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Accurate representation of medical information is crucial for patient safety, yet artificial intelligence (AI) systems, such as Large Language Models (LLMs), encounter challenges in error-free clinical text interpretation. This paper…

Computation and Language · Computer Science 2024-04-30 Nadia Saeed

Peer review remains the central quality-control mechanism of science, yet its ability to fulfill this role is increasingly strained. Empirical studies document serious shortcomings: long publication delays, escalating reviewer burden…

The primary aim of this research was to address the limitations observed in the medical knowledge of prevalent large language models (LLMs) such as ChatGPT, by creating a specialized language model with enhanced accuracy in medical advice.…

Computation and Language · Computer Science 2023-06-27 Yunxiang Li , Zihan Li , Kai Zhang , Ruilong Dan , Steve Jiang , You Zhang

Clinician skepticism toward opaque AI hinders adoption in high-stakes healthcare. We present AICare, an interactive and interpretable AI copilot for collaborative clinical decision-making. By analyzing longitudinal electronic health…

Human-Computer Interaction · Computer Science 2026-02-03 Yinghao Zhu , Dehao Sui , Zixiang Wang , Xuning Hu , Lei Gu , Yifan Qi , Tianchen Wu , Ling Wang , Yuan Wei , Wen Tang , Zhihan Cui , Yasha Wang , Lequan Yu , Ewen M Harrison , Junyi Gao , Liantao Ma

AI-assisted decision making becomes increasingly prevalent, yet individuals often fail to utilize AI-based decision aids appropriately especially when the AI explanations are absent, potentially as they do not %understand reflect on AI's…

Human-Computer Interaction · Computer Science 2025-02-18 Zhuoyan Li , Hangxiao Zhu , Zhuoran Lu , Ziang Xiao , Ming Yin

Large language models (LLMs) often match or exceed clinician-level performance on medical benchmarks, yet very few are evaluated on real clinical data or examined beyond headline metrics. We present, to our knowledge, the first evaluation…

Large-scale language models (LLMs) often offer clinical judgments based on incomplete information, increasing the risk of misdiagnosis. Existing studies have primarily evaluated confidence in single-turn, static settings, overlooking the…

Computation and Language · Computer Science 2026-01-23 Zhiyao Ren , Yibing Zhan , Siyuan Liang , Guozheng Ma , Baosheng Yu , Dacheng Tao

Large language models (LLMs) have demonstrated notable potential in medical applications, yet they face substantial challenges in handling complex real-world clinical diagnoses using conventional prompting methods. Current prompt…

Artificial Intelligence · Computer Science 2026-03-02 Wenliang Li , Rui Yan , Xu Zhang , Li Chen , Hongji Zhu , Jing Zhao , Junjun Li , Mengru Li , Wei Cao , Zihang Jiang , Wei Wei , Kun Zhang , Shaohua Kevin Zhou

The integration of artificial intelligence [AI] into clinical trials has revolutionized the process of drug development and personalized medicine. Among these advancements, deep learning and predictive modelling have emerged as…

Machine Learning · Computer Science 2024-12-11 Sydney Anuyah , Mallika K Singh , Hope Nyavor

Advance Care Planning (ACP) allows individuals to specify their preferred end-of-life life-sustaining treatments before they become incapacitated by injury or terminal illness (e.g., coma, cancer, dementia). While online ACP offers high…

Medical education faces challenges in providing scalable, consistent clinical skills training. Simulation with standardized patients (SPs) develops communication and diagnostic skills but remains resource-intensive and variable in feedback…

Millions of users come to online peer counseling platforms to seek support. However, studies show that online peer support groups are not always as effective as expected, largely due to users' negative experiences with unhelpful counselors.…

Human-Computer Interaction · Computer Science 2025-03-14 Shang-Ling Hsu , Raj Sanjay Shah , Prathik Senthil , Zahra Ashktorab , Casey Dugan , Werner Geyer , Diyi Yang

Large language models (LLMs) have been increasingly adopted to support patients' healthcare-seeking in recent years. While prior patient-centered studies have examined the capabilities and experience of LLM-based tools in specific…

Human-Computer Interaction · Computer Science 2026-02-25 Yancheng Cao , Yishu Ji , Chris Yue Fu , Sahiti Dharmavaram , Meghan Turchioe , Natalie C Benda , Lena Mamykina , Yuling Sun , Xuhai "Orson" Xu

Large Language Models (LLMs) have emerged as powerful candidates to inform clinical decision-making processes. While these models play an increasingly prominent role in shaping the digital landscape, two growing concerns emerge in…

Computation and Language · Computer Science 2024-04-24 Raphael Poulain , Hamed Fayyaz , Rahmatollah Beheshti

Developing artificial intelligence (AI) for clinical research requires a comprehensive data foundation that supports model training and rigorous evaluation. Here, we introduce TrialPanorama, a large-scale structured resource that aggregates…

Artificial Intelligence · Computer Science 2025-12-17 Zifeng Wang , Jiacheng Lin , Qiao Jin , Junyi Gao , Jathurshan Pradeepkumar , Pengcheng Jiang , Zhiyong Lu , Jimeng Sun

The increasing complexity of clinical decision-making, alongside the rapid expansion of electronic health records (EHR), presents both opportunities and challenges for delivering data-informed care. This paper proposes a clinical decision…

Artificial Intelligence · Computer Science 2025-10-03 Leon Garza , Anantaa Kotal , Michael A. Grasso , Emre Umucu

The demand for psychological counselling has grown significantly in recent years, particularly with the global outbreak of COVID-19, which has heightened the need for timely and professional mental health support. Online psychological…

Computation and Language · Computer Science 2023-09-04 Tin Lai , Yukun Shi , Zicong Du , Jiajie Wu , Ken Fu , Yichao Dou , Ziqi Wang

Large language models (LLMs) are increasingly used for diagnostic tasks in medicine. In clinical practice, the correct diagnosis can rarely be immediately inferred from the initial patient presentation alone. Rather, reaching a diagnosis…

Artificial Intelligence · Computer Science 2026-02-20 Hui Min Wong , Philip Heesen , Pascal Janetzky , Martin Bendszus , Stefan Feuerriegel

Clinical decision-making is inherently complex, often influenced by cognitive biases, incomplete information, and case ambiguity. Large Language Models (LLMs) have shown promise as tools for supporting clinical decision-making, yet their…

Machine Learning · Computer Science 2025-07-10 Burcu Sayin , Ipek Baris Schlicht , Ngoc Vo Hong , Sara Allievi , Jacopo Staiano , Pasquale Minervini , Andrea Passerini

In this study, we investigate the feasibility of using a human-centered artificial intelligence (AI) chat platform where medical specialists collaboratively assess complex cases. As the target population for this platform, we focus on…

Human-Computer Interaction · Computer Science 2025-03-24 Shinnosuke Sawano , Satoshi Kodera
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