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Recent advancements in biomedical image analysis have been significantly driven by the Segment Anything Model (SAM). This transformative technology, originally developed for general-purpose computer vision, has found rapid application in…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Ho Hin Lee , Yu Gu , Theodore Zhao , Yanbo Xu , Jianwei Yang , Naoto Usuyama , Cliff Wong , Mu Wei , Bennett A. Landman , Yuankai Huo , Alberto Santamaria-Pang , Hoifung Poon

Breast cancer is one of the most common cancers among women worldwide, with early detection significantly increasing survival rates. Ultrasound imaging is a critical diagnostic tool that aids in early detection by providing real-time…

Image and Video Processing · Electrical Eng. & Systems 2023-05-23 Mingzhe Hu , Yuheng Li , Xiaofeng Yang

Medical image segmentation is a key task in the imaging workflow, influencing many image-based decisions. Traditional, fully-supervised segmentation models rely on large amounts of labeled training data, typically obtained through manual…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Tyler Ward , Meredith K. Owen , O'Kira Coleman , Brian Noehren , Abdullah-Al-Zubaer Imran

Recent advances in vision foundation models, such as the Segment Anything Model (SAM) and its successor SAM2, have achieved state-of-the-art performance on general image segmentation benchmarks. However, these models struggle in adverse…

Computer Vision and Pattern Recognition · Computer Science 2025-09-08 Dharsan Ravindran , Kevin Wang , Zhuoyuan Cao , Saleh Abdelrahman , Jeffery Wu

Background: Tumor segmentation in MRI is crucial in radiotherapy (RT) treatment planning for brain tumor patients. Segment anything (SA), a novel promptable foundation model for autosegmentation, has shown high accuracy for multiple…

The Segment Anything Model (SAM) has garnered significant attention for its versatile segmentation abilities and intuitive prompt-based interface. However, its application in medical imaging presents challenges, requiring either substantial…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Zhiheng Cheng , Qingyue Wei , Hongru Zhu , Yan Wang , Liangqiong Qu , Wei Shao , Yuyin Zhou

Background: We evaluate SAM 2 for surgical scene understanding by examining its semantic segmentation capabilities for organs/tissues both in zero-shot scenarios and after fine-tuning. Methods: We utilized five public datasets to evaluate…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Devanish N. Kamtam , Joseph B. Shrager , Satya Deepya Malla , Xiaohan Wang , Nicole Lin , Juan J. Cardona , Serena Yeung-Levy , Clarence Hu

Surgical video segmentation is critical for AI to interpret spatial-temporal dynamics in surgery, yet model performance is constrained by limited annotated data. The SAM2 model, pretrained on natural videos, offers potential for zero-shot…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Cheng Yuan , Jian Jiang , Kunyi Yang , Lv Wu , Rui Wang , Zi Meng , Haonan Ping , Ziyu Xu , Yifan Zhou , Wanli Song , Hesheng Wang , Yueming Jin , Qi Dou , Yutong Ban

The Segment Anything Model 2 (SAM 2) has emerged as a powerful foundation model for object segmentation in both images and videos, paving the way for various downstream video applications. The crucial design of SAM 2 for video segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Shuangrui Ding , Rui Qian , Xiaoyi Dong , Pan Zhang , Yuhang Zang , Yuhang Cao , Yuwei Guo , Dahua Lin , Jiaqi Wang

The development of machine learning models for CT imaging depends on the availability of large, high-quality, and diverse annotated datasets. Although large volumes of CT images and reports are readily available in clinical picture…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Samuel Church , Joshua D. Warner , Danyal Maqbool , Xin Tie , Junjie Hu , Meghan G. Lubner , Tyler J. Bradshaw

Current AI-assisted skin image diagnosis has achieved dermatologist-level performance in classifying skin cancer, driven by rapid advancements in deep learning architectures. However, unlike traditional vision tasks, skin images in general…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Xin Hu , Janet Wang , Jihun Hamm , Rie R Yotsu , Zhengming Ding

End-to-end medical image segmentation is of great value for computer-aided diagnosis dominated by task-specific models, usually suffering from poor generalization. With recent breakthroughs brought by the segment anything model (SAM) for…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Xian Lin , Yangyang Xiang , Li Yu , Zengqiang Yan

The Segment Anything Model (SAM) is a powerful vision foundation model that is revolutionizing the traditional paradigm of segmentation. Despite this, a reliance on prompting each frame and large computational cost limit its usage in…

Computer Vision and Pattern Recognition · Computer Science 2024-07-03 Zijian Wu , Adam Schmidt , Peter Kazanzides , Septimiu E. Salcudean

Segmentation of anatomical structures and pathological regions in medical images is essential for modern clinical diagnosis, disease research, and treatment planning. While significant advancements have been made in deep learning-based…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Taha Koleilat , Hojat Asgariandehkordi , Hassan Rivaz , Yiming Xiao

The Segment Anything Model 2 (SAM2) demonstrates remarkable universal segmentation capabilities on natural images. However, its performance on ultrasound images is significantly degraded due to domain disparities. This limitation raises two…

Image and Video Processing · Electrical Eng. & Systems 2025-11-21 Yue Li , Qing Xu , Yixuan Zhang , Xiangjian He , Qian Zhang , Yuan Yao , Fiseha B. Tesem , Xin Chen , Ruili Wang , Zhen Chen , Chang Wen Chen

Foundation models like the segment anything model require high-quality manual prompts for medical image segmentation, which is time-consuming and requires expertise. SAM and its variants often fail to segment structures in ultrasound (US)…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Assefa Seyoum Wahd , Banafshe Felfeliyan , Yuyue Zhou , Shrimanti Ghosh , Adam McArthur , Jiechen Zhang , Jacob L. Jaremko , Abhilash Hareendranathan

Segmentation of indicated targets aids in the precise analysis of optical coherence tomography angiography (OCTA) samples. Existing segmentation methods typically perform on 2D projection targets, making it challenging to capture the…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Xinrun Chen , Chengliang Wang , Haojian Ning , Mengzhan Zhang , Mei Shen , Shiying Li

Nuclei instance segmentation is critical in computational pathology for cancer diagnosis and prognosis. Recently, the Segment Anything Model has demonstrated exceptional performance in various segmentation tasks, leveraging its rich priors…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Jingze Su , Tianle Zhu , Jiaxin Cai , Zhiyi Wang , Qi Li , Xiao Zhang , Tong Tong , Shu Wang , Wenxi Liu

The Segment Anything Model (SAM) has exhibited outstanding performance in various image segmentation tasks. Despite being trained with over a billion masks, SAM faces challenges in mask prediction quality in numerous scenarios, especially…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Zhaozhi Xie , Bochen Guan , Weihao Jiang , Muyang Yi , Yue Ding , Hongtao Lu , Lei Zhang

In this study, we evaluate the performance of the Segment Anything Model (SAM) in clinical radiotherapy. Our results indicate that SAM's 'segment anything' mode can achieve clinically acceptable segmentation results in most organs-at-risk…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Lian Zhang , Zhengliang Liu , Lu Zhang , Zihao Wu , Xiaowei Yu , Jason Holmes , Hongying Feng , Haixing Dai , Xiang Li , Quanzheng Li , Dajiang Zhu , Tianming Liu , Wei Liu