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Artificial intelligence (AI)-based clinical decision support systems (CDSS) promise to enhance diagnostic accuracy and efficiency in computational pathology. However, human-AI collaboration might introduce automation bias, where users…

Human-Computer Interaction · Computer Science 2024-11-05 Emely Rosbach , Jonathan Ganz , Jonas Ammeling , Andreas Riener , Marc Aubreville

Passively collected behavioral health data from ubiquitous sensors holds significant promise to provide mental health professionals insights from patient's daily lives; however, developing analysis tools to use this data in clinical…

Major depressive disorder is a debilitating disease affecting 264 million people worldwide. While many antidepressant medications are available, few clinical guidelines support choosing among them. Decision support tools (DSTs) embodying…

Evaluating large language models (LLM) in clinical scenarios is crucial to assessing their potential clinical utility. Existing benchmarks rely heavily on static question-answering, which does not accurately depict the complex, sequential…

Human-Computer Interaction · Computer Science 2025-05-27 Samuel Schmidgall , Rojin Ziaei , Carl Harris , Eduardo Reis , Jeffrey Jopling , Michael Moor

While large language models (LLMs) have shown promise in diagnostic dialogue, their capabilities for effective management reasoning - including disease progression, therapeutic response, and safe medication prescription - remain…

Digital health tools have the potential to significantly improve the delivery of healthcare services. However, their adoption remains comparatively limited due, in part, to challenges surrounding usability and trust. Large Language Models…

Computation and Language · Computer Science 2024-03-01 Fergus Imrie , Paulius Rauba , Mihaela van der Schaar

How are AI assistants being used in the real world? While model providers in theory have a window into this impact via their users' data, both privacy concerns and practical challenges have made analyzing this data difficult. To address…

As Artificial Intelligence (AI) making advancements in medical decision-making, there is a growing need to ensure doctors develop appropriate reliance on AI to avoid adverse outcomes. However, existing methods in enabling appropriate AI…

Large language models (LLMs) show significant potential in healthcare, prompting numerous benchmarks to evaluate their capabilities. However, concerns persist regarding the reliability of these benchmarks, which often lack clinical…

Computation and Language · Computer Science 2026-04-30 Wenting Chen , Guo Yu , Yiu-Fai Cheung , Meidan Ding , Jie Liu , Zizhan Ma , Wenxuan Wang , Linlin Shen

Large Language Models (LLMs) are increasingly demonstrating the potential to reach human-level performance in generating clinical summaries from patient-clinician conversations. However, these summaries often focus on patients' biology…

Artificial intelligence (AI) systems increasingly match or surpass human experts in biomedical signal interpretation. However, their effective integration into clinical practice requires more than high predictive accuracy. Clinicians must…

Machine Learning · Computer Science 2025-10-27 Stefan Kraft , Andreas Theissler , Vera Wienhausen-Wilke , Gjergji Kasneci , Hendrik Lensch

Artificial intelligence (AI) is increasingly being considered to assist human decision-making in high-stake domains (e.g. health). However, researchers have discussed an issue that humans can over-rely on wrong suggestions of the AI model…

Human-Computer Interaction · Computer Science 2023-08-09 Min Hun Lee , Chong Jun Chew

Diabetic retinopathy (DR) is a leading cause of blindness worldwide, and AI systems can expand access to fundus photography screening. Current FDA-cleared systems primarily provide binary referral outputs, where this minimal output may…

Artificial Intelligence · Computer Science 2025-09-17 Nadim Barakat , William Lotter

Clinical trials are pivotal for developing new medical treatments but typically carry risks such as patient mortality and enrollment failure that waste immense efforts spanning over a decade. Applying artificial intelligence (AI) to predict…

Details of the designs and mechanisms in support of human-AI collaboration must be considered in the real-world fielding of AI technologies. A critical aspect of interaction design for AI-assisted human decision making are policies about…

Recent advances in large language models (LLMs) have shown promising results in medical diagnosis, with some studies indicating superior performance compared to human physicians in specific scenarios. However, the diagnostic capabilities of…

Artificial Intelligence · Computer Science 2025-03-24 Zhoujian Sun , Ziyi Liu , Cheng Luo , Jiebin Chu , Zhengxing Huang

Background: Large language models (LLMs) such as OpenAI's GPT-4 or Google's PaLM 2 are proposed as viable diagnostic support tools or even spoken of as replacements for "curbside consults". However, even LLMs specifically trained on medical…

Artificial Intelligence · Computer Science 2024-10-21 Gioele Barabucci , Victor Shia , Eugene Chu , Benjamin Harack , Nathan Fu

Primary care providers are vital for initial triage and referrals to specialty care. In glaucoma, asymptomatic and fast progression can lead to vision loss, necessitating timely referrals to specialists. However, primary eye care providers…

Human-Computer Interaction · Computer Science 2024-07-18 Catalina Gomez , Ruolin Wang , Katharina Breininger , Corinne Casey , Chris Bradley , Mitchell Pavlak , Alex Pham , Jithin Yohannan , Mathias Unberath

Large language models (LLMs) show promise for tailored healthcare communication but face challenges in interpretability and multi-task integration particularly for domain-specific needs like myopia, and their real-world effectiveness as…

Human-Computer Interaction · Computer Science 2025-07-29 Yue Wu , Xiaolan Chen , Weiyi Zhang , Shunming Liu , Wing Man Rita Sum , Xinyuan Wu , Xianwen Shang , Chea-su Kee , Mingguang He , Danli Shi

Artificial Intelligence (AI) has been advancing rapidly and with the advent of large language models (LLMs) in late 2022, numerous opportunities have emerged for adopting this technology across various domains, including medicine. These…

Computers and Society · Computer Science 2026-03-10 Amr Alshatnawi , Remi Sampaleanu , David Liebovitz