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The Segment Anything Model (SAM) is a powerful foundation model that introduced revolutionary advancements in natural image segmentation. However, its performance remains sub-optimal when delineating the intricate structure of biomedical…

Image and Video Processing · Electrical Eng. & Systems 2023-10-05 Xiangru Li , Yifei Zhang , Liang Zhao

The Segment Anything Model (SAM) marks a significant advancement in segmentation models, offering robust zero-shot abilities and dynamic prompting. However, existing medical SAMs are not suitable for the multi-scale nature of whole-slide…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Hong Liu , Haosen Yang , Paul J. van Diest , Josien P. W. Pluim , Mitko Veta

The Segment Anything Model (SAM) is a foundation model for general image segmentation. Although it exhibits impressive performance predominantly on natural images, understanding its robustness against various image perturbations and domains…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Yuqing Wang , Yun Zhao , Linda Petzold

The recent Segment Anything Model (SAM) represents a significant breakthrough in scaling segmentation models, delivering strong performance across various downstream applications in the RGB modality. However, directly applying SAM to…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Chenyang Zhu , Bin Xiao , Lin Shi , Shoukun Xu , Xu Zheng

Studying the growth and metabolism of microbes provides critical insights into their evolutionary adaptations to harsh environments, which are essential for microbial research and biotechnology applications. In this study, we developed an…

Image and Video Processing · Electrical Eng. & Systems 2025-05-06 Shuang Zhang , Carleton Coffin , Karyn L. Rogers , Catherine Ann Royer , Ge Wang

Due to the cross-domain distribution shift aroused from diverse medical imaging systems, many deep learning segmentation methods fail to perform well on unseen data, which limits their real-world applicability. Recent works have shown the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-06 Shangqi Gao , Hangqi Zhou , Yibo Gao , Xiahai Zhuang

Recent trends in cell segmentation have shifted towards universal models to handle diverse cell morphologies and imaging modalities. However, for continuously emerging cell types and imaging techniques, these models still require hundreds…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Peilin Zhou , Bo Du , Yongchao Xu

The Segment Anything Model (SAM), a foundational model designed for promptable segmentation tasks, demonstrates exceptional generalization capabilities, making it highly promising for natural scene image segmentation. However, SAM's lack of…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Linghao Zheng , Xinyang Pu , Feng Xu

The Segment Anything Model (SAM) is a deep neural network foundational model designed to perform instance segmentation which has gained significant popularity given its zero-shot segmentation ability. SAM operates by generating masks based…

Computer Vision and Pattern Recognition · Computer Science 2024-04-19 Yona Falinie A. Gaus , Neelanjan Bhowmik , Brian K. S. Isaac-Medina , Toby P. Breckon

The Segment Anything Model (SAM) has demonstrated strong performance in image segmentation of natural scene images. However, its effectiveness diminishes markedly when applied to specific scientific domains, such as Scanning Probe…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Yao Shen , Ziwei Wei , Chunmeng Liu , Shuming Wei , Qi Zhao , Kaiyang Zeng , Guangyao Li

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

Automatic segmentation of medical images is crucial in modern clinical workflows. The Segment Anything Model (SAM) has emerged as a versatile tool for image segmentation without specific domain training, but it requires human prompts and…

Computer Vision and Pattern Recognition · Computer Science 2024-05-16 Yunxiang Li , Bowen Jing , Zihan Li , Jing Wang , You Zhang

Few-shot segmentation has garnered significant attention. Many recent approaches attempt to introduce the Segment Anything Model (SAM) to handle this task. With the strong generalization ability and rich object-specific extraction ability…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Jin Wang , Bingfeng Zhang , Jian Pang , Weifeng Liu , Baodi Liu , Honglong Chen

Amodal instance segmentation, which aims to detect and segment both visible and invisible parts of objects in images, plays a crucial role in various applications including autonomous driving, robotic manipulation, and scene understanding.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Wei-En Tai , Yu-Lin Shih , Cheng Sun , Yu-Chiang Frank Wang , Hwann-Tzong Chen

Federated Learning (FL) enables collaborative model training across decentralized edge devices while preserving data privacy. However, statistical heterogeneity among clients, often manifested as non-IID label distributions, poses…

Machine Learning · Computer Science 2026-01-06 Sameer Rahil , Zain Abdullah Ahmad , Talha Asif

The alignment of serial-section electron microscopy (ssEM) images is critical for efforts in neuroscience that seek to reconstruct neuronal circuits. However, each ssEM plane contains densely packed structures that vary from one section to…

Computer Vision and Pattern Recognition · Computer Science 2017-12-06 Inwan Yoo , David G. C. Hildebrand , Willie F. Tobin , Wei-Chung Allen Lee , Won-Ki Jeong

Magnetic resonance (MR) protocols rely on several sequences to assess pathology and organ status properly. Despite advances in image analysis, we tend to treat each sequence, here termed modality, in isolation. Taking advantage of the…

Computer Vision and Pattern Recognition · Computer Science 2020-11-11 Agisilaos Chartsias , Giorgos Papanastasiou , Chengjia Wang , Scott Semple , David E. Newby , Rohan Dharmakumar , Sotirios A. Tsaftaris

The Segment Anything Model (SAM) serves as a fundamental model for semantic segmentation and demonstrates remarkable generalization capabilities across a wide range of downstream scenarios. In this empirical study, we examine SAM's…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 An Wang , Mobarakol Islam , Mengya Xu , Yang Zhang , Hongliang Ren

The segmentation foundation model, e.g., Segment Anything Model (SAM), has attracted increasing interest in the medical image community. Early pioneering studies primarily concentrated on assessing and improving SAM's performance from the…

Image and Video Processing · Electrical Eng. & Systems 2024-06-19 Qin Li , Yizhe Zhang , Yan Li , Jun Lyu , Meng Liu , Longyu Sun , Mengting Sun , Qirong Li , Wenyue Mao , Xinran Wu , Yajing Zhang , Yinghua Chu , Shuo Wang , Chengyan Wang

Deep neural networks often suffer from poor generalization caused by complex and non-convex loss landscapes. One of the popular solutions is Sharpness-Aware Minimization (SAM), which smooths the loss landscape via minimizing the maximized…

Machine Learning · Computer Science 2022-10-25 Peng Mi , Li Shen , Tianhe Ren , Yiyi Zhou , Xiaoshuai Sun , Rongrong Ji , Dacheng Tao
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