu

Understanding the intricate mappings between visual stimuli and neural responses is a fundamental challenge in cognitive neuroscience. While current approaches predominantly align images and functional magnetic resonance imaging (fMRI)…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Zihan Ma , Tian Xia , Kexin Wang , Xiao Li , Xiaowei He , Yudan Ren

Although self-/un-supervised methods have led to rapid progress in visual representation learning, these methods generally treat objects and scenes using the same lens. In this paper, we focus on learning representations for objects and…

Computer Vision and Pattern Recognition · Computer Science 2022-12-02 Songwei Ge , Shlok Mishra , Simon Kornblith , Chun-Liang Li , David Jacobs

Metagenomic disease prediction commonly relies on species abundance tables derived from large, incomplete reference catalogs, constraining resolution and discarding valuable information contained in DNA reads. To overcome these limitations,…

Genomics · Quantitative Biology 2026-01-08 Gaspar Roy , Eugeni Belda , Baptiste Hennecart , Yann Chevaleyre , Edi Prifti , Jean-Daniel Zucker

Graph-structured data provide a comprehensive description of complex systems, encompassing not only the interactions among nodes but also the intrinsic features that characterize these nodes. These features play a fundamental role in the…

Physics and Society · Physics 2023-11-27 Roya Aliakbarisani , M. Ángeles Serrano , Marián Boguñá

Deep learning has taken part in the competition since not long ago to learn and identify phase transitions in physical systems such as many body quantum systems, whose underlying lattice structures are generally regular as they're in…

Physics and Society · Physics 2020-01-08 Qi Ni , Jie Kang , Ming Tang , Ying Liu , Yong Zou

We develop a geometric framework to study the structure and function of complex networks. We assume that hyperbolic geometry underlies these networks, and we show that with this assumption, heterogeneous degree distributions and strong…

Statistical Mechanics · Physics 2010-09-14 Dmitri Krioukov , Fragkiskos Papadopoulos , Maksim Kitsak , Amin Vahdat , Marian Boguna

Metabolomic data sets provide a direct read-out of cellular phenotypes and are increasingly generated to study biological questions. Our previous work revealed the potential of analyzing extracellular metabolomic data in the context of the…

Molecular Networks · Quantitative Biology 2016-06-10 Maike K. Aurich , Ronan M. T. Fleming , Ines Thiele

Transformer model architectures have become an indispensable staple in deep learning lately for their effectiveness across a range of tasks. Recently, a surge of "X-former" models have been proposed which improve upon the original…

Computation and Language · Computer Science 2021-06-15 Zhe Liu , Yibin Xu

Representation learning is a fundamental building block for analyzing entities in a database. While the existing embedding learning methods are effective in various data mining problems, their applicability is often limited because these…

Machine Learning · Computer Science 2020-09-24 Chin-Chia Michael Yeh , Dhruv Gelda , Zhongfang Zhuang , Yan Zheng , Liang Gou , Wei Zhang

This study proposes a novel approach that combines theory and data-driven choice models using Artificial Neural Networks (ANNs). In particular, we use continuous vector representations, called embeddings, for encoding categorical or…

Machine Learning · Statistics 2021-10-01 Ioanna Arkoudi , Carlos Lima Azevedo , Francisco C. Pereira

Answering complex first-order logic (FOL) queries on knowledge graphs is essential for reasoning. Symbolic methods offer interpretability but struggle with incomplete graphs, while neural approaches generalize better but lack transparency.…

Artificial Intelligence · Computer Science 2026-03-18 Lihui Liu

Many high-dimensional practical data sets have hierarchical structures induced by graphs or time series. Such data sets are hard to process in Euclidean spaces and one often seeks low-dimensional embeddings in other space forms to perform…

Machine Learning · Computer Science 2022-04-13 Chao Pan , Eli Chien , Puoya Tabaghi , Jianhao Peng , Olgica Milenkovic

How can we represent hierarchical information present in large type inventories for entity typing? We study the ability of hyperbolic embeddings to capture hierarchical relations between mentions in context and their target types in a…

Computation and Language · Computer Science 2019-06-07 Federico López , Benjamin Heinzerling , Michael Strube

Similar to natural language models, pre-trained genome language models are proposed to capture the underlying intricacies within genomes with unsupervised sequence modeling. They have become essential tools for researchers and practitioners…

Genomics · Quantitative Biology 2024-06-04 Siyuan Li , Zedong Wang , Zicheng Liu , Di Wu , Cheng Tan , Jiangbin Zheng , Yufei Huang , Stan Z. Li

Hypergraphs are useful mathematical representations of overlapping and nested subsets of interacting units, including groups of genes or brain regions, economic cartels, political or military coalitions, and groups of products that are…

Methodology · Statistics 2026-02-03 Cornelius Fritz , Yubai Yuan , Michael Schweinberger

Growing interest in modelling complex systems from brains to societies to cities using networks has led to increased efforts to describe generative processes that explain those networks. Recent successes in machine learning have prompted…

Neural and Evolutionary Computing · Computer Science 2024-01-12 Govind Gandhi

The length and time scales of atomistic simulations are limited by the computational cost of the methods used to predict material properties. In recent years there has been great progress in the use of machine learning algorithms to develop…

Computational Physics · Physics 2022-11-03 Alberto Hernandez , Adarsh Balasubramanian , Fenglin Yuan , Simon Mason , Tim Mueller

Hyperbolic space naturally encodes hierarchical structures such as phylogenies (binary trees), where inward-bending geodesics reflect paths through least common ancestors, and the exponential growth of neighborhoods mirrors the…

Machine Learning · Computer Science 2025-07-17 Alex Chen , Philipe Chlenski , Kenneth Munyuza , Antonio Khalil Moretti , Christian A. Naesseth , Itsik Pe'er