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Image-based patient-specific simulation of left ventricular (LV) mechanics is valuable for understanding cardiac function and supporting clinical intervention planning, but conventional finite-element analysis (FEA) is computationally…
Background: Cardiac MRI derived biventricular mass and function parameters, such as end-systolic volume (ESV), end-diastolic volume (EDV), ejection fraction (EF), stroke volume (SV), and ventricular mass (VM) are clinically well…
In the United States, heart disease is the leading cause of death for both men and women, accounting for 610,000 deaths each year [1]. Physicians use Magnetic Resonance Imaging (MRI) scans to take images of the heart in order to…
Segmentation of cardiac structures is one of the fundamental steps to estimate volumetric indices of the heart. This step is still performed semi-automatically in clinical routine, and is thus prone to inter- and intra-observer variability.…
Automated construction of surface geometries of cardiac structures from volumetric medical images is important for a number of clinical applications. While deep-learning-based approaches have demonstrated promising reconstruction precision,…
Segmentation of the Left ventricle (LV) is a crucial step for quantitative measurements such as area, volume, and ejection fraction. However, the automatic LV segmentation in 2D echocardiographic images is a challenging task due to…
Finite element analysis (FEA) forms the cornerstone of modeling cardiac biomechanics but is computationally expensive, limiting its clinical application for digital twin creation, which often requires tens to hundreds of simulations to…
In the field of heart disease classification, two primary obstacles arise. Firstly, existing Electrocardiogram (ECG) datasets consistently demonstrate imbalances and biases across various modalities. Secondly, these time-series data consist…
The prediction of heart surface potentials using measurements from the body's surface is known as the inverse problem of electrocardiography. It is an ill-posed problem due to the multiple factors that affect the heart signal as it…
Electrocardiograms (ECGs) provide non-invasive measurements of heart activity and are established tools for detecting cardiac arrhythmias. Although supervised machine learning has emerged as a promising approach for automated heartbeat…
Healthcare is one of the most important aspects of human life. Heart disease is known to be one of the deadliest diseases which is hampering the lives of many people around the world. Heart disease must be detected early so the loss of…
Fully automatic cardiac segmentation can be a fast and reproducible method to extract clinical measurements from an echocardiography examination. The U-Net architecture is the current state-of-the-art deep learning architecture for medical…
Cardiac left ventricle (LV) quantification is among the most clinically important tasks for identification and diagnosis of cardiac diseases, yet still a challenge due to the high variability of cardiac structure and the complexity of…
Left ventricular ejection fraction (LVEF) is a key indicator of cardiac function and plays a central role in the diagnosis and management of cardiovascular disease. Echocardiography, as a readily accessible and non-invasive imaging…
Electrocardiogram (ECG) detection and delineation are key steps for numerous tasks in clinical practice, as ECG is the most performed non-invasive test for assessing cardiac condition. State-of-the-art algorithms employ digital signal…
An electrocardiogram (ECG) monitors the electrical activity generated by the heart and is used to detect fatal cardiovascular diseases (CVDs). Conventionally, to capture the precise electrical activity, clinical experts use multiple-lead…
Coronary artery disease, caused by the narrowing of coronary vessels due to atherosclerosis, is the leading cause of death worldwide. The diagnostic gold standard, fractional flow reserve (FFR), measures the trans-stenotic pressure ratio…
Image-based computational models of the heart represent a powerful tool to shed new light on the mechanisms underlying physiological and pathological conditions in cardiac function and to improve diagnosis and therapy planning. However, in…
Solving inverse problems in cardiac electrophysiology consists in the recovery of physiological parameters from surface electrocardiogram (ECG) measurements, a task which is often computationally unfeasible due to the severe ill-posedness…
MOTIVATION: Left ventricular (LV) hypertrophy is a strong predictor of cardiovascular outcomes, but its genetic regulation remains largely unexplained. Conventional phenotyping relies on manual calculation of LV mass and wall thickness, but…