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Glioblastoma (GBM) is a highly aggressive primary brain tumor with limited therapeutic options and poor prognosis. The methylation status of the O6-methylguanine-DNA methyltransferase (MGMT) gene promoter is a critical molecular biomarker…

Machine Learning · Computer Science 2026-01-13 Hasan M Jamil

Medulloblastoma (MB) is the most common malignant brain tumor in childhood. The diagnosis is generally based on the microscopic evaluation of histopathological tissue slides. However, visual-only assessment of histopathological patterns is…

Image and Video Processing · Electrical Eng. & Systems 2021-09-14 Marcel Bengs , Michael Bockmayr , Ulrich Schüller , Alexander Schlaefer

Accurate and reliable brain tumor segmentation is a critical component in cancer diagnosis, treatment planning, and treatment outcome evaluation. Build upon successful deep learning techniques, a novel brain tumor segmentation method is…

Computer Vision and Pattern Recognition · Computer Science 2017-11-13 Xiaomei Zhao , Yihong Wu , Guidong Song , Zhenye Li , Yazhuo Zhang , Yong Fan

Deep learning methods for brain tumor segmentation are typically trained in an ad hoc fashion on all available data. Brain tumors are tremendously heterogeneous in image appearance and labeled training data is limited. We argue that…

Image and Video Processing · Electrical Eng. & Systems 2019-07-31 Raphael Meier , Michael Rebsamen , Urspeter Knecht , Mauricio Reyes , Roland Wiest , Richard McKinley

Surgery for brain cancer is a major problem in neurosurgery. The diffuse infiltration into the surrounding normal brain by these tumors makes their accurate identification by the naked eye difficult. Since surgery is the common treatment…

Glioblastoma is one of the most aggressive and deadliest types of brain cancer, with low survival rates compared to other types of cancer. Analysis of Magnetic Resonance Imaging (MRI) scans is one of the most effective methods for the…

Image and Video Processing · Electrical Eng. & Systems 2023-12-20 Huafeng Liu , Benjamin Dowdell , Todd Engelder , Zarah Pulmano , Nicolas Osa , Arko Barman

Tumor segmentation from multi-modal brain MRI images is a challenging task due to the limited samples, high variance in shapes and uneven distribution of tumor morphology. The performance of automated medical image segmentation has been…

Image and Video Processing · Electrical Eng. & Systems 2024-02-13 Tianyi Ren , Ethan Honey , Harshitha Rebala , Abhishek Sharma , Agamdeep Chopra , Mehmet Kurt

Accurate segmentation of brain tumors from 3D multimodal MRI is vital for diagnosis and treatment planning across diverse brain tumors. This paper addresses the challenges posed by the BraTS 2023, presenting a unified transfer learning…

Image and Video Processing · Electrical Eng. & Systems 2024-12-12 Ramy A. Zeineldin , Franziska Mathis-Ullrich

Segmentation is crucial for brain gliomas as it delineates the glioma s extent and location, aiding in precise treatment planning and monitoring, thus improving patient outcomes. Accurate segmentation ensures proper identification of the…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Kiranmayee Janardhan , Vinay Martin DSa Prabhu , T. Christy Bobby

Brain tumor segmentation plays an essential role in medical image analysis. In recent studies, deep convolution neural networks (DCNNs) are extremely powerful to tackle tumor segmentation tasks. We propose in this paper a novel training…

Image and Video Processing · Electrical Eng. & Systems 2020-10-29 Hieu T. Nguyen , Tung T. Le , Thang V. Nguyen , Nhan T. Nguyen

Brain Tumor Segmentation (BraTS) plays a critical role in clinical diagnosis, treatment planning, and monitoring the progression of brain tumors. However, due to the variability in tumor appearance, size, and intensity across different MRI…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 Hongjun Zhu , Jiaohang Huang , Kuo Chen , Xuehui Ying , Ying Qian

Motivation: Accurate classification of mitotic figures into normal and atypical types is crucial for tumor prognostication in digital pathology. However, developing robust deep learning models for this task is challenging due to the subtle…

Image and Video Processing · Electrical Eng. & Systems 2025-09-16 Sujatha Kotte , Vangala Govindakrishnan Saipradeep , Vidushi Walia , Dhandapani Nandagopal , Thomas Joseph , Naveen Sivadasan , Bhagat Singh Lali

Accurate characterization of glioma is crucial for clinical decision making. A delineation of the tumor is also desirable in the initial decision stages but is a time-consuming task. Leveraging the latest GPU capabilities, we developed a…

Precise prognostic modeling of glioblastoma (GBM) under varying treatment interventions is essential for optimizing clinical outcomes. While generative AI has shown promise in simulating GBM evolution, existing methods typically treat…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Chenhui Wang , Boyun Zheng , Liuxin Bao , Zhihao Peng , Peter Y. M. Woo , Hongming Shan , Yixuan Yuan

The paper demonstrates the use of the fully convolutional neural network for glioma segmentation on the BraTS 2019 dataset. Three-layers deep encoder-decoder architecture is used along with dense connection at encoder part to propagate the…

Image and Video Processing · Electrical Eng. & Systems 2019-09-23 Rupal Agravat , Mehul S Raval

Segmentation is a crucial task in the medical imaging field and is often an important primary step or even a prerequisite to the analysis of medical volumes. Yet treatments such as surgery complicate the accurate delineation of regions of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-13 Heejong Kim , Leo Milecki , Mina C Moghadam , Fengbei Liu , Minh Nguyen , Eric Qiu , Abhishek Thanki , Mert R Sabuncu

Glioblastoma multiforme (GBM) is a fast-growing and highly invasive brain tumour, it tends to occur in adults between the ages of 45 and 70 and it accounts for 52 percent of all primary brain tumours. Usually, GBMs are detected by magnetic…

Image and Video Processing · Electrical Eng. & Systems 2020-04-21 Matteo Rucco , Lorenzo Falsetti , Giovanna Viticchi

Deep learning methods are actively used for brain lesion segmentation. One of the most popular models is DeepMedic, which was developed for segmentation of relatively large lesions like glioma and ischemic stroke. In our work, we consider…

Computer Vision and Pattern Recognition · Computer Science 2018-08-02 Egor Krivov , Valery Kostjuchenko , Alexandra Dalechina , Boris Shirokikh , Gleb karchuk , Alexander Denisenko , Andrey Golanov , Mikhail Belyaev

Glioma, a prevalent and heterogeneous tumor originating from the glial cells, can be differentiated as Low Grade Glioma (LGG) and High Grade Glioma (HGG) according to World Health Organization's norms. Classifying gliomas is essential for…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Kiranmayee Janardhan , Christy Bobby Thomas

Precise breast cancer classification on histopathological images has the potential to greatly improve the diagnosis and patient outcome in oncology. The data imbalance problem largely stems from the inherent imbalance within medical image…

Image and Video Processing · Electrical Eng. & Systems 2024-11-28 Majid Behzadpour , Bengie L. Ortiz , Ebrahim Azizi , Kai Wu