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Modern single-cell flow and mass cytometry technologies measure the expression of several proteins of the individual cells within a blood or tissue sample. Each profiled biological sample is thus represented by a set of hundreds of…

Machine Learning · Computer Science 2022-06-29 Siyuan Shan , Vishal Baskaran , Haidong Yi , Jolene Ranek , Natalie Stanley , Junier Oliva

Convolutional Neural Networks (CNN) have recently seen tremendous success in various computer vision tasks. However, their application to problems with high dimensional input and output, such as high-resolution image and video segmentation…

Computer Vision and Pattern Recognition · Computer Science 2020-07-09 Keegan Lensink , Bas Peters , Eldad Haber

Electronic Health Records have become popular sources of data for secondary research, but their use is hampered by the amount of effort it takes to overcome the sparsity, irregularity, and noise that they contain. Modern learning…

Applications · Statistics 2025-02-28 Jacek M. Bajor , Diego A. Mesa , Travis J. Osterman , Thomas A. Lasko

Most real-world datasets consist of a natural hierarchy between classes or an inherent label structure that is either already available or can be constructed cheaply. However, most existing representation learning methods ignore this…

Machine Learning · Computer Science 2024-12-03 Aditya Sinha , Siqi Zeng , Makoto Yamada , Han Zhao

Deploying accurate event detection on resource-constrained devices is challenged by the trade-off between performance and computational cost. While Early-Exit (EE) networks offer a solution through adaptive computation, they often fail to…

Knowledge graphs have emerged as fundamental structures for representing complex relational data across scientific and enterprise domains. However, existing embedding methods face critical limitations when modeling diverse relationship…

Artificial Intelligence · Computer Science 2025-11-17 Jugal Gajjar , Kaustik Ranaware , Kamalasankari Subramaniakuppusamy , Vaibhav Gandhi

Neuro-encoded expression programming(NEEP) that aims to offer a novel continuous representation of combinatorial encoding for genetic programming methods is proposed in this paper. Genetic programming with linear representation uses…

Neural and Evolutionary Computing · Computer Science 2021-04-12 Aftab Anjum , Fengyang Sun , Lin Wang , Jeff Orchard

Learning the representation of data with hierarchical structures in the hyperbolic space attracts increasing attention in recent years. Due to the constant negative curvature, the hyperbolic space resembles tree metrics and captures the…

Machine Learning · Computer Science 2022-02-21 Huiru Xiao , Caigao Jiang , Yangqiu Song , James Zhang , Junwu Xiong

The immense increase in the generation of genomic scale data poses an unmet analytical challenge, due to a lack of established methodology with the required flexibility and power. We propose a first principled approach to statistical…

Diffusion generative models (DMs) have achieved promising results in image and graph generation. However, real-world graphs, such as social networks, molecular graphs, and traffic graphs, generally share non-Euclidean topologies and hidden…

Machine Learning · Computer Science 2024-01-04 Lingfeng Wen , Xuan Tang , Mingjie Ouyang , Xiangxiang Shen , Jian Yang , Daxin Zhu , Mingsong Chen , Xian Wei

Obtaining continuous representations of structural data such as directed acyclic graphs (DAGs) has gained attention in machine learning and artificial intelligence. However, embedding complex DAGs in which both ancestors and descendants of…

Machine Learning · Computer Science 2019-05-16 Ryota Suzuki , Ryusuke Takahama , Shun Onoda

Human motion taxonomies serve as high-level hierarchical abstractions that classify how humans move and interact with their environment. They have proven useful to analyse grasps, manipulation skills, and whole-body support poses. Despite…

Since the completion of the human genome sequencing project in 2001, significant progress has been made in areas such as gene regulation editing and protein structure prediction. However, given the vast amount of genomic data, the segments…

Other Quantitative Biology · Quantitative Biology 2025-01-29 Wang Liang

In semi-supervised learning, methods that rely on confidence learning to generate pseudo-labels have been widely proposed. However, increasing research finds that when faced with noisy and biased data, the model's representation network is…

Computer Vision and Pattern Recognition · Computer Science 2024-04-29 Yanbiao Ma , Licheng Jiao , Fang Liu , Lingling Li , Shuyuan Yang , Xu Liu

Recent research in representation learning has shown that hierarchical data lends itself to low-dimensional and highly informative representations in hyperbolic space. However, even if hyperbolic embeddings have gathered attention in image…

Computer Vision and Pattern Recognition · Computer Science 2023-09-20 Gabriel Moreira , Manuel Marques , João Paulo Costeira , Alexander Hauptmann

Representation learning over temporal networks has drawn considerable attention in recent years. Efforts are mainly focused on modeling structural dependencies and temporal evolving regularities in Euclidean space which, however,…

Social and Information Networks · Computer Science 2023-01-31 Menglin Yang , Min Zhou , Marcus Kalander , Zengfeng Huang , Irwin King

Precision oncology requires accurate molecular insights, yet obtaining these directly from genomics is costly and time-consuming for broad clinical use. Predicting complex molecular features and patient prognosis directly from routine…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Cheng Jin , Fengtao Zhou , Yunfang Yu , Jiabo Ma , Yihui Wang , Yingxue Xu , Huajun Zhou , Hao Jiang , Luyang Luo , Luhui Mao , Zifan He , Xiuming Zhang , Jing Zhang , Ronald Chan , Herui Yao , Hao Chen

Proteins perform much of the work in living organisms, and consequently the development of efficient computational methods for protein representation is essential for advancing large-scale biological research. Most current approaches…

Quantitative Methods · Quantitative Biology 2023-06-09 Francesco Ceccarelli , Lorenzo Giusti , Sean B. Holden , Pietro Liò

Hyperbolic neural networks have emerged as a powerful tool for modeling hierarchical data structures prevalent in real-world datasets. Notably, residual connections, which facilitate the direct flow of information across layers, have been…

Machine Learning · Computer Science 2025-01-14 Neil He , Menglin Yang , Rex Ying

Representation learning has become an invaluable approach for learning from symbolic data such as text and graphs. However, while complex symbolic datasets often exhibit a latent hierarchical structure, state-of-the-art methods typically…

Artificial Intelligence · Computer Science 2017-05-29 Maximilian Nickel , Douwe Kiela
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