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The pharmaceutical industry faces unprecedented challenges in drug discovery, with traditional approaches struggling to meet modern therapeutic development demands. This paper introduces a novel AI framework, Tippy, that transforms…

Artificial intelligence (AI) agents are emerging as transformative tools in drug discovery, with the ability to autonomously reason, act, and learn through complicated research workflows. Building on large language models (LLMs) coupled…

This technical brief introduces Deep Agent, an advanced autonomous AI system designed to manage complex multi-phase tasks through a novel hierarchical task management architecture. The system's foundation is built on our Hierarchical Task…

Artificial Intelligence · Computer Science 2025-02-12 Amy Yu , Erik Lebedev , Lincoln Everett , Xiaoxin Chen , Terry Chen

Artificial intelligence systems for scientific discovery have demonstrated remarkable potential, yet existing approaches remain largely proprietary and operate in batch-processing modes requiring hours per research cycle, precluding…

Artificial Intelligence · Computer Science 2026-01-28 Lukas Weidener , Marko Brkić , Mihailo Jovanović , Ritvik Singh , Chiara Baccin , Emre Ulgac , Alex Dobrin , Aakaash Meduri

Modern analytics systems are fundamentally reactive, requiring users to define queries over increasingly complex and continuously evolving data. In real-time streaming environments, this paradigm breaks down, as the space of potential…

Artificial Intelligence · Computer Science 2026-05-28 Gaetano Rossiello , Dharmashankar Subramanian

This paper introduces a multi-agent application system designed to enhance office collaboration efficiency and work quality. The system integrates artificial intelligence, machine learning, and natural language processing technologies,…

Artificial Intelligence · Computer Science 2025-04-08 Songtao Sun , Jingyi Li , Yuanfei Dong , Haoguang Liu , Chenxin Xu , Fuyang Li , Qiang Liu

We introduce tulip agent, an architecture for autonomous LLM-based agents with Create, Read, Update, and Delete access to a tool library containing a potentially large number of tools. In contrast to state-of-the-art implementations, tulip…

Artificial Intelligence · Computer Science 2024-08-01 Felix Ocker , Daniel Tanneberg , Julian Eggert , Michael Gienger

The Agent Directory Service (ADS) is a distributed directory for the discovery of AI agent capabilities, metadata, and provenance. It leverages content-addressed storage, hierarchical taxonomies, and cryptographic signing to enable…

Artificial Intelligence · Computer Science 2025-09-24 Luca Muscariello , Vijoy Pandey , Ramiz Polic

Multi-agent systems increasingly expose explicit workflow structure: agents, tools, tool-access rules, restrictions, and delegation paths. Existing evaluations rely largely on end-to-end task success, benchmark scores, final-response…

Software Engineering · Computer Science 2026-05-27 Nafiseh Kahani , Mojtaba Bagherzadeh

As AI agents evolve, the community is rapidly shifting from single Large Language Models (LLMs) to Multi-Agent Systems (MAS) to overcome cognitive bottlenecks in automated research. However, the optimal multi-agent coordination framework…

Multiagent Systems · Computer Science 2026-05-12 Yang Shen , Zhenyi Yi , Ziyi Zhao , Lijun Sun , Dongyang Li , Chin-Teng Lin , Yuhui Shi

Autonomous AI agents powered by large language models are being deployed in production with capabilities including shell execution, file system access, database queries, and multi-party communication. Recent red teaming research…

Cryptography and Security · Computer Science 2026-03-19 Saikat Maiti

Orchestrated multi-agent systems represent the next stage in the evolution of artificial intelligence, where autonomous agents collaborate through structured coordination and communication to achieve complex, shared objectives. This paper…

Multiagent Systems · Computer Science 2026-01-21 Apoorva Adimulam , Rajesh Gupta , Sumit Kumar

Modern distributed software systems often operate in dynamic environments in which operation conditions change continuously and subsystems may come and go at will, e.g. intelligent traffic management and multi-robot systems. To manage these…

Multiagent Systems · Computer Science 2019-09-10 Danny Weyns , Flavio Oquendo

Fully automated self-driving laboratories are promising to enable high-throughput and large-scale scientific discovery by reducing repetitive labour. However, effective automation requires deep integration of laboratory knowledge, which is…

Artificial Intelligence · Computer Science 2025-09-30 Shuxiang Cao , Zijian Zhang , Mohammed Alghadeer , Simone D Fasciati , Michele Piscitelli , Mustafa Bakr , Peter Leek , Alán Aspuru-Guzik

Modern AI technologies for drug discovery are distributed across heterogeneous platforms-including web applications, desktop environments, and code libraries-leading to fragmented workflows, inconsistent interfaces, and high integration…

Multi-agent systems face a fundamental architectural flaw: agent identity is bound to network location. When agents migrate between providers, scale across instances, or federate across organizations, URI-based identity schemes break…

Multiagent Systems · Computer Science 2026-01-22 Roland R. Rodriguez

Current AI agent frameworks commit early to a single interaction protocol, a fixed tool integration strategy, and static user models, limiting their deployment across diverse interaction paradigms. To address these constraints, we introduce…

Artificial Intelligence · Computer Science 2026-03-25 Alfred Shen , Aaron Shen

Multi-agent systems represent a significant advancement in artificial intelligence, enabling complex problem-solving through coordinated specialized agents. However, these systems face fundamental challenges in context management,…

Multiagent Systems · Computer Science 2025-05-01 Naveen Krishnan

Trilogy is a collaborative project whose key aim is the development of an integrated virtual laboratory to support research training within each institution and collaborative projects between the partners. In this paper, the architecture…

Digital Libraries · Computer Science 2007-05-23 Franck Chevalier , David Harle , Geoffrey Smith

In the rapidly evolving field of artificial intelligence, the ability to harness and integrate knowledge across various domains stands as a paramount challenge and opportunity. This study introduces a novel approach to cross-domain…

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