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The 5' UTR, a regulatory region at the beginning of an mRNA molecule, plays a crucial role in regulating the translation process and impacts the protein expression level. Language models have showcased their effectiveness in decoding the…

Machine Learning · Computer Science 2023-10-09 Yanyi Chu , Dan Yu , Yupeng Li , Kaixuan Huang , Yue Shen , Le Cong , Jason Zhang , Mengdi Wang

We present Token-UNet, adopting the TokenLearner and TokenFuser modules to encase Transformers into UNets. While Transformers have enabled global interactions among input elements in medical imaging, current computational challenges hinder…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Louis Fabrice Tshimanga , Andrea Zanola , Federico Del Pup , Manfredo Atzori

Transformers have revolutionized Computer Vision (CV) through self-attention mechanisms. However, their complexity makes latent token representations difficult to interpret. We introduce ULTra, a framework for interpreting Transformer…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Hesam Hosseini , Ghazal Hosseini Mighan , Amirabbas Afzali , Sajjad Amini , Amir Houmansadr

This work presents RNAdiffusion, a latent diffusion model for generating and optimizing discrete RNA sequences of variable lengths. RNA is a key intermediary between DNA and protein, exhibiting high sequence diversity and complex…

Machine Learning · Computer Science 2024-10-03 Kaixuan Huang , Yukang Yang , Kaidi Fu , Yanyi Chu , Le Cong , Mengdi Wang

Fully Convolutional Neural Networks (FCNNs) with contracting and expanding paths have shown prominence for the majority of medical image segmentation applications since the past decade. In FCNNs, the encoder plays an integral role by…

Image and Video Processing · Electrical Eng. & Systems 2021-10-12 Ali Hatamizadeh , Yucheng Tang , Vishwesh Nath , Dong Yang , Andriy Myronenko , Bennett Landman , Holger Roth , Daguang Xu

Messenger RNA (mRNA)-based vaccines are accelerating the discovery of new drugs and revolutionizing the pharmaceutical industry. However, selecting particular mRNA sequences for vaccines and therapeutics from extensive mRNA libraries is…

Quantitative Methods · Quantitative Biology 2024-12-23 Honggen Zhang , Xiangrui Gao , June Zhang , Lipeng Lai

Multivariate time series classification is of great importance in practical applications and is a challenging task. However, deep neural network models such as Transformers exhibit high accuracy in multivariate time series classification…

Machine Learning · Computer Science 2024-11-19 Mingsen Du , Yanxuan Wei , Yingxia Tang , Xiangwei Zheng , Shoushui Wei , Cun Ji

Accurate thyroid nodule segmentation in ultrasound images is critical for diagnosis and treatment planning. However, ambiguous boundaries between nodules and surrounding tissues, size variations, and the scarcity of annotated ultrasound…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Muhammad Umar Farooq , Abd Ur Rehman , Azka Rehman , Muhammad Usman , Dong-Kyu Chae , Junaid Qadir

Medical image segmentation is a difficult but important task for many clinical operations such as cardiac bi-ventricular volume estimation. More recently, there has been a shift to utilizing deep learning and fully convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2020-03-17 Jesse Sun , Fatemeh Darbehani , Mark Zaidi , Bo Wang

Recurrent neural networks (RNNs) sequentially process data by updating their state with each new data point, and have long been the de facto choice for sequence modeling tasks. However, their inherently sequential computation makes them…

Computation and Language · Computer Science 2019-03-06 Mostafa Dehghani , Stephan Gouws , Oriol Vinyals , Jakob Uszkoreit , Łukasz Kaiser

While previous CNN-based models have exhibited promising results for salient object detection (SOD), their ability to explore global long-range dependencies is restricted. Our previous work, the Visual Saliency Transformer (VST), addressed…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Nian Liu , Ziyang Luo , Ni Zhang , Junwei Han

The increasing number of protein sequences decoded from genomes is opening up new avenues of research on linking protein sequence to function with transformer neural networks. Recent research has shown that the number of known protein…

Machine Learning · Computer Science 2022-06-23 Anowarul Kabir , Amarda Shehu

Messenger RNA (mRNA) vaccines and therapeutics are emerging as powerful tools against a variety of diseases, including infectious diseases and cancer. The design of mRNA molecules, particularly the untranslated region (UTR) and coding…

Biomolecules · Quantitative Biology 2024-10-29 Yang Liu , Jie Gao , Xiaonan Zhang , Xiaomin Fang

In remote sensing, most segmentation networks adopt the UNet architecture, often incorporating modules such as Transformers or Mamba to enhance global-local feature interactions within decoder stages. However, these enhancements typically…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Chengqian Dai , Yonghong Guo , Hongzhao Xiang , Yigui Luo

Biomedical image segmentation is crucial for accurately diagnosing and analyzing various diseases. However, Convolutional Neural Networks (CNNs) and Transformers, the most commonly used architectures for this task, struggle to effectively…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Rong Zhou , Zhengqing Yuan , Zhiling Yan , Weixiang Sun , Kai Zhang , Yiwei Li , Yanfang Ye , Xiang Li , Lifang He , Lichao Sun

Transformer architecture has emerged to be successful in a number of natural language processing tasks. However, its applications to medical vision remain largely unexplored. In this study, we present UTNet, a simple yet powerful hybrid…

Computer Vision and Pattern Recognition · Computer Science 2021-09-29 Yunhe Gao , Mu Zhou , Dimitris Metaxas

Cross-modal transfer is helpful to enhance modality-specific discriminative power for scene recognition. To this end, this paper presents a unified framework to integrate the tasks of cross-modal translation and modality-specific…

Computer Vision and Pattern Recognition · Computer Science 2019-04-30 Dapeng Du , Limin Wang , Huiling Wang , Kai Zhao , Gangshan Wu

Inter reader variability and cross site domain shift challenge the automatic segmentation of prostate anatomy using T2 weighted MRI images. This study investigates whether transformer models can retain precision amid such heterogeneity. We…

Image and Video Processing · Electrical Eng. & Systems 2026-04-23 Shatha Abudalou , Jung Choi , Yasin Yilmaz , Yoganand Balagurunathan

This paper introduces a novel Token-and-Duration Transducer (TDT) architecture for sequence-to-sequence tasks. TDT extends conventional RNN-Transducer architectures by jointly predicting both a token and its duration, i.e. the number of…

Audio and Speech Processing · Electrical Eng. & Systems 2023-05-31 Hainan Xu , Fei Jia , Somshubra Majumdar , He Huang , Shinji Watanabe , Boris Ginsburg

Transformers have demonstrated strong potential in offline reinforcement learning (RL) by modeling trajectories as sequences of return-to-go, states, and actions. However, existing approaches such as the Decision Transformer(DT) and its…

Machine Learning · Computer Science 2025-10-27 Zhuojing Tian , Yushu Chen
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