Related papers: Open problems in ageing science: A roadmap for bio…
In the last ten years, the field of proteomics has expanded at a rapid rate. A range of exciting new technology has been developed and enthusiastically applied to an enormous variety of biological questions. However, the degree of…
Animal vocalisations and natural soundscapes are fascinating objects of study, and contain valuable evidence about animal behaviours, populations and ecosystems. They are studied in bioacoustics and ecoacoustics, with signal processing and…
Diverse subfields of neuroscience have enriched artificial intelligence for many decades. With recent advances in machine learning and artificial neural networks, many neuroscientists are partnering with AI researchers and machine learning…
Throughout the evolution of biological species on Earth, cells and organs have developed many complex structures and processes to ensure their interactions with individual chemical molecules (small and macromolecular) and nanoscale objects…
The roadmap is organized into several thematic sections, outlining current computing challenges, discussing the neuromorphic computing approach, analyzing mature and currently utilized technologies, providing an overview of emerging…
Biological systems are influenced by fluid mechanics at nearly all spatiotemporal scales. This broad relevance of fluid mechanics to biology has been increasingly appreciated by engineers and biologists alike, leading to continued expansion…
The complexity of human biology and its intricate systems holds immense potential for advancing human health, disease treatment, and scientific discovery. However, traditional manual methods for studying biological interactions are often…
This report is a serious call to scientists, innovators, investors, and policymakers to invest in the development of biophysics in Africa. The complex problems of our day demand multidisciplinary approaches, and biophysics offers training…
The development of artificial intelligence (AI) has made various industries eager to explore the benefits of AI. There is an increasing amount of research surrounding AI, most of which is centred on the development of new AI algorithms and…
An introductory guide to mathematical cosmology is given focusing on the issue of the genericity of various important results which have been obtained during the last thirty or so years. Some of the unsolved problems along with certain new…
With the completion of human genome mapping, the focus of scientists seeking to explain the biological complexity of living systems is shifting from analyzing the individual components (such as a particular gene or biochemical reaction) to…
Biomedical research yields a wealth of information, much of which is only accessible through the literature. Consequently, literature search is an essential tool for building on prior knowledge in clinical and biomedical research. Although…
The origin and early evolution of eukaryotes are one of the major transitions in the evolution of life on earth. One of its most interesting aspects is the emergence of cellular organelles, their dynamics, their functions, and their…
Advances in healthcare and in the quality of life significantly increase human life expectancy. With the ageing of populations, new un-faced challenges are brought to science. The human body is naturally selected to be well-functioning…
Understanding how genotypes map onto phenotypes, fitness, and eventually organisms is arguably the next major missing piece in a fully predictive theory of evolution. We refer to this generally as the problem of the genotype-phenotype map.…
The need for reliably determining the identity of a person is critical in a number of different domains ranging from personal smartphones to border security; from autonomous vehicles to e-voting; from tracking child vaccinations to…
Generative AI models, including large language models and multimodal models that include text and other media, are on the cusp of transforming many aspects of modern life, including entertainment, education, civic life, the arts, and a…
All human diseases involve proteins, yet our current tools to characterize and quantify them are limited. To better elucidate proteins across space, time, and molecular composition, we provide provocative projections for technologies to…
Aging is a fundamental aspect of living systems that undergo a progressive deterioration of physiological function with age and an increase of vulnerability to disease and death. Living systems, known as complex systems, require complexity…
Biostasis has the potential to extend human lives by offering a bridge to powerful life extension technologies that may be developed in the future. However, key questions in the field remain unresolved, including which biomarkers reliably…