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Glioma constitutes 80% of malignant primary brain tumors and is usually classified as HGG and LGG. The LGG tumors are less aggressive, with slower growth rate as compared to HGG, and are responsive to therapy. Tumor biopsy being challenging…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Subhashis Banerjee , Sushmita Mitra , Francesco Masulli , Stefano Rovetta

Mathematical oncology provides unique and invaluable insights into tumour growth on both the microscopic and macroscopic levels. This review presents state-of-the-art modelling techniques and focuses on their role in understanding…

Background Brain tumours are the most common solid malignancies in children, encompassing diverse histological, molecular subtypes and imaging features and outcomes. Paediatric brain tumours (PBTs), including high- and low-grade gliomas…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 A. Piffer , J. A. Buchner , A. G. Gennari , P. Grehten , S. Sirin , E. Ross , I. Ezhov , M. Rosier , J. C. Peeken , M. Piraud , B. Menze , A. Guerreiro Stücklin , A. Jakab , F. Kofler

Survival prediction models can potentially be used to guide treatment of glioblastoma patients. However, currently available MR imaging biomarkers holding prognostic information are often challenging to interpret, have difficulties…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Sveinn Pálsson , Stefano Cerri , Hans Skovgaard Poulsen , Thomas Urup , Ian Law , Koen Van Leemput

Patient-derived cells (PDC) mouse xenografts are increasingly important tools in glioblastoma (GBM) research, essential to investigate case-specific growth patterns and treatment responses. Despite the central role of xenograft models in…

Quantitative Methods · Quantitative Biology 2024-03-15 Adam A. Malik , Cecilia Krona , Soumi Kundu , Philip Gerlee , Sven Nelander

Cancer histology reveals disease progression and associated molecular processes, and contains rich phenotypic information that is predictive of outcome. In this paper, we developed a computational approach based on deep learning to predict…

Image and Video Processing · Electrical Eng. & Systems 2019-09-20 Saima Rathore , Muhammad Aksam Iftikhar , Zissimos Mourelatos

Integrating cross-department multi-modal data (e.g., radiological, pathological, genomic, and clinical data) is ubiquitous in brain cancer diagnosis and survival prediction. To date, such an integration is typically conducted by human…

Machine Learning · Computer Science 2022-07-20 Can Cui , Han Liu , Quan Liu , Ruining Deng , Zuhayr Asad , Yaohong WangShilin Zhao , Haichun Yang , Bennett A. Landman , Yuankai Huo

Glioblastomas are the most common malignant brain tumors in adults. Approximately 200000 people die each year from Glioblastoma in the world. Glioblastoma patients have a median survival of 12 months with optimal therapy and about 4 months…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Vikram Goddla

Cancer of the brain is deadly and requires careful surgical segmentation. The brain tumors were segmented using U-Net using a Convolutional Neural Network (CNN). When looking for overlaps of necrotic, edematous, growing, and healthy tissue,…

Image and Video Processing · Electrical Eng. & Systems 2023-01-18 MD Abdullah Al Nasim , Abdullah Al Munem , Maksuda Islam , Md Aminul Haque Palash , MD. Mahim Anjum Haque , Faisal Muhammad Shah

Accurate brain tumor classification is crucial in medical imaging to ensure reliable diagnosis and effective treatment planning. This study introduces a novel double ensembling framework that synergistically combines pre-trained deep…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Zahid Ullah , Jihie Kim

The presence of MGMT promoter methylation significantly affects how well chemotherapy works for patients with Glioblastoma Multiforme (GBM). Currently, confirmation of MGMT promoter methylation relies on invasive brain tumor tissue…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Rawan Alyahya , Asrar Alruwayqi , Atheer Alqarni , Asma Alkhaldi , Metab Alkubeyyer , Xin Gao , Mona Alshahrani

Accurate segmentation of brain metastases (BMs) in MR image is crucial for the diagnosis and follow-up of patients. Methods based on deep convolutional neural networks (CNNs) have achieved high segmentation performance. However, due to the…

Image and Video Processing · Electrical Eng. & Systems 2024-10-30 Zijiang Liu , Xiaoyu Liu , Linhao Qu , Yonghong Shi

In the past ten years, with the help of deep learning, especially the rapid development of deep neural networks, medical image analysis has made remarkable progress. However, how to effectively use the relational information between various…

Computer Vision and Pattern Recognition · Computer Science 2023-03-29 Zhihua Liu

In this paper, we present a fully automatic brain tumor segmentation and classification model using a Deep Convolutional Neural Network that includes a multiscale approach. One of the differences of our proposal with respect to previous…

Image and Video Processing · Electrical Eng. & Systems 2024-02-12 Francisco Javier Díaz-Pernas , Mario Martínez-Zarzuela , Míriam Antón-Rodríguez , David González-Ortega

Breast cancer has the highest incidence and second highest mortality rate for women in the US. Our study aims to utilize deep learning for benign/malignant classification of mammogram tumors using a subset of cases from the Digital Database…

Computer Vision and Pattern Recognition · Computer Science 2017-05-19 Darvin Yi , Rebecca Lynn Sawyer , David Cohn , Jared Dunnmon , Carson Lam , Xuerong Xiao , Daniel Rubin

Pediatric central nervous system tumors are the leading cause of cancer-related deaths in children. The five-year survival rate for high-grade glioma in children is less than 20%. The development of new treatments is dependent upon…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Anahita Fathi Kazerooni , Nastaran Khalili , Xinyang Liu , Debanjan Haldar , Zhifan Jiang , Anna Zapaishchykova , Julija Pavaine , Lubdha M. Shah , Blaise V. Jones , Nakul Sheth , Sanjay P. Prabhu , Aaron S. McAllister , Wenxin Tu , Khanak K. Nandolia , Andres F. Rodriguez , Ibraheem Salman Shaikh , Mariana Sanchez Montano , Hollie Anne Lai , Maruf Adewole , Jake Albrecht , Udunna Anazodo , Hannah Anderson , Syed Muhammed Anwar , Alejandro Aristizabal , Sina Bagheri , Ujjwal Baid , Timothy Bergquist , Austin J. Borja , Evan Calabrese , Verena Chung , Gian-Marco Conte , James Eddy , Ivan Ezhov , Ariana M. Familiar , Keyvan Farahani , Deep Gandhi , Anurag Gottipati , Shuvanjan Haldar , Juan Eugenio Iglesias , Anastasia Janas , Elaine Elaine , Alexandros Karargyris , Hasan Kassem , Neda Khalili , Florian Kofler , Dominic LaBella , Koen Van Leemput , Hongwei B. Li , Nazanin Maleki , Zeke Meier , Bjoern Menze , Ahmed W. Moawad , Sarthak Pati , Marie Piraud , Tina Poussaint , Zachary J. Reitman , Jeffrey D. Rudie , Rachit Saluja , MIcah Sheller , Russell Takeshi Shinohara , Karthik Viswanathan , Chunhao Wang , Benedikt Wiestler , Walter F. Wiggins , Christos Davatzikos , Phillip B. Storm , Miriam Bornhorst , Roger Packer , Trent Hummel , Peter de Blank , Lindsey Hoffman , Mariam Aboian , Ali Nabavizadeh , Jeffrey B. Ware , Benjamin H. Kann , Brian Rood , Adam Resnick , Spyridon Bakas , Arastoo Vossough , Marius George Linguraru

Brain tumors are abnormal cell growths in the central nervous system (CNS), and their timely detection is critical for improving patient outcomes. This paper proposes an automatic and efficient deep-learning framework for brain tumor…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Ahta-Shamul Hoque Emran , Hafija Akter , Abdullah Al Shiam , Abu Saleh Musa Miah , Anichur Rahman , Fahmid Al Farid , Hezerul Abdul Karim

The ability to estimate how a tumor might evolve in the future could have tremendous clinical benefits, from improved treatment decisions to better dose distribution in radiation therapy. Recent work has approached the glioma growth…

Tumour heterogeneity in breast cancer poses challenges in predicting outcome and response to therapy. Spatial transcriptomics technologies may address these challenges, as they provide a wealth of information about gene expression at the…

Image and Video Processing · Electrical Eng. & Systems 2023-09-19 Md Mamunur Rahaman , Ewan K. A. Millar , Erik Meijering

Gliomas are the most frequent primary brain tumors in adults. Glioma change detection aims at finding the relevant parts of the image that change over time. Although Deep Learning (DL) shows promising performances in similar change…

Computer Vision and Pattern Recognition · Computer Science 2023-01-27 Tommaso Di Noto , Meritxell Bach Cuadra , Chirine Atat , Eduardo Gamito Teiga , Monika Hegi , Andreas Hottinger , Patric Hagmann , Jonas Richiardi
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