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Related papers: Depression as a disorder of distributional coding

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With ubiquity of social media platforms, millions of people are sharing their online persona by expressing their thoughts, moods, emotions, feelings, and even their daily struggles with mental health issues voluntarily and publicly on…

Major Depressive Disorder (MDD) is a clinically heterogeneous syndrome with diverse etiological pathways. Traditional Epigenome-Wide Association Studies (EWAS) have successfully identified risk loci based on differential methylation…

Computational Engineering, Finance, and Science · Computer Science 2026-01-27 Mingyan Liu , Min Huang

Both neurobiological and environmental factors are known to play a role in the origin of schizophrenia, but no model has been proposed that accounts for both. This work presents a functional model of schizophrenia that merges psychodynamic…

Neurons and Cognition · Quantitative Biology 2017-03-10 Alessandro Fontana

We currently observe a disconcerting phenomenon in machine learning studies in psychiatry: While we would expect larger samples to yield better results due to the availability of more data, larger machine learning studies consistently show…

Brain decoding involves the determination of a subject's cognitive state or an associated stimulus from functional neuroimaging data measuring brain activity. In this setting the cognitive state is typically characterized by an element of a…

Machine Learning · Statistics 2015-04-14 Nicole Croteau , Farouk S. Nathoo , Jiguo Cao , Ryan Budney

Mental distress like depression and anxiety contribute to the largest proportion of the global burden of diseases. Automated diagnosis systems of such disorders, empowered by recent innovations in Artificial Intelligence, can pave the way…

Audio and Speech Processing · Electrical Eng. & Systems 2023-06-23 Mashrura Tasnim , Malikeh Ehghaghi , Brian Diep , Jekaterina Novikova

Mental-illness stigma is a persistent social problem, hampering both treatment-seeking and recovery. Accordingly, there is a pressing need to understand it more clearly, but analyzing the relevant data is highly labor-intensive. Therefore,…

Human-Computer Interaction · Computer Science 2025-02-11 Han Meng , Renwen Zhang , Ganyi Wang , Yitian Yang , Peinuan Qin , Jungup Lee , Yi-Chieh Lee

Depression is a common disease worldwide. It is difficult to diagnose and continues to be underdiagnosed. Because depressed patients constantly share their symptoms, major life events, and treatments on social media, researchers are turning…

Computation and Language · Computer Science 2025-10-27 Wenli Zhang , Jiaheng Xie , Zhu Zhang , Xiang Liu

With more than 300 million people depressed worldwide, depression is a global problem. Due to access barriers such as social stigma, cost, and treatment availability, 60% of mentally-ill adults do not receive any mental health services.…

Computer Vision and Pattern Recognition · Computer Science 2018-11-28 Albert Haque , Michelle Guo , Adam S Miner , Li Fei-Fei

Automatic depression detection on Twitter can help individuals privately and conveniently understand their mental health status in the early stages before seeing mental health professionals. Most existing black-box-like deep learning…

Computation and Language · Computer Science 2022-09-16 Sooji Han , Rui Mao , Erik Cambria

The high prevalence of depression in society has given rise to the need for new digital tools to assist in its early detection. To this end, existing research has mainly focused on detecting depression in the domain of social media, where…

Computation and Language · Computer Science 2022-04-25 Petr Lorenc , Ana-Sabina Uban , Paolo Rosso , Jan Šedivý

Depression is one of the leading causes of disability worldwide, posing a severe burden on individuals, healthcare systems, and society at large. Recent advancements in Large Language Models (LLMs) have shown promise in addressing mental…

Computation and Language · Computer Science 2025-02-11 Shiyu Teng , Jiaqing Liu , Rahul Kumar Jain , Shurong Chai , Ruibo Hou , Tomoko Tateyama , Lanfen Lin , Yen-wei Chen

INTRODUCTION: The pharmacological treatment of Major Depressive Disorder (MDD) relies on a trial-and-error approach. We introduce an artificial intelligence (AI) model aiming to personalize treatment and improve outcomes, which was deployed…

Due to the complexity of the human body, most diseases present a high inter-personal variability in the way they manifest, i.e. in their phenotype, which has important clinical repercussions - as for instance the difficulty in defining…

Physics and Society · Physics 2018-06-06 Massimiliano Zanin , Juan Manuel Tuñas , Ernestina Menasalvas

Depression is a common mental illness that has to be detected and treated at an early stage to avoid serious consequences. There are many methods and modalities for detecting depression that involves physical examination of the individual.…

Artificial Intelligence · Computer Science 2022-02-08 Kayalvizhi S , Thenmozhi D

In this work we propose a machine learning model for depression detection from transcribed clinical interviews. Depression is a mental disorder that impacts not only the subject's mood but also the use of language. To this end we use a…

Computation and Language · Computer Science 2020-06-16 D. Xezonaki , G. Paraskevopoulos , A. Potamianos , S. Narayanan

While depression has been studied via multimodal non-verbal behavioural cues, head motion behaviour has not received much attention as a biomarker. This study demonstrates the utility of fundamental head-motion units, termed \emph{kinemes},…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Monika Gahalawat , Raul Fernandez Rojas , Tanaya Guha , Ramanathan Subramanian , Roland Goecke

The differential diagnosis of neurodegenerative diseases, characterized by overlapping symptoms, may be challenging. Brain imaging coupled with artificial intelligence has been previously proposed for diagnostic support, but most of these…

Image and Video Processing · Electrical Eng. & Systems 2025-02-21 Pierrick Coupé , Boris Mansencal , José V. Manjón , Patrice Péran , Wassilios G. Meissner , Thomas Tourdias , Vincent Planche

This work presents a comprehensive theory of consciousness grounded in mathematical formalism and supported by clinical data analysis. The framework developed herein demonstrates that consciousness exists as a continuous, non-monotonic…

Neurons and Cognition · Quantitative Biology 2025-07-04 Diogo Sousa

Depression disorder is a serious health condition that has affected the lives of millions of people around the world. Diagnosis of depression is a challenging practice that relies heavily on subjective studies and, in most cases, suffers…

Signal Processing · Electrical Eng. & Systems 2025-03-26 Amir Nassibi , Christos Papavassiliou , Ildar Rakhmatulin , Danilo Mandic , S. Farokh Atashzar