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Affective computing - combining sensor technology, machine learning, and psychology - have been studied for over three decades and is employed in AI-powered technologies to enhance emotional awareness in AI systems, and detect symptoms of…

Audio and Speech Processing · Electrical Eng. & Systems 2026-04-21 Anders Rolighed Larsen , Sneha Das , Nicole Nadine Lønfeldt , Paula Petcu , Line Clemmensen

Predictive coding offers a potentially unifying account of cortical function -- postulating that the core function of the brain is to minimize prediction errors with respect to a generative model of the world. The theory is closely related…

Artificial Intelligence · Computer Science 2022-07-14 Beren Millidge , Anil Seth , Christopher L Buckley

Depression has affected millions of people worldwide and has become one of the most common mental disorders. Early mental disorder detection can reduce costs for public health agencies and prevent other major comorbidities. Additionally,…

Computation and Language · Computer Science 2024-04-09 Giuliano Lorenzoni , Cristina Tavares , Nathalia Nascimento , Paulo Alencar , Donald Cowan

The mechanisms of psychotic symptoms like hallucinations and delusions are often investigated in fully-formed illness, well after symptoms emerge. These investigations have yielded key insights, but are not well-positioned to reveal the…

Large-scale collaborative analysis of brain imaging data, in psychiatry and neu-rology, offers a new source of statistical power to discover features that boost ac-curacy in disease classification, differential diagnosis, and outcome…

Protein design has the potential to revolutionize biotechnology and medicine. While most efforts have focused on proteins with well-defined structures, increased recognition of the functional significance of intrinsically disordered…

Biomolecules · Quantitative Biology 2025-09-17 Giulio Tesei , Francesco Pesce , Kresten Lindorff-Larsen

Depression is a widespread mental health disorder, yet its automatic detection remains challenging. Prior work has explored unimodal and multimodal approaches, with multimodal systems showing promise by leveraging complementary signals.…

Artificial Intelligence · Computer Science 2026-03-24 Annisaa Fitri Nurfidausi , Eleonora Mancini , Paolo Torroni

Mental disorders like major depressive disorder can be seen as complex dynamical systems. In this study we investigate the dynamic behaviour of individuals to see whether or not we can expect a transition to another mood state. We introduce…

Physics and Society · Physics 2019-03-27 Jolanda J Kossakowski , Marijke C M Gordijn , Harriette Riese , Lourens J Waldorp

In this paper, we aimed at reviewing several different approaches present today in the search for more accurate diagnostic and treatment management in mental healthcare. Our focus is on mood disorders, and in particular on the major…

Neurons and Cognition · Quantitative Biology 2019-03-28 Milena Cukic Radenkovic

The theoretical basis of neuronal coding, associated with short term degradation in synaptic transmission, is a matter of debate in the literature. In fact, electrophysiological signals are commonly characterized as inversely proportional…

Neurons and Cognition · Quantitative Biology 2017-11-21 A. J. da Silva , S. Floquet , D. O. C. Santos

Background: Reliable prediction of clinical progression over time can improve the outcomes of depression. Little work has been done integrating various risk factors for depression, to determine the combinations of factors with the greatest…

Machine Learning · Statistics 2023-07-06 Runa Bhaumik , Jonathan Stange

In recent years, research unveiled more and more evidence for the so-called Bayesian Brain Paradigm, i.e. the human brain is interpreted as a probabilistic inference machine and Bayesian modelling approaches are hence used successfully. One…

Neural and Evolutionary Computing · Computer Science 2019-04-30 Kevin Jasberg , Sergej Sizov

Social media has recently emerged as a premier method to disseminate information online. Through these online networks, tens of millions of individuals communicate their thoughts, personal experiences, and social ideals. We therefore…

Social and Information Networks · Computer Science 2016-07-26 Moin Nadeem

Social media channels, such as Facebook, Twitter, and Instagram, have altered our world forever. People are now increasingly connected than ever and reveal a sort of digital persona. Although social media certainly has several remarkable…

Social and Information Networks · Computer Science 2020-08-26 Hatoon S. AlSagri , Mourad Ykhlef

Structured internal representations (cognitive maps) shape cognition, from imagining the future and counterfactual past, to transferring knowledge to new settings. Our understanding of how such representations are formed and maintained in…

Neurons and Cognition · Quantitative Biology 2024-10-07 Matthew M Nour , Yunzhe Liu , Mohamady El-Gaby , Robert A McCutcheon , Raymond J Dolan

In today's interconnected society, social media platforms have become an important part of our lives, where individuals virtually express their thoughts, emotions, and moods. These expressions offer valuable insights into their mental…

Machine Learning · Computer Science 2025-01-28 Yusif Ibrahimov , Tarique Anwar , Tommy Yuan

Self-disclosed mental health diagnoses, which serve as ground truth annotations of mental health status in the absence of clinical measures, underpin the conclusions behind most computational studies of mental health language from the last…

Machine Learning · Computer Science 2022-06-23 Keith Harrigian , Mark Dredze

The fundamental, powerful process of computation in the brain has been widely misunderstood. The paper [1] associates the general failure to build intelligent thinking machines with current reductionist principles of temporal coding and…

Neural and Evolutionary Computing · Computer Science 2012-10-09 Dorian Aur

Mental disorders such as depression and anxiety have been increasing at alarming rates in the worldwide population. Notably, the major depressive disorder has become a common problem among higher education students, aggravated, and maybe…

Computation and Language · Computer Science 2020-03-31 Paulo Mann , Aline Paes , Elton H. Matsushima

Major depressive disorder (MDD) is a complex psychiatric disorder that affects the lives of hundreds of millions of individuals around the globe. Even today, researchers debate if morphological alterations in the brain are linked to MDD,…

Quantitative Methods · Quantitative Biology 2025-01-27 Roberto Goya-Maldonado , Tracy Erwin-Grabner , Ling-Li Zeng , Christopher R. K. Ching , Andre Aleman , Alyssa R. Amod , Zeynep Basgoze , Francesco Benedetti , Bianca Besteher , Katharina Brosch , Robin Bülow , Romain Colle , Colm G. Connolly , Emmanuelle Corruble , Baptiste Couvy-Duchesne , Kathryn Cullen , Udo Dannlowski , Christopher G. Davey , Annemiek Dols , Jan Ernsting , Jennifer W. Evans , Lukas Fisch , Paola Fuentes-Claramonte , Ali Saffet Gonul , Ian H. Gotlib , Hans J. Grabe , Nynke A. Groenewold , Dominik Grotegerd , Tim Hahn , J. Paul Hamilton , Laura K. M. Han , Ben J. Harrison , Tiffany C. Ho , Neda Jahanshad , Alec J. Jamieson , Andriana Karuk , Tilo Kircher , Bonnie Klimes-Dougan , Sheri-Michelle Koopowitz , Thomas Lancaster , Ramona Leenings , Meng Li , David E. J. Linden , Frank P. MacMaster , David M. A. Mehler , Susanne Meinert , Elisa Melloni , Bryon A. Mueller , Benson Mwangi , Igor Nenadić , Amar Ojha , Yasumasa Okamoto , Mardien L. Oudega , Brenda W. J. H. Penninx , Sara Poletti , Edith Pomarol-Clotet , Maria J. Portella , Elena Pozzi , Joaquim Radua , Elena Rodríguez-Cano , Matthew D. Sacchet , Raymond Salvador , Anouk Schrantee , Kang Sim , Jair C. Soares , Aleix Solanes , Dan J. Stein , Frederike Stein , Aleks Stolicyn , Sophia I. Thomopoulos , Yara J. Toenders , Aslihan Uyar-Demir , Eduard Vieta , Yolanda Vives-Gilabert , Henry Völzke , Martin Walter , Heather C. Whalley , Sarah Whittle , Nils Winter , Katharina Wittfeld , Margaret J. Wright , Mon-Ju Wu , Tony T. Yang , Carlos Zarate , Dick J. Veltman , Lianne Schmaal , Paul M. Thompson
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