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How can we generate samples from a conditional distribution that we never fully observe? This question arises across a broad range of applications in both modern machine learning and classical statistics, including image post-processing in…

Machine Learning · Statistics 2026-05-26 Anirban Chatterjee , Sayantan Choudhury , Rohan Hore

Accurately identifying oocytes that progress to the blastocyst stage is crucial in reproductive medicine, but the limited availability of annotated high-quality embryo images presents challenges for developing automated diagnostic tools. To…

Quantitative Methods · Quantitative Biology 2025-06-18 Alejandro Golfe , Natalia P. García-de-la-puente , Adrián Colomer , Valery Naranjo

Recent deep learning-based image completion methods, including both inpainting and outpainting, have demonstrated promising results in restoring corrupted images by effectively filling various missing regions. Among these, Generative…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Yike Zhang , Eduardo Davalos , Jack Noble

Cone-beam computed tomography (CBCT) is widely used in image-guided radiotherapy. Reconstructing CBCTs from limited-angle acquisitions (LA-CBCT) is highly desired for improved imaging efficiency, dose reduction, and better mechanical…

Medical Physics · Physics 2024-04-10 Jiacheng Xie , Hua-Chieh Shao , Yunxiang Li , You Zhang

Diffusion-based Deep Generative Models (DDGMs) offer state-of-the-art performance in generative modeling. Their main strength comes from their unique setup in which a model (the backward diffusion process) is trained to reverse the forward…

Machine Learning · Computer Science 2022-06-02 Kamil Deja , Anna Kuzina , Tomasz Trzciński , Jakub M. Tomczak

It is widely accepted that medical imaging systems should be objectively assessed via task-based image quality (IQ) measures that ideally account for all sources of randomness in the measured image data, including the variation in the…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Xichen Xu , Wentao Chen , Weimin Zhou

Mammography-based screening has helped reduce the breast cancer mortality rate, but has also been associated with potential harms due to low specificity, leading to unnecessary exams or procedures, and low sensitivity. Digital breast…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Sadanand Singh , Thomas Paul Matthews , Meet Shah , Brent Mombourquette , Trevor Tsue , Aaron Long , Ranya Almohsen , Stefano Pedemonte , Jason Su

Deep generative models have demonstrated remarkable success in medical image synthesis. However, ensuring conditioning faithfulness and high-quality synthetic images for direct or counterfactual generation remains a challenge. In this work,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Fangrui Huang , Alan Wang , Binxu Li , Bailey Trang , Ridvan Yesiloglu , Tianyu Hua , Wei Peng , Ehsan Adeli

Recent advances in computer vision have shown promising results in image generation. Diffusion probabilistic models in particular have generated realistic images from textual input, as demonstrated by DALL-E 2, Imagen and Stable Diffusion.…

The video generation field has witnessed rapid improvements with the introduction of recent diffusion models. While these models have successfully enhanced appearance quality, they still face challenges in generating coherent and natural…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Yaosi Hu , Zhenzhong Chen , Chong Luo

Text-to-image generation models have achieved remarkable capabilities in synthesizing images, but often struggle to provide fine-grained control over the output. Existing guidance approaches, such as segmentation maps and depth maps,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Sangmin Jung , Utkarsh Nath , Yezhou Yang , Giulia Pedrielli , Joydeep Biswas , Amy Zhang , Hassan Ghasemzadeh , Pavan Turaga

Synthesizing fully developed three-dimensional turbulent velocity fields remains a long-standing problem in fluid mechanics and an open challenge for generative modeling. The difficulty arises from the coexistence of extreme dimensionality,…

Fluid Dynamics · Physics 2026-03-16 Tianyi Li , Michele Buzzicotti , Fabio Bonaccorso , Luca Biferale

Medical image segmentation is crucial for clinical diagnosis and treatment planning. Traditional methods typically produce a single segmentation mask, failing to capture inherent uncertainty. Recent generative models enable the creation of…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Huynh Trinh Ngoc , Toan Nguyen Hai , Ba Luong Son , Long Tran Quoc

Multi-modality magnetic resonance imaging (MRI) is essential for the diagnosis and treatment of brain tumors. However, missing modalities are commonly observed due to limitations in scan time, scan corruption, artifacts, motion, and…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Xiaojiao Xiao , Qinmin Vivian Hu , Guanghui Wang

Significant disparities between the features of natural images and those inherent to histopathological images make it challenging to directly apply and transfer pre-trained models from natural images to histopathology tasks. Moreover, the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Zhenfeng Zhuang , Min Cen , Yanfeng Li , Fangyu Zhou , Lequan Yu , Baptiste Magnier , Liansheng Wang

Latent Diffusion models (LDMs) have achieved remarkable results in synthesizing high-resolution images. However, the iterative sampling process is computationally intensive and leads to slow generation. Inspired by Consistency Models (song…

Computer Vision and Pattern Recognition · Computer Science 2023-10-09 Simian Luo , Yiqin Tan , Longbo Huang , Jian Li , Hang Zhao

In this work, we propose a denoising diffusion generative model (DDGM) trained with healthy electrocardiogram (ECG) data that focuses on ECG morphology and inter-lead dependence. Our results show that this innovative generative model can…

Signal Processing · Electrical Eng. & Systems 2024-01-12 Gabriel V. Cardoso , Lisa Bedin , Josselin Duchateau , Rémi Dubois , Eric Moulines

A precise assessment of the risk of breast lesions can greatly lower it and assist physicians in choosing the best course of action. To categorise breast lesions, the majority of current computer-aided systems only use characteristics from…

Image and Video Processing · Electrical Eng. & Systems 2025-08-25 Muhaisin Tiyumba Nantogmah , Abdul-Barik Alhassan , Salamudeen Alhassan

Denoising diffusion models, a class of generative models, have garnered immense interest lately in various deep-learning problems. A diffusion probabilistic model defines a forward diffusion stage where the input data is gradually perturbed…

Image and Video Processing · Electrical Eng. & Systems 2023-06-06 Amirhossein Kazerouni , Ehsan Khodapanah Aghdam , Moein Heidari , Reza Azad , Mohsen Fayyaz , Ilker Hacihaliloglu , Dorit Merhof

Contemporary glioma diagnosis integrates molecular features with histopathology to guide clinical decision-making. However, in clinical settings, divergent imaging protocols result in incomplete MRI sequences, leading to two primary…

Image and Video Processing · Electrical Eng. & Systems 2026-05-25 Pengfei Song , Fangjin Liu , Wenwen Zeng , Yonghuang Wu , Chengqian Zhao , Feiyu Yin , Xuan Xie , Jinhua Yu